Search Results - "FISHER, E"
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The master role of microphthalmia-associated transcription factor in melanocyte and melanoma biology
Published in Laboratory investigation (01-06-2017)“…Certain transcription factors have vital roles in lineage development, including specification of cell types and control of differentiation…”
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2
The melanoma revolution: From UV carcinogenesis to a new era in therapeutics
Published in Science (American Association for the Advancement of Science) (21-11-2014)“…Melanoma, the deadliest form of skin cancer, is an aggressive disease that is rising in incidence. Although melanoma is a historically treatment-resistant…”
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3
MITF and UV responses in skin: From pigmentation to addiction
Published in Pigment cell and melanoma research (01-03-2019)“…Ultraviolet radiation (UVR) has numerous effects on skin, including DNA damage, tanning, vitamin D synthesis, carcinogenesis, and immunomodulation…”
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4
Exercise-enhanced neuroplasticity targeting motor and cognitive circuitry in Parkinson's disease
Published in Lancet neurology (01-07-2013)“…Summary Exercise interventions in individuals with Parkinson's disease incorporate goal-based motor skill training to engage cognitive circuitry important in…”
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5
Skin pigmentation and its control: From ultraviolet radiation to stem cells
Published in Experimental dermatology (01-04-2021)“…In the light of substantial discoveries in epithelial and hair pigmentation pathophysiology, this review summarizes the current understanding of skin…”
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6
Melanoma: from mutations to medicine
Published in Genes & development (01-06-2012)“…Melanoma is often considered one of the most aggressive and treatment-resistant human cancers. It is a disease that, due to the presence of melanin pigment,…”
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7
Intratumoral Activity of the CXCR3 Chemokine System Is Required for the Efficacy of Anti-PD-1 Therapy
Published in Immunity (Cambridge, Mass.) (18-06-2019)“…Despite compelling rates of durable clinical responses to programmed cell death-1 (PD-1) blockade, advances are needed to extend these benefits to resistant…”
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8
Speech and Language: Translating the Genome
Published in Trends in genetics (01-09-2017)“…Investigation of the biological basis of human speech and language is being transformed by developments in molecular technologies, including high-throughput…”
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9
Very Strong Atmospheric Methane Growth in the 4 Years 2014–2017: Implications for the Paris Agreement
Published in Global biogeochemical cycles (01-03-2019)“…Atmospheric methane grew very rapidly in 2014 (12.7 ± 0.5 ppb/year), 2015 (10.1 ± 0.7 ppb/year), 2016 (7.0 ± 0.7 ppb/year), and 2017 (7.7 ± 0.7 ppb/year), at…”
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10
Evolution of language: Lessons from the genome
Published in Psychonomic bulletin & review (01-02-2017)“…The post-genomic era is an exciting time for researchers interested in the biology of speech and language. Substantive advances in molecular methodologies have…”
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11
ALS phenotypes with mutations in CHMP2B (charged multivesicular body protein 2B)
Published in Neurology (26-09-2006)“…Mutation in the CHMP2B gene has been implicated in frontotemporal dementia. The authors screened CHMP2B in patients with ALS and several cohorts of control…”
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12
Nothing Regular about the Regulins: Distinct Functional Properties of SERCA Transmembrane Peptide Regulatory Subunits
Published in International journal of molecular sciences (18-08-2021)“…The sarco-endoplasmic reticulum calcium ATPase (SERCA) is responsible for maintaining calcium homeostasis in all eukaryotic cells by actively transporting…”
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13
The varieties of contemplative experience: A mixed-methods study of meditation-related challenges in Western Buddhists
Published in PloS one (24-05-2017)“…Buddhist-derived meditation practices are currently being employed as a popular form of health promotion. While meditation programs draw inspiration from…”
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14
The ups and downs of low‐carbohydrate diets in the management of Type 1 diabetes: a review of clinical outcomes
Published in Diabetic medicine (01-03-2019)“…Dietary management has been a mainstay of care in Type 1 diabetes since before the discovery of insulin when severe carbohydrate restriction was advocated. The…”
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15
Endogenous Retrotransposition Activates Oncogenic Pathways in Hepatocellular Carcinoma
Published in Cell (28-03-2013)“…LINE-1 (L1) retrotransposons are mobile genetic elements comprising ∼17% of the human genome. New L1 insertions can profoundly alter gene function and cause…”
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16
A set of regulatory genes co-expressed in embryonic human brain is implicated in disrupted speech development
Published in Molecular psychiatry (01-07-2019)“…Genetic investigations of people with impaired development of spoken language provide windows into key aspects of human biology. Over 15 years after FOXP2 was…”
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The roles of microphthalmia-associated transcription factor and pigmentation in melanoma
Published in Archives of biochemistry and biophysics (01-12-2014)“…•The role of MITF and its targets in melanoma is reviewed.•The role of pigmentation in melanoma is discussed.•Regulation of MITF is reviewed. MITF and…”
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18
MITF: master regulator of melanocyte development and melanoma oncogene
Published in Trends in molecular medicine (01-09-2006)“…Microphthalmia-associated transcription factor (MITF) acts as a master regulator of melanocyte development, function and survival by modulating various…”
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19
On the other hand: including left-handers in cognitive neuroscience and neurogenetics
Published in Nature reviews. Neuroscience (01-03-2014)“…Left-handers are often excluded from neuroscience and neurogenetics studies in order to reduce variance in the data. In this Perspective, Willems et al …”
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Revised Recommendations of the Consortium of MS Centers Task Force for a Standardized MRI Protocol and Clinical Guidelines for the Diagnosis and Follow-Up of Multiple Sclerosis
Published in American journal of neuroradiology : AJNR (01-03-2016)“…An international group of neurologists and radiologists developed revised guidelines for standardized brain and spinal cord MR imaging for the diagnosis and…”
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