Search Results - "FLAVIN, Richard J"

MYC Regulation of a "Poor-Prognosis" Metastatic Cancer Cell State by Wolfer, Anita, Wittner, Ben S., Irimia, Daniel, Flavin, Richard J., Lupien, Mathieu, Gunawardane, Ruwanthi N., Meyer, Clifford A., Lightcap, Eric S., Tamayo, Pablo, Mesirov, Jill P., Liu, X. Shirley, Shioda, Toshi, Toner, Mehmet, Loda, Massimo, Brown, Myles, Brugge, Joan S., Ramaswamy, Sridhar

“…Gene expression signatures are used in the clinic as prognostic tools to determine the risk of individual patients with localized breast tumors developing…”
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Analysis of the 10q11 cancer risk locus implicates MSMB and NCOA4 in human prostate tumorigenesis by Pomerantz, Mark M, Shrestha, Yashaswi, Flavin, Richard J, Regan, Meredith M, Penney, Kathryn L, Mucci, Lorelei A, Stampfer, Meir J, Hunter, David J, Chanock, Stephen J, Schafer, Eric J, Chan, Jennifer A, Tabernero, Josep, Baselga, José, Richardson, Andrea L, Loda, Massimo, Oh, William K, Kantoff, Philip W, Hahn, William C, Freedman, Matthew L

“…Genome-wide association studies (GWAS) have established a variant, rs10993994, on chromosome 10q11 as being associated with prostate cancer risk. Since the…”
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Potentially important microRNA cluster on chromosome 17p13.1 in primary peritoneal carcinoma by Flavin, Richard J, Smyth, Paul C, Laios, Alexandros, O'Toole, Sharon A, Barrett, Ciara, Finn, Stephen P, Russell, Susan, Ring, Martina, Denning, Karen M, Li, Jinghuan, Aherne, Sinead T, Sammarae, Dania A, Aziz, Natasha A, Alhadi, Araibi, Sheppard, Brian L, Lao, Kai, Sheils, Orla M, O'Leary, John J

“…MicroRNAs are a group of small non-coding RNAs approximately 22 nucleotides in length. Recent work has shown differential expression of mature microRNAs in…”
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Geographical mapping of a multifocal thyroid tumour using genetic alteration analysis & miRNA profiling by Aherne, Sinéad T, Smyth, Paul C, Flavin, Richard J, Russell, Susan M, Denning, Karen M, Li, Jing Huan, Guenther, Simone M, O'Leary, John J, Sheils, Orla M

“…Papillary thyroid carcinoma (PTC) frequently presents as multiple tumour-foci within a single thyroid gland or pluriform, with synchronous tumours comprising…”
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Cetuximab Response of Lung Cancer―Derived EGF Receptor Mutants Is Associated with Asymmetric Dimerization by JEONGHEE CHO, LIANG CHEN, GREULICH, Heidi, JOHNSON, Bruce E, ECK, Michael J, JÄNNE, Pasi A, WONG, Kwok-Kin, MEYERSON, Matthew, SANGJI, Naveen, OKABE, Takafumi, YONESAKA, Kimio, FRANCIS, Joshua M, FLAVIN, Richard J, JOHNSON, William, JIHYUN KWON, SOYOUNG YU

“…Kinase domain mutations of the EGF receptor (EGFR) are common oncogenic events in lung adenocarcinoma. Here, we explore the dependency upon asymmetric…”
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Regulation of microRNA biosynthesis and expression in 2102Ep embryonal carcinoma stem cells is mirrored in ovarian serous adenocarcinoma patients by Gallagher, Michael F, Flavin, Richard J, Elbaruni, Salah A, McInerney, Jamie K, Smyth, Paul C, Salley, Yvonne M, Vencken, Sebastian F, O'Toole, Sharon A, Laios, Alexandros, Lee, Mathia Yc, Denning, Karen, Li, Jinghuan, Aherne, Sinead T, Lao, Kai Q, Martin, Cara M, Sheils, Orla M, O'Leary, John J

“…Tumours with high proportions of differentiated cells are considered to be of a lower grade to those containing high proportions of undifferentiated cells…”
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Suppression of cancer stemness p21-regulating mRNA and microRNA signatures in recurrent ovarian cancer patient samples by Gallagher, Michael F, Heffron, Cynthia Cbb, Laios, Alexandros, O'Toole, Sharon A, Ffrench, Brendan, Smyth, Paul C, Flavin, Richard J, Elbaruni, Salah A, Spillane, Cathy D, Martin, Cara M, Sheils, Orla M, O'Leary, John J

“…Malignant ovarian disease is characterised by high rates of mortality due to high rates of recurrent chemoresistant disease. Anecdotal evidence indicates this…”
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β-Catenin Is a Useful Adjunct Immunohistochemical Marker for the Diagnosis of Pulmonary Lymphangioleiomyomatosis by FLAVIN, Richard J, COOK, Jennifer, FIORENTINO, Michelangelo, BAILEY, Dyane, BROWN, Myles, LODA, Massimo F

“…Lymphangioleiomyomatosis (LAM) is a rare multisystem disease leading to cystic destruction of the lung parenchyma and is associated with abnormal smooth muscle…”
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Altered eIF6 and Dicer expression is associated with clinicopathological features in ovarian serous carcinoma patients by Flavin, Richard J, Smyth, Paul C, Finn, Stephen P, Laios, Alexandros, O'Toole, Sharon A, Barrett, Ciara, Ring, Martina, Denning, Karen M, Li, Jinghuan, Aherne, Sinead T, Aziz, Natasha A, Alhadi, Araibi, Sheppard, Brian L, Loda, Massimo, Martin, Cara, Sheils, Orla M, O'Leary, John J

“…MicroRNAs are a group of small non-coding RNAs approximately 22 nucleotides in length. Recent work has shown differential expression of mature microRNAs in…”
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Genetic variation in RNASEL associated with prostate cancer risk and progression by Meyer, Mara S., Penney, Kathryn L., Stark, Jennifer R., Schumacher, Fredrick R., Sesso, Howard D., Loda, Massimo, Fiorentino, Michelangelo, Finn, Stephen, Flavin, Richard J., Kurth, Tobias, Price, Alkes L., Giovannucci, Edward L., Fall, Katja, Stampfer, Meir J., Ma, Jing, Mucci, Lorelei A.

“…Variation in genes contributing to the host immune response may mediate the relationship between inflammation and prostate carcinogenesis. RNASEL at chromosome…”
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A molecular expression signature distinguishing follicular lesions in thyroid carcinoma using preamplification RT-PCR in archival samples by Denning, Karen M, Smyth, Paul C, Cahill, Susanne F, Finn, Stephen P, Conlon, Eilish, Li, JingHuan, Flavin, Richard J, Aherne, Sinead T, Guenther, Simone M, Ferlinz, Astrid, O'Leary, John J, Sheils, Orla M

“…Follicular variant of papillary thyroid carcinoma is a lesion that frequently causes difficulties from a diagnostic perspective in the laboratory. The purpose…”
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FOXO3a loss is a frequent early event in high-grade pelvic serous carcinogenesis by Levanon, K, Sapoznik, S, Bahar-Shany, K, Brand, H, Shapira-Frommer, R, Korach, J, Hirsch, M S, Roh, M H, Miron, A, Liu, J F, Vena, N, Ligon, A H, Fotheringham, S, Bailey, D, Flavin, R J, Birrer, M J, Drapkin, R I

“…Serous ovarian carcinoma is the most lethal gynecological malignancy in Western countries. The molecular events that underlie the development of the disease…”
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[Beta]-Catenin Is a Useful Adjunct Immunohistochemical Marker for the Diagnosis of Pulmonary Lymphangioleiomyomatosis by Flavin, Richard J, Cook, Jennifer, Fiorentino, Michelangelo, Bailey, Dyane, Brown, Myles, Loda, Massimo F

“…Lymphangioleiomyomatosis (LAM) is a rare multisystem disease leading to cystic destruction of the lung parenchyma and is associated with abnormal smooth muscle…”
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Analysis of the 10q11 Cancer Risk Locus Implicates MSMB and NCOA4 in Human Prostate Tumorigenesis: e1001204 by Pomerantz, Mark M, Shrestha, Yashaswi, Flavin, Richard J, Regan, Meredith M, Penney, Kathryn L, Mucci, Lorelei A, Stampfer, Meir J, Hunter, David J, Chanock, Stephen J, Schafer, Eric J, Chan, Jennifer A, Tabernero, Josep, Baselga, José, Richardson, Andrea L, Loda, Massimo, Oh, William K, Kantoff, Philip W, Hahn, William C, Freedman, Matthew L

“…Genome-wide association studies (GWAS) have established a variant, rs10993994, on chromosome 10q11 as being associated with prostate cancer risk. Since the…”
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Abstract A177: Cetuximab resistance associated with dimerization-independence of oncogenic EGFR mutants by Cho, Jeonghee, Chen, Liang, Sangji, Naveen, Du, Jinyan, Okabe, Takafumi, Yonesaka, Kimio, Francis, Joshua M., Flavin, Richard J., Yu, Soyoung, Greulich, Heidi E., Johnson, Bruce E., Eck, Michael J., Jänne, Pasi A., Wong, Kwok-Kin, Meyerson, Matthew

“…Abstract Asymmetric dimerization of the kinase domain is a key mechanism for activation of the epidermal growth factor receptor (EGFR). Here, we show that…”
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Abstract 3300: MYC regulation of a “poor prognosis” metastatic cancer cell state by Wolfer, Anita, Wittner, Ben S., Irimia, Daniel, Flavin, Richard J., Lupien, Mathieu, Gunawardane, Ruwanthi N., Meyer, Clifford A., Lightcap, Eric S., Tamayo, Pablo, Mesirov, Jill P., Liu, Xiaole S., Shioda, Toshihiro, Toner, Mehmet, Loda, Massimo, Brown, Myles, Brugge, Joan S., Ramaswamy, Sridhar

“…Abstract Gene expression signatures are used clinically as prognostic tools to determine the risk of individual patients with localized breast tumors…”
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Abstract B106: Alcohol consumption and TMPRSS2:ERG gene fusion in prostate cancer by Lin, Shih-Wen, Stark, Jennifer R., Meyer, Mara, Penney, Kathryn L., Hendrickson, Whitney, Kasperzyk, Julie L., Ma, Jing, Sesso, Howard D., Flavin, Richard J., Giovannucci, Edward, Stampfer, Meir, Loda, Massimo, Mucci, Lorelei A.

“…Abstract Objectives: The novel TMPRSS2:ERG gene fusion is a common somatic event in prostate cancer that in some studies is linked with a more aggressive…”
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