Search Results - "FIRBANK, Michael J"

Gray and white matter imaging: A biomarker for cognitive impairment in early Parkinson's disease? by Duncan, Gordon W., Firbank, Michael J., Yarnall, Alison J., Khoo, Tien K., Brooks, David J., Barker, Roger A., Burn, David J., O'Brien, John T.

“…ABSTRACT Background The aim of this work was to investigate the cortical and white matter changes that underlie cognitive impairment in patients with incident…”
Get full text

Consecutive sessions of transcranial direct current stimulation do not remediate visual hallucinations in Lewy body dementia: a randomised controlled trial by Elder, Greg J, Colloby, Sean J, Firbank, Michael J, McKeith, Ian G, Taylor, John-Paul

“…Complex visual hallucinations are common in Lewy body dementia (LBD) and can cause significant patient and caregiver distress. Current treatments are primarily…”
Get full text

Effects of transcranial direct current stimulation upon attention and visuoperceptual function in Lewy body dementia: a preliminary study by Elder, Greg J, Firbank, Michael J, Kumar, Hrishikesh, Chatterjee, Payel, Chakraborty, Titas, Dutt, Alakananda, Taylor, John-Paul

“…Individuals with Lewy body dementia (LBD) typically exhibit impairments in attentional and executive function. Current pharmacological treatments have limited…”
Get more information

Relationship between progression of brain white matter changes and late-life depression: 3-year results from the LADIS study by Firbank, Michael J., Teodorczuk, Andrew, Van Der Flier, Wiesje M., Gouw, Alida A., Wallin, Anders, Erkinjuntti, Timo, Inzitari, Domenico, Wahlund, Lars-Olof, Pantoni, Leonardo, Poggesi, Anna, Pracucci, Giovanni, Langhorne, Peter, O'Brien, John T.

“…Brain white matter changes (WMC) and depressive symptoms are linked, but the directionality of this association remains unclear. To investigate the…”
Get full text

Investigation of structural brain changes in Charles Bonnet Syndrome by Firbank, Michael J., daSilva Morgan, Katrina, Collerton, Daniel, Elder, Greg J., Parikh, Jehill, Olsen, Kirsty, Schumacher, Julia, ffytche, Dominic, Taylor, John-Paul

“…•Reduced grey matter in the occipital cortex in eye disease groups.•Widespread altered diffusivity in eye disease groups.•No cortical or white matter changes…”
Get full text

Functional Connectivity in Late-Life Depression Using Resting-State Functional Magnetic Resonance Imaging by Kenny, Eva R., M.Res, O’Brien, John T., D.M., F.R.C.Psych, Cousins, David A., M.R.C.Psych, Richardson, Jonathan, M.R.C.Psych, Thomas, Alan J., Ph.D., M.R.C.Psych, Firbank, Michael J., Ph.D, Blamire, Andrew M., Ph.D

“…Objective: To investigate whether there are differences in brain connectivity in late-life depression (LLD) and nondepressed subjects using the left and right…”
Get full text

Relationship Between Cognition, Magnetic Resonance White Matter Hyperintensities, and Cardiovascular Autonomic Changes in Late-Life Depression by Vasudev, Akshya, Ph.D, Saxby, Brian K., Ph.D, O'Brien, John T., F.R.C.Psych., D.M, Colloby, Sean J., Ph.D, Firbank, Michael J., Ph.D, Brooker, Helen, Ph.D, Wesnes, Keith, Ph.D, Thomas, Alan J., Ph.D., M.R.C.Psych

“…Objectives To explore the relationship between specific aspects of cognition, white matter hyperintensities (WMHs), and cardiovascular autonomic parameters in…”
Get full text

Cortical thickness and VBM-DARTEL in late-life depression by Colloby, Sean J, Firbank, Michael J, Vasudev, Akshya, Parry, Steve W, Thomas, Alan J, O'Brien, John T

“…Abstract Background Numerous studies have revealed structural brain changes in late life depression, mainly in white matter or whole lobes with few focussing…”
Get full text

Relationship of orthostatic blood pressure to white matter hyperintensities and subcortical volumes in late-life depression by Colloby, Sean J., Vasudev, Akshya, O'Brien, John T., Firbank, Michael J., Parry, Steve W., Thomas, Alan J.

“…Structural brain abnormalities are associated with late-life major depression, with numerous studies reporting increased white matter hyperintensities (WMH)…”
Get full text

Testing Visual Perception in Dementia with Lewy Bodies and Alzheimer Disease by Wood, Joshua S., B.Sc, Firbank, Michael J., Ph.D, Mosimann, Urs P., M.D., Ph.D, Watson, Rosie, F.R.A.C.P, Barber, Robert, M.D, Blamire, Andrew M., Ph.D, O’Brien, John T., D.M

“…Objective Visuoperceptual deficits are common in dementia with Lewy bodies (DLB) and Alzheimer disease (AD). Testing visuoperception in dementia is complicated…”
Get full text

Medial temporal atrophy rather than white matter hyperintensities predict cognitive decline in stroke survivors by Firbank, Michael J, Burton, Emma J, Barber, Robert, Stephens, Sally, Kenny, Rose Anne, Ballard, Clive, Kalaria, Raj N, O’Brien, John T

“…Abstract Stroke is an important risk factor for dementia, but the exact mechanisms involved in cognitive decline remain unclear. In this study, we related…”
Get full text

Structural Brain Correlates of Attention Dysfunction in Lewy Body Dementias and Alzheimer's Disease by Cromarty, Ruth A, Schumacher, Julia, Graziadio, Sara, Gallagher, Peter, Killen, Alison, Firbank, Michael J, Blamire, Andrew, Kaiser, Marcus, Thomas, Alan J, O'Brien, John T, Peraza, Luis R, Taylor, John-Paul

“…Lewy body dementia (LBD) and Alzheimer's disease (AD) are common forms of dementia that have different clinical profiles but are both commonly associated with…”
Get full text

Extraocular muscle atrophy and central nervous system involvement in chronic progressive external ophthalmoplegia by Yu-Wai-Man, Cynthia, Smith, Fiona E, Firbank, Michael J, Guthrie, Grant, Guthrie, Stuart, Gorman, Grainne S, Taylor, Robert W, Turnbull, Douglass M, Griffiths, Philip G, Blamire, Andrew M, Chinnery, Patrick F, Yu-Wai-Man, Patrick

“…Chronic progressive external ophthalmoplegia (CPEO) is a classical mitochondrial ocular disorder characterised by bilateral progressive ptosis and…”
Get full text

Pioglitazone Decreases Fasting and Postprandial Endogenous Glucose Production in Proportion to Decrease in Hepatic Triglyceride Content by RAVIKUMAR, Balasubramanian, GERRARD, Jean, DALLA MAN, Chiara, FIRBANK, Michael J, LANE, Annette, ENGLISH, Philip T, COBELLI, Claudio, TAYLOR, Roy

“…Pioglitazone Decreases Fasting and Postprandial Endogenous Glucose Production in Proportion to Decrease in Hepatic Triglyceride Content Balasubramanian…”
Get full text

Neuroimaging predictors of death and dementia in a cohort of older stroke survivors by Firbank, Michael J, Allan, Louise M, Burton, Emma J, Barber, Robert, O'Brien, John T, Kalaria, Raj N

“…BackgroundStroke is a risk factor for subsequent death and dementia. Being able to identify subjects at particular risk would be beneficial to inform treatment…”
Get full text

Do obese but metabolically normal women differ in intra-abdominal fat and physical activity levels from those with the expected metabolic abnormalities? A cross-sectional study by Hayes, Louise, Pearce, Mark S, Firbank, Michael J, Walker, Mark, Taylor, Roy, Unwin, Nigel C

“…Obesity remains a major public health problem, associated with a cluster of metabolic abnormalities. However, individuals exist who are very obese but have…”
Get full text

Diffusion Magnetic Resonance Imaging Microstructural Abnormalities in Multiple System Atrophy: A Comprehensive Review by Pasquini, Jacopo, Firbank, Michael J., Ceravolo, Roberto, Silani, Vincenzo, Pavese, Nicola

“…Multiple system atrophy (MSA) is a neurodegenerative disease characterized by autonomic failure, ataxia, and/or parkinsonism. Its prominent pathological…”
Get full text

Relationship between periventricular and deep white matter lesions and depressive symptoms in older people. The LADIS Study by Krishnan, Mani S, O'Brien, John T, Firbank, Michael J, Pantoni, Leonardo, Carlucci, Giovanna, Erkinjuntti, Timo, Wallin, Anders, Wahlund, Lars-Olof, Scheltens, Philip, van Straaten, Elisabeth C.W., Inzitari, Domenico

“…Background Both types of cerebral white matter hyperintensities, periventricular (PVL) and deep white matter lesions (DWML) have been previously associated…”
Get full text

Reduced occipital GABA in Parkinson disease with visual hallucinations by Firbank, Michael J, Parikh, Jehill, Murphy, Nicholas, Killen, Alison, Allan, Charlotte L, Collerton, Daniel, Blamire, Andrew M, Taylor, John-Paul

“…OBJECTIVETo investigate the relationship between visual hallucinations in Parkinson disease (PD) and levels of γ-aminobutyric acid (GABA) in the primary visual…”
Get full text

Long reaction times are associated with delayed brain activity in lewy body dementia by Firbank, Michael J, O'Brien, John T, Taylor, John Paul

“…A significant symptom of Lewy body dementia (LBD) is slow cognitive processing or bradyphrenia. In a previous fMRI task-based study, we found slower responses…”
Get full text