Search Results - "FISCHER, Edgar G"

Nuclear Morphology and the Biology of Cancer Cells by Fischer, Edgar G.

“…Background: For more than a century, diagnostic pathologists have used morphologic abnormalities of the nucleus as essential diagnostic features to distinguish…”
Get full text

Localized Breast Amyloidosis Associated with Sjörgren Syndrome by Fischer, Edgar G.

“…Sjörgren syndrome is a systemic autoimmune disease that is rarely associated with amyloid deposits, and in most reported cases, these deposits are localized to…”
Get full text

Prostate field cancerization: deregulated expression of macrophage inhibitory cytokine 1 (MIC-1) and platelet derived growth factor A (PDGF-A) in tumor adjacent tissue by Jones, Anna C, Antillon, Kresta S, Jenkins, Shannon M, Janos, Sara N, Overton, Heidi N, Shoshan, Dor S, Fischer, Edgar G, Trujillo, Kristina A, Bisoffi, Marco

“…Prostate field cancerization denotes molecular alterations in histologically normal tissues adjacent to tumors. Such alterations include deregulated protein…”
Get full text

Lapatinib and potential prognostic value of EGFR mutations in a Gynecologic Oncology Group phase II trial of persistent or recurrent endometrial cancer by Leslie, Kimberly K, Sill, Michael W, Lankes, Heather A, Fischer, Edgar G, Godwin, Andrew K, Gray, Heidi, Schilder, Russell J, Walker, Joan L, Tewari, Krishnansu, Hanjani, Parviz, Abulafia, Ovadia, Rose, Peter G

“…Abstract Objective A phase II trial was performed to evaluate the efficacy and safety of the tyrosine kinase inhibitor of epidermal growth factor receptor…”
Get full text

A phase II evaluation of lapatinib in the treatment of persistent or recurrent epithelial ovarian or primary peritoneal carcinoma: A gynecologic oncology group study by Garcia, Agustin A, Sill, Michael W, Lankes, Heather A, Godwin, Andrew K, Mannel, Robert S, Armstrong, Deborah K, Carolla, Robert L, Liepman, Marcia K, Spirtos, Nick M, Fischer, Edgar G, Leslie, Kimberly K

“…Abstract Objective Activation and dimerization of the ERBB family play a role in the pathogenesis and progression of ovarian cancer. We conducted a phase II…”
Get full text

Two Rare Cases of Paratubal Leydig Cell Nodules: Clinical Relevance and Debated Terminology of a Noteworthy Incidentaloma by Fischer, Edgar G

“…Cells with cytologic and immunohistochemical features of Leydig cells are normally present in the ovary and the ovarian hilum, are testosterone-producing, and…”
Get full text

Duodenal Pyogenic Granuloma by Paleti, Swathi, Fischer, Edgar G., Rustagi, Tarun

Get full text

Fabry disease: a morphologic study of 11 cases by Fischer, Edgar G, Moore, Michael J, Lager, Donna J

“…Fabry disease is a metabolic disorder caused by the genetic deficiency of alpha-galactosidase A. Deposition of glycosphingolipids in podocytes, endothelial…”
Get full text

HPV-associated carcinosarcoma of the anal canal: A rare case provides insight into the pathogenesis of these biphasic neoplasms by Fischer, Edgar G., Rai, Vinay K.

Get full text

Malakoplakia of the Endometrium: A Rare Unexpected Disease Raising Clinical Concern for Malignancy by Fischer, Edgar G, Jones, Devin E, Wu, Emily S, Rutledge, Teresa L

“…Malakoplakia is a rare disease that manifests as a histiocytic inflammatory process and most often occurs in the urinary bladder. It is caused by an impaired…”
Get full text

Management of Abnormal Uterine Bleeding and the Pathology of Endometrial Hyperplasia by Espindola, Dana, BS, Kennedy, Kathleen A., MD, Fischer, Edgar G., MD, PhD

“…There are no screening tests for endometrial carcinoma, and patients typically present with abnormal uterine bleeding. This article discusses the…”
Get full text

Florid Mesothelial Hyperplasia Associated with Abdominal Wall Endometriosis Mimicking Invasive Carcinoma by Fischer, Edgar G., Agarwal, Shweta

“…Florid mesothelial hyperplasia typically occurs in the pelvis, abdomen, or chest associated with an underlying neoplastic or inflammatory process. These…”
Get full text

Perinuclear dot-like cytokeratin 20 staining in small cell neuroendocrine carcinoma of the ovary (pulmonary-type) by Rund, Chad R, Fischer, Edgar G

“…Primary ovarian small cell carcinomas are rare tumors that are subclassified into the hypercalcemic (HT) and the pulmonary type (PT), and each tumor type has…”
Get full text

A Deep Learning Convolutional Neural Network Can Differentiate Between Helicobacter Pylori Gastritis and Autoimmune Gastritis With Results Comparable to Gastrointestinal Pathologists by Franklin, Michael M, Schultz, Fred A, Tafoya, Marissa A, Kerwin, Audra A, Broehm, Cory J, Fischer, Edgar G, Gullapalli, Rama R, Clark, Douglas P, Hanson, Joshua A, Martin, David R

“…Pathology studies using convolutional neural networks (CNNs) have focused on neoplasms, while studies in inflammatory pathology are rare. We previously…”
Get full text

Unusual survival of an adult with pleuropulmonary blastoma and neurofibromatosis by Zuker, Noah B., MD, Dietl, Charles A., MD, Kenna, Sherry, RN, Fischer, Edgar G., MD, PhD, Gardner, David, MD

Get full text

Histologic Effects of Medroxyprogesterone Acetate on Endometrioid Endometrial Adenocarcinoma: A Gynecologic Oncology Group Study by Zaino, Richard J, Brady, William E, Todd, William, Leslie, Kimberly, Fischer, Edgar G, Horowitz, Neil S, Mannel, Robert S, Walker, Joan L, Ivanovic, Marina, Duska, Linda R

“…Progestins have been used in the treatment of recurrent endometrial adenocarcinoma for almost 50 yr. Some endometrial carcinomas respond to hormonal therapy,…”
Get full text

Altered protein levels in the isolated extracellular matrix of failing human hearts with dilated cardiomyopathy by DeAguero, Joshua L, McKown, Elizabeth N, Zhang, Liwen, Keirsey, Jeremy, Fischer, Edgar G, Samedi, Von G, Canan, Benjamin D, Kilic, Ahmet, Janssen, Paul M.L, Delfín, Dawn A

“…Abstract Dilated cardiomyopathy is associated with extensive pathological cardiac remodeling and involves numerous changes in the protein expression profile of…”
Get full text

A Role for Tissue Factor in Cell Adhesion and Migration Mediated by Interaction with Actin-Binding Protein 280 by Ott, Ilka, Fischer, Edgar G., Miyagi, Yohei, Mueller, Barbara M., Ruf, Wolfram

“…Tissue factor (TF), the protease receptor initiating the coagulation system, functions in vascular development, angiogenesis, and tumor cell metastasis by…”
Get full text

Early growth response 1 and fatty acid synthase expression is altered in tumor adjacent prostate tissue and indicates field cancerization by Jones, Anna C., Trujillo, Kristina A., Phillips, Genevieve K., Fleet, Trisha M., Murton, Jaclyn K., Severns, Virginia, Shah, Satyan K., Davis, Michael S., Smith, Anthony Y., Griffith, Jeffrey K., Fischer, Edgar G., Bisoffi, Marco

“…BACKGROUND Field cancerization denotes the occurrence of molecular alterations in histologically normal tissues adjacent to tumors. In prostate cancer,…”
Get full text

Organ-wide telomeric status in diseased and disease-free prostatic tissues by Heaphy, Christopher M., Fleet, Trisha M., Treat, Eric G., Lee, Sang-Joon, Smith, Anthony Y., Davis, Michael S., Griffith, Jeffrey K., Fischer, Edgar G., Bisoffi, Marco

“…Background Telomere attrition occurs early in the development of prostatic adenocarcinoma. However, little is known about either telomere status in benign…”
Get full text