Search Results - "FINN, Ronald D"

PET imaging of soluble yttrium-86-labeled carbon nanotubes in mice by McDevitt, Michael R, Chattopadhyay, Debjit, Jaggi, Jaspreet S, Finn, Ronald D, Zanzonico, Pat B, Villa, Carlos, Rey, Diego, Mendenhall, Juana, Batt, Carl A, Njardarson, Jon T, Scheinberg, David A

“…The potential medical applications of nanomaterials are shaping the landscape of the nanobiotechnology field and driving it forward. A key factor in…”
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Phase I Study of Targeted Radioimmunotherapy for Leptomeningeal Cancers Using Intra-Ommaya 131-I-3F8 by KRAMER, Kim, HUMM, John L, WOLDEN, Suzanne L, LARSON, Steven M, CHEUNG, Nai-Kong V, SOUWEIDANE, Mark M, ZANZONICO, Pat B, DUNKEL, Ira J, GERALD, William L, KHAKOO, Yasmin, YEH, Samuel D, YEUNG, Henry W, FINN, Ronald D

“…Tumors metastasizing to the CNS and leptomeninges (LM) are associated with significant mortality. We tested the toxicity, pharmacokinetics, and dosimetry of…”
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Imaging of HSV-tk Reporter Gene Expression: Comparison Between [18F]FEAU, [18F]FFEAU, and Other Imaging Probes by Miyagawa, Tadashi, Gogiberidze, George, Serganova, Inna, Cai, Shangde, Balatoni, Julius A, Thaler, Howard T, Ageyeva, Lyudmila, Pillarsetty, Nagavarakishore, Finn, Ronald D, Blasberg, Ronald G

“…Herpes virus type 1 thymidine kinase (HSV1-tk) and the mutant HSV1-sr39tk are the 2 most widely used "reporter genes" for radiotracer-based imaging. Two…”
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Targeted α particle immunotherapy for myeloid leukemia by Jurcic, Joseph G., Larson, Steven M., Sgouros, George, McDevitt, Michael R., Finn, Ronald D., Divgi, Chaitanya R., Ballangrud, Åse M., Hamacher, Klaus A., Ma, Dangshe, Humm, John L., Brechbiel, Martin W., Molinet, Roger, Scheinberg, David A.

“…Unlike β particle–emitting isotopes, α emitters can selectively kill individual cancer cells with a single atomic decay. HuM195, a humanized anti-CD33…”
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Assessment of regional tumor hypoxia using 18F-fluoromisonidazole and 64Cu(II)-diacetyl-bis(N4-methylthiosemicarbazone) positron emission tomography: Comparative study featuring microPET imaging, Po2 probe measurement, autoradiography, and fluorescent microscopy in the R3327-AT and FaDu rat tumor models by O'Donoghue, Joseph A, Zanzonico, Pat, Pugachev, Andrei, Wen, Bixiu, Smith-Jones, Peter, Cai, Shangde, Burnazi, Eva, Finn, Ronald D, Burgman, Paul, Ruan, Shutian, Lewis, Jason S, Welch, Michael J, Ling, C Clifton, Humm, John L

“…To compare two potential positron emission tomography (PET) tracers of tumor hypoxia in an animal model. The purported hypoxia imaging agents…”
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An α-particle emitting antibody ([213Bi]J591) for radioimmunotherapy of prostate cancer by MCDEVITT, Michael R, BARENDSWAARD, Els, GEERLINGS, Maurits W, LEE, Mona, BRECHBIEL, Martin W, BANDER, Neil H, CORDON-CARDO, Carlos, SCHEINBERG, David A, MA, Dangshe, LAI, Lawrence, CURCIO, Michael J, SGOUROS, George, BALLANGRUD, Ase M, YANG, Wei-Hong, FINN, Ronald D, PELLEGRINI, Virginia

“…A novel alpha-particle emitting monoclonal antibody construct targeting the external domain of prostate-specific membrane antigen (PSMA) was prepared and…”
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Patient-Specific, 3-Dimensional Dosimetry in Non-Hodgkin's Lymphoma Patients Treated with 131I-anti-B1 Antibody: Assessment of Tumor Dose-Response by Sgouros, George, Squeri, Shannon, Ballangrud, Ase M, Kolbert, Katherine S, Teitcher, Jerrold B, Panageas, Katherine S, Finn, Ronald D, Divgi, Chaitanya R, Larson, Steven M, Zelenetz, Andrew D

“…A comprehensive, SPECT-based, patient-specific 3-dimensional (3D) dosimetry analysis has been performed using 3D-ID, a previously developed software package…”
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Synthesis and Evaluation of [18F] Labeled Pyrimidine Nucleosides for Positron Emission Tomography Imaging of Herpes Simplex Virus 1 Thymidine Kinase Gene Expression by Pillarsetty, Nagavarakishore, Cai, Shangde, Ageyeva, Lyudmila, Finn, Ronald D, Blasberg, Ronald G

“…Synthesis of three novel 2‘-deoxy-2‘-[18F]fluoro-1-β-d-arabinofuranosyluracil derivatives [18F]FPAU, [18F]FBrVAU, and [18F]FTMAU is reported. The compounds…”
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The search for consistency in the manufacture of PET radiopharmaceuticals by Finn, R D

“…Nuclear Medicine is the specialty of medical imaging, which utilizes a variety of radionuclides incorporated into specific compounds for diagnostic imaging and…”
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Radioimmunotherapy with alpha-emitting nuclides by McDevitt, M R, Sgouros, G, Finn, R D, Humm, J L, Jurcic, J G, Larson, S M, Scheinberg, D A

“…This review discusses the application of alpha particle-emitting radionuclides in targeted radioimmunotherapy. It will outline the production and chemistry of…”
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Quantitative imaging of bromine-76 and yttrium-86 with PET: A method for the removal of spurious activity introduced by cascade gamma rays by Beattie, Bradley J., Finn, Ronald D., Rowland, Douglas J., Pentlow, Keith S.

“…Positron Emission Tomography of bromine-76 and yttrium-86 results in the detection of coincident events that are not strictly associated with annihilation…”
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A robotic system for 18F-FMISO PET-guided intratumoral pO2 measurements by Chang, Jenghwa, Wen, Bixiu, Kazanzides, Peter, Zanzonico, Pat, Finn, Ronald D, Fichtinger, Gabor, Ling, C Clifton

“…An image-guided robotic system was used to measure the oxygen tension (pO2) in rodent tumor xenografts using interstitial probes guided by tumor hypoxia PET…”
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Prospective assessment of primary rectal cancer response to preoperative radiation and chemotherapy using 18-fluorodeoxyglucose positron emission tomography by Guillem, J G, Puig-La Calle, Jr, J, Akhurst, T, Tickoo, S, Ruo, L, Minsky, B D, Gollub, M J, Klimstra, D S, Mazumdar, M, Paty, P B, Macapinlac, H, Yeung, H, Saltz, L, Finn, R D, Erdi, Y, Humm, J, Cohen, A M, Larson, S

“…The purpose of this prospective study was to determine the ability of fluorine-18 fluorodeoxyglucose positron emission tomography to assess extent of…”
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A robotic system for ‐FMISO PET‐guided intratumoral measurements by Chang, Jenghwa, Wen, Bixiu, Kazanzides, Peter, Zanzonico, Pat, Finn, Ronald D., Fichtinger, Gabor, Ling, C. Clifton

“…An image‐guided robotic system was used to measure the oxygen tension in rodent tumor xenografts using interstitial probes guided by tumor hypoxia PET images…”
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Alpha-Emitting Bismuth Cyclohexylbenzyl DTPA Constructs of Recombinant Humanized Anti-CD33 Antibodies: Pharmacokinetics, Bioactivity, Toxicity and Chemistry by Nikula, Tuomo K, McDevitt, Michael R, Finn, Ronald D, Wu, Chuanchu, Kozak, Robert W, Garmestani, Kayhan, Brechbiel, M.W, Curcio, Michael J, Pippin, C. Greg, Tiffany-Jones, L, Geerlings, Maurits W., Sr, Apostolidis, Christos, Molinet, Roger, Geerlings, Maurits W., Jr, Gansow, Otto A, Scheinberg, David A

“…The alpha-particle-emitting radionuclides have several physical characteristics that make them attractive candidates for radioimmunotherapy: (a) high linear…”
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Imaging brain tumor proliferative activity with [124I]iododeoxyuridine by BLASBERG, R. G, ROELCKE, U, MISSIMER, J, MAGUIRE, R. P, KOZIOROWSKI, J, KNUST, E. J, FINN, R. D, LEENDERS, K. L, WEINREICH, R, BEATTIE, B, VON AMMON, K, YONEKAWA, Y, LANDOLT, H, GUENTHER, I, CROMPTON, N. E. A, VONTOBEL, P

“…Iododeoxyuridine (IUdR) uptake and retention was imaged by positron emission tomography (PET) at 0-48 min and 24 h after administration of 28.0-64.4 MBq…”
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Quantitative Imaging of Iodine-124 with PET by Pentlow, Keith S, Graham, Martin C, Lambrecht, Richard M, Daghighian, Farhad, Bacharach, Stephen L, Bendriem, Bernard, Finn, Ronald D, Jordan, Kurt, Kalaigian, Hovanes, Karp, Joel S, Robeson, William R, Larson, Steven M

“…PET is potentially very useful for the accurate in vivo quantitation of time-varying biological distributions of radiolabeled antibodies over several days. The…”
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Synthesis and in vitro examination of [ 124I]-, [ 125I]- and [ 131I]-2-(4-iodophenylamino) pyrido[2,3- d]pyrimidin-7-one radiolabeled Abl kinase inhibitors by Veach, Darren R., Namavari, Mohammad, Beresten, Tatiana, Balatoni, Julius, Minchenko, Maria, Djaballah, Hakim, Finn, Ronald D., Clarkson, Bayard, Gelovani, Juri G., Bornmann, William G., Larson, Steven M.

“…The pyridopyrimidinones are a potent class of inhibitors of c-Abl kinase and Bcr–Abl kinase, the causative fusion protein in chronic myelogenous leukemia and…”
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Detection of bony metastases of androgen-independent prostate cancer by PET-FDG by Yeh, Samuel D.J., Imbriaco, Massimo, Larson, Steven M., Garza, Dahlia, Zhang, Jia Ju, Kalaigian, Hovanes, Finn, Ronald D., Ready, David, Horowitz, Steven M., Goldsmith, Stanley J., Scher, Howard I.

“…Fourteen F-18 fluorodeoxyglucose (FDG) studies were carried out in 13 patients known to have bony metastases from carcinoma of the prostate. One patient was…”
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Population pharmacokinetics of antifibroblast activation protein monoclonal antibody F19 in cancer patients by Tanswell, Paul, Garin‐Chesa, Pilar, Rettig, Wolfgang J., Welt, Sydney, Divgi, Chaitanya R., Casper, Ephraim S., Finn, Ronald D., Larson, Steven M., Old, Lloyd J., Scott, Andrew M.

“…Aims  The population pharmacokinetics of 131I‐mAbF19, a radiolabelled murine monoclonal antibody against fibroblast activation protein and a potential…”
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