Search Results - "FLEMMING, P"

A liver secretome gene signature-based approach for determining circulating biomarkers of NAFLD severity by Hagemann, Christoffer A, Legart, Christian, Møllerhøj, Mathias B, Madsen, Martin R, Hansen, Henrik H, Kønig, Merete J, Helgstrand, Frederik, Hjørne, Flemming P, Toxværd, Anders, Langhoff, Jill L, Kielgast, Urd L, Gluud, Lise L, Ægidius, Helene, Rigbolt, Kristoffer T. G, Vilsbøll, Tina, Jelsing, Jacob, Knop, Filip K

“…Non-invasive biomarkers of non-alcoholic fatty liver disease (NAFLD) supporting diagnosis and monitoring disease progression are urgently needed. The present…”
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Roentgen Examination of Ileocaecal Tuberculosis with Special Reference to the so-called Stierlin-Sign by Møller, P Flemming

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Multi-Center Follow-up Study to Develop a Classification System Which Differentiates Mucinous Cystic Neoplasm of the Liver and Benign Hepatic Cyst Using Machine Learning by Hardie, Andrew D, Chamberlin, Jordan H, Boyum, James H, Sharbidre, Kedar G, Petrocelli, Robert, Flemming, Brian P, Zahid, Mohd, Venkatesh, Sudhakar K, Mruthyunjayappa, Smitha, Hajdu, Cristina H, Kovacs, Mark D

“…RATIONALE AND OBJECTIVESTo date, no clinically useful classification system has been developed for reliably differentiating mucinous cystic neoplasm (MCN) from…”
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A liver secretome gene signature-based approach for determining circulating biomarkers of NAFLD severity by Christoffer A. Hagemann, Christian Legart, Mathias B. Møllerhøj, Martin R. Madsen, Henrik H. Hansen, Merete J. Kønig, Frederik Helgstrand, Flemming P. Hjørne, Anders Toxværd, Jill L. Langhoff, Urd L. Kielgast, Lise L. Gluud, Helene Ægidius, Kristoffer T. G. Rigbolt, Tina Vilsbøll, Jacob Jelsing, Filip K. Knop

“…Non-invasive biomarkers of non-alcoholic fatty liver disease (NAFLD) supporting diagnosis and monitoring disease progression are urgently needed. The present…”
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IL‐8 correlates with nonresponse to neoadjuvant nivolumab in HPV positive HNSCC via a potential extracellular vesicle miR‐146a mediated mechanism by Hill, Brianna L., Calder, Alyssa N., Flemming, Joseph P., Guo, Yiyang, Gilmore, Sydney L., Trofa, Melissa A., Daniels, Sean K., Nielsen, Torbjoern N., Gleason, Laura K., Antysheva, Zoya, Demina, Ksenia, Kotlov, Nikita, Davitt, Christopher J. H., Cognetti, David M., Prendergast, George C., Snook, Adam E., Johnson, Jennifer M., Kumar, Gaurav, Linnenbach, Alban J., Martinez‐Outschoorn, Ubaldo, South, Andrew P., Curry, Joseph M., Harshyne, Larry A., Luginbuhl, Adam J., Mahoney, Mỹ G.

“…Therapy using anti‐PD‐1 immune checkpoint inhibitors (ICI) has revolutionized the treatment of many cancers including head and neck squamous cell carcinomas…”
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miRNA- and cytokine-associated extracellular vesicles mediate squamous cell carcinomas by Flemming, Joseph P., Hill, Brianna L., Haque, Mohammed W., Raad, Jessica, Bonder, Claudine S., Harshyne, Larry A., Rodeck, Ulrich, Luginbuhl, Adam, Wahl, James K., Tsai, Kenneth Y., Wermuth, Peter J., Overmiller, Andrew M., Mahoney, Mỹ G.

“…Exosomes, or small extracellular vesicles (sEVs), serve as intercellular messengers with key roles in normal and pathological processes. Our previous work had…”
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The Accuracy of Single Photon Emission Computed Tomography/Computed Tomography Arthrography in Evaluating Aseptic Loosening of Hip and Knee Prostheses by Abele, Jonathan T., MD, Swami, Vimarsha G, Russell, Gordon, MD, Masson, Edward C.O., MD, Flemming, Jeffrey P., MD

“…Abstract Aseptic loosening represents the most common complication associated with hip and knee arthroplasty and is a common indication for surgical revision…”
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Cytokine Profiling in Low- and High-Density Small Extracellular Vesicles from Epidermoid Carcinoma Cells by Flemming, Joseph P., Hill, Brianna L., Anderson-Pullinger, Lauren, Harshyne, Larry A., Mahoney, Mỹ G.

“…Exosomes or small extracellular vesicles (sEVs) are membrane-bound nanoparticles that carry various macromolecules and act as autocrine and paracrine signaling…”
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Multiple functional polymorphisms in the G6PC2 gene contribute to the association with higher fasting plasma glucose levels by Baerenwald, D. A., Bonnefond, A., Bouatia-Naji, N., Flemming, B. P., Umunakwe, O. C., Oeser, J. K., Pound, L. D., Conley, N. L., Cauchi, S., Lobbens, S., Eury, E., Balkau, B., Lantieri, O., Dadi, P. K., Jacobson, D. A., Froguel, P., O’Brien, R. M.

“…Aims/hypothesis We previously identified the G6PC2 locus as a strong determinant of fasting plasma glucose (FPG) and showed that a common G6PC2 intronic single…”
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Sequential ortho-lithiations; the sulfoxide group as a relay to enable meta-substitution by Flemming, Jonathan P, Berry, Malcolm B, Brown, John M

“…Sulfoxides are known to be powerful directing groups for ortho-lithiation, even in competition with other directors. This has been utilised to introduce…”
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Retrospective analysis of prognostic factors after liver resection and transplantation for cholangiocellular carcinoma by Weimann, A., Varnholt, H., Schlitt, H. J., Lang, H., Flemming, P., Hustedt, C., Tusch, G., Raab, R.

“…Background Cholangiocellular carcinoma is an uncommon primary liver cancer, which may be mixed with hepatocellular carcinoma. A retrospective analysis was…”
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Extracellular Vesicles in the Skin Microenvironment: Emerging Roles as Biomarkers and Therapeutic Tools in Dermatologic Health and Disease by Flemming, Joseph P, Wermuth, Peter J, Mahoney, Mỹ G

“…The recent discovery of extracellular vesicles (EVs) carrying cargo consisting of various bioactive macromolecules that can modulate the phenotype of recipient…”
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Presumed cryptogenic liver disease in Germany: High prevalence of autoantibody-negative autoimmune hepatitis, low prevalence of NASH, no evidence for occult viral etiology by Heringlake, S, Schütte, A, Flemming, P, Schmiegel, W, Manns, M P, Tillmann, H L

“…Aim was to investigate possible underlying causes of presumed cryptogenic liver disease. A cohort of 126 consecutive patients with presumed cryptogenic…”
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Generation and analysis of genetically defined liver carcinomas derived from bipotential liver progenitors by Zender, L, Xue, W, Cordón-Cardo, C, Hannon, G J, Lucito, R, Powers, S, Flemming, P, Spector, M S, Lowe, S W

“…Hepatocellular carcinoma is a chemoresistant cancer and a leading cause of cancer mortality; however, the molecular mechanisms responsible for the aggressive…”
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Long-Range Enhancers Are Required to Maintain Expression of the Autoantigen Islet-Specific Glucose-6-Phosphatase Catalytic Subunit–Related Protein in Adult Mouse Islets In Vivo by Wang, Yingda, Flemming, Brian P, Martin, Cyrus C, Allen, Shelley R, Walters, Jay, Oeser, James K, Hutton, John C, O'Brien, Richard M

“…Long-Range Enhancers Are Required to Maintain Expression of the Autoantigen Islet-Specific Glucose-6-Phosphatase Catalytic Subunit–Related Protein in Adult…”
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Primary Penile Squamous Cell Carcinoma in a Patient with Metastatic Adenocarcinoma of Colon to Liver: A Case Report by Dalton, Raeann M., Son, Young, Flemming, Joseph P, Junayed, Abdullah, Thomas, Brian M, Fink, Benjamin A, Klimowich, Katelyn M, Mueller, Thomas, Dorsey, Philip

“…Penile squamous cell carcinoma (SCC) is a rare malignancy associated with human papillomavirus and immunosuppression. If not detected early in its course,…”
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Telomere shortening of epithelial cells characterises the adenoma-carcinoma transition of human colorectal cancer by Plentz, R R, Wiemann, S U, Flemming, P, Meier, P N, Kubicka, S, Kreipe, H, Manns, M P, Rudolph, K L

“…Background and aims: Chromosomal instability is one of the most consistent markers of sporadic colorectal cancer in humans. There is growing evidence that…”
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Foxa2 and MafA regulate islet-specific glucose-6-phosphatase catalytic subunit-related protein gene expression by Martin, Cyrus C, Flemming, Brian P, Wang, Yingda, Oeser, James K, O'Brien, Richard M

“…Islet-specific glucose-6-phosphatase catalytic subunit-related protein (IGRP/G6PC2) is a major autoantigen in both mouse and human type 1 diabetes. IGRP is…”
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The role of nemolizumab in the treatment of atopic dermatitis for the adult population by Prajapati, Stuti, Flemming, Joseph P, Khan, Danyaal, Han, Haowei, How, Brian, Rozenberg, Suzanne Sirota, Feldman, Steven R

“…Atopic dermatitis (AD) often requires long-term treatment that may be associated with adverse effects. This review aims to characterize nemolizumab as a…”
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Sequence variation between the mouse and human glucose-6-phosphatase catalytic subunit gene promoters results in differential activation by peroxisome proliferator activated receptor gamma coactivator-1α by Schilling, M. M, Oeser, J. K, Chandy, J. K, Flemming, B. P, Allen, S. R, O'Brien, R. M

“…Aims/hypothesis The glucose-6-phosphatase catalytic subunit (G6PC) plays a key role in hepatic glucose production by catalysing the final step in…”
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