Search Results - "FITZSIMMONS, W. E"

Phase III study comparing methotrexate and tacrolimus (Prograf, FK506) with methotrexate and cyclosporine for graft-versus-host disease prophylaxis after HLA-identical sibling bone marrow transplantation by RATANATHARATHORN, V, NASH, R. A, VAN DER JAGT, R, HERZIG, R. H, LITZOW, M. R, WOLFF, S. N, LONGO, W. L, PETERSEN, F. B, KARANES, C, AVALOS, B, STORB, R, BUELL, D. N, PRZEPIORKA, D, MAHER, R. M, FITZSIMMONS, W. E, WINGARD, J. R, DEVINE, S. M, KLEIN, J. L, WEISDORF, D, FAY, J. W, NADEMANEE, A, ANTIN, J. H, CHRISTIANSEN, N. P

“…We report the results of a phase III open-label, randomized, multicenter trial comparing tacrolimus/methotrexate to cyclosporine/methotrexate for…”
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Relationship of FK506 whole blood concentrations and efficacy and toxicity after liver and kidney transplantation by KERSHNER, R. P, FITZSIMMONS, W. E

“…FK506 (tacrolimus) is a safe and effective immunosuppressant for the prevention of organ rejection after organ transplantation. FK506 has a relatively narrow…”
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Association of Discharge Immunosuppression Regimen and Post-Transplant Outcomes in Lung Transplantation: An Analysis of OPTN Data by Cherikh, W.S., Plucinski, B.J., Palmer, S., Fitzsimmons, W.E.

“…The optimal immunosuppressive (IS) regimen after lung (LU) transplant is unknown, therefore we sought to examine OPTN data to compare the impact of 4 different…”
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Clinical Utility of Monitoring Tacrolimus Blood Concentrations in Liver Transplant Patients by Venkataramanan, Raman, Shaw, Leslie M., Sarkozi, Laszlo, Mullins, Richard, Pirsch, John, MacFarlane, Gordon, Scheller, Dan, Ersfeld, Diana, Frick, Mary, Fitzsimmons, William E., Virji, Mohammed, Jain, Ashok, Brayman, Kenneth L., Shaked, Abraham

“…The relationship between the dose of tacrolimus, trough tacrolimus blood concentration, and selected clinical endpoints (acute rejection, nephrotoxicity, and…”
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Tacrolimus (FK506) and sirolimus (rapamycin) in combination are not antagonistic but produce extended graft survival in cardiac transplantation in the rat by MINH DIEM VU, QI, S, XU, D, WU, J, FITZSIMMONS, W. E, SEHGAL, S. N, DUMONT, L, BUSQUE, S, DALOZE, P, CHEN, H

“…Combined use of tacrolimus (FK506) with sirolimus (rapamycin [RAPA]) was examined in a model of vascularized heart allograft in the rat. For prevention of…”
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Effect of tacrolimus (FK506) and sirolimus (rapamycin) mono- and combination therapy in prolongation of renal allograft survival in the monkey by SHIJIE QI, DASHENG XU, HUIFANG CHEN, JUNZHENG PENG, MINH DIEM VU, JIANGPING WU, BEKERSKY, I, FITZSIMMONS, W. E, PEETS, J, SEHGAL, S, DALOZE, P

“…Our previous studies confirmed that tacrolimus (FK506) and sirolimus [rapamycin (RAPA)], in combination, are not antagonistic but are synergistic in the…”
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Demographic Considerations in Tacrolimus Pharmacokinetics by Fitzsimmons, W.E, Bekersky, I, Dressler, D, Raye, K, Hodosh, E, Mekki, Q

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FK506 in Combination With Methotrexate for the Prevention of Graft-Versus-Host Disease After Marrow Transplantation From Matched Unrelated Donors by Nash, Richard A., Pineiro, Luis A., Storb, Rainer, Deeg, H.Joachim, Fitzsimmons, William E., Furlong, Terry, Hansen, John A., Gooley, Ted, Maher, Rochelle M., Martin, Paul, McSweeney, Peter A., Sullivan, Keith M., Anasetti, Claudio, Fay, Joseph W.

“…The safety and potential efficacy of FK506 in combination with a short course of methotrexate (MTX) for the prevention of acute graft-versus-host disease…”
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4-Aminopyridine in multiple sclerosis : prolonged administration by STEFOSKI, D, DAVIS, F. A, FITZSIMMONS, W. E, LUSKIN, S. S, RUSH, D. J, PARKHURST, G. W

“…In an earlier study, we demonstrated efficacy of single oral doses of 4-aminopyridine (4-AP) in improving motor and visual signs in multiple sclerosis (MS)…”
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Combined effect of rapamycin and FK 506 in prolongation of small bowel graft survival in the mouse by Chen, H., Qi, S., Xu, D., Fitzsimmons, W.E., Bekersky, I., Sehgal, S.N., Daloze, P.

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Compromised kidney graft rejection response in vervet monkeys after withdrawal of immunosuppressants tacrolimus and sirolimus by HUIFANG CHEN, JUNZHENG PENG, BEKERSKY, I, PEETS, J, SEHGAL, S. N, JIANGPING WU, HONGYU LUO, LOUBEAU, M, XIAOCHUN WAN, DASHENG XU, SHIJIE QI, MINH DIEM VU, DALOZE, P, FITZSIMMONS, W. E

“…In nonprimates, organ allografts are often not rejected after withdrawal of immunosuppression. In this study, we examined whether such a phenomenon also occurs…”
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FK 506 and Rapamycin in Combination Are Not Antagonistic but Produce Extended Small Bowel Graft Survival in the Mouse by Chen, H, Qi, S, Xu, D, Vu, D.M, Fitzsimmons, W.E, Bekersky, I, Peets, J, Sehgal, S.N, Daloze, P

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Pharmacokinetics and in vivo activity of liposome-encapsulated gentamicin by SWENSON, C. E, STEWART, K. A, HAMMETT, J. L, FITZSIMMONS, W. E, GINSBERG, R. S

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Glucocorticoids fail to enhance the effect of FK506 and methotrexate in prevention of graft-versus-host disease after DLA-nonidentical, unrelated marrow transplantation by YU, C, SEIDEL, K, FITZSIMMONS, W. E, SALE, G, STORB, R

“…Several steroid receptor-associated heat shock proteins can bind to FK506 as immunophilins. This has led to speculation that the steroid receptor and…”
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Cyclosporine monitoring improves graft-versus-host disease prophylaxis after bone marrow transplantation by Ghalie, R, Fitzsimmons, W E, Weinstein, A, Manson, S, Kaizer, H

“…The principal objective of this study was to determine whether a relationship exists between trough cyclosporine concentrations measured by HPLC and the…”
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Cortical blindness: a rare complication of cyclosporine therapy by Ghalie, R, Fitzsimmons, W E, Bennett, D, Kaizer, H

“…We report a bone marrow transplant patient who developed a reversible episode of cortical blindness, a rare complication of cyclosporine therapy. We review…”
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Randomized trial of tacrolimus plus mycophenolate mofetil or azathioprine versus cyclosporine oral solution (modified) plus mycophenolate mofetil after cadaveric kidney transplantation : Results at 2 years by AHSAN, Nasimul, JOHNSON, Christopher, SORENSEN, John, MULLOY, Laura, LIGHT, Jimmy, CORWIN, Claudia, DANOVITCH, Gabriel, WACHS, Michael, VANVELDHUISEN, Paul, SALM, Kim, TOLZMAN, Diane, FITZSIMMONS, William E, GONWA, Thomas, HALLORAN, Philip, STEGALL, Mark, HARDY, Mark, METZGER, Robert, SHIELD, Charles III, ROCHER, Leslie, SCANDLING, John

“…A previous report described the 1-year results of a prospective, randomized trial designed to investigate the optimal combination of immunosuppressants in…”
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Consensus document: therapeutic monitoring of tacrolimus (FK-506) by Jusko, W J, Thomson, A W, Fung, J, McMaster, P, Wong, S H, Zylber-Katz, E, Christians, U, Winkler, M, Fitzsimmons, W E, Lieberman, R

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Tacrolimus (FK506) and methotrexate regimens to prevent graft-versus-host disease after unrelated dog leukocyte antigen (DLA) nonidentical marrow transplantation by Yu, C, Storb, R, Deeg, H J, Graham, T C, Scheuning, F G, Huss, R, Seidel, K, Fitzsimmons, W E

“…We previously reported an synergism between methotrexate and tacrolimus (FK506) in preventing graft-versus-host disease (GVHD) in dogs given DLA-nonidentical…”
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Synergistic effects of malononitrilamides (FK778, FK779) with tacrolimus (FK506) in prevention of acute heart and kidney allograft rejection and reversal of ongoing heart allograft rejection in the rat by BILOLO, Kupa K, JUN OUYANG, HUIFANG CHEN, XIANG WANG, SHENGYUN ZHU, WENLEI JIANG, SHIJIE QI, DASHENG XU, HEBERT, Marie J, BEKERSKY, Ihor, FITZSIMMONS, William E

“…The effects of tacrolimus (FK506) and malononitrilamides (MNA) (FK778 and FK779) monotherapy and combination therapy were examined in prevention of acute heart…”
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