Search Results - "FINK, E"

A hybrid workflow for investigating wide DEM parameter spaces by Forgber, T., Khinast, J.G., Fink, E.

“…Calibration of contact parameters for the DEM approach remains one of the critical obstacles for an accurate description of powder flows. Ideally, such a…”
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Prospective, Multicenter, Controlled Trial of Mobile Stroke Units by Grotta, James C, Yamal, Jose-Miguel, Parker, Stephanie A, Rajan, Suja S, Gonzales, Nicole R, Jones, William J, Alexandrov, Anne W, Navi, Babak B, Nour, May, Spokoyny, Ilana, Mackey, Jason, Persse, David, Jacob, Asha P, Wang, Mengxi, Singh, Noopur, Alexandrov, Andrei V, Fink, Matthew E, Saver, Jeffrey L, English, Joey, Barazangi, Nobl, Bratina, Patti L, Gonzalez, Michael, Schimpf, Brandi D, Ackerson, Kim, Sherman, Carla, Lerario, Mackenzie, Mir, Saad, Im, Jenny, Willey, Josh Z, Chiu, David, Eisshofer, Michael, Miller, Janice, Ornelas, David, Rhudy, James P, Brown, Kevin M, Villareal, Bryan M, Gausche-Hill, Marianne, Bosson, Nichole, Gilbert, Greg, Collins, Sarah Q, Silnes, Kelly, Volpi, Jay, Misra, Vivek, McCarthy, James, Flanagan, Tom, Rao, Chethan P.V, Kass, Joseph S, Griffin, Laura, Rangel-Gutierrez, Nicole, Lechuga, Edgar, Stephenson, Jonathan, Phan, Kenny, Sanders, Yvette, Noser, Elizabeth A, Bowry, Ritvij

“…Mobile stroke units have CT scanners and personnel trained to administer tissue plasminogen activator. In a multicity trial, functional outcomes at 90 days…”
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Nrf2 Amplifies Oxidative Stress via Induction of Klf9 by Zucker, Shoshanna N., Fink, Emily E., Bagati, Archis, Mannava, Sudha, Bianchi-Smiraglia, Anna, Bogner, Paul N., Wawrzyniak, Joseph A., Foley, Colleen, Leonova, Katerina I., Grimm, Melissa J., Moparthy, Kalyana, Ionov, Yurij, Wang, Jianmin, Liu, Song, Sexton, Sandra, Kandel, Eugene S., Bakin, Andrei V., Zhang, Yuesheng, Kaminski, Naftali, Segal, Brahm H., Nikiforov, Mikhail A.

“…Reactive oxygen species (ROS) activate NF-E2-related transcription factor 2 (Nrf2), a key transcriptional regulator driving antioxidant gene expression and…”
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DNA Methylation Regulates Alternative Polyadenylation via CTCF and the Cohesin Complex by Nanavaty, Vishal, Abrash, Elizabeth W., Hong, Changjin, Park, Sunho, Fink, Emily E., Li, Zhuangyue, Sweet, Thomas J., Bhasin, Jeffrey M., Singuri, Srinidhi, Lee, Byron H., Hwang, Tae Hyun, Ting, Angela H.

“…Dysregulation of DNA methylation and mRNA alternative cleavage and polyadenylation (APA) are both prevalent in cancer and have been studied as independent…”
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Orexin/hypocretin system modulates amygdala-dependent threat learning through the locus coeruleus by Sears, Robert M., Fink, Ann E., Wigestrand, Mattis B., Farb, Claudia R., de Lecea, Luis, LeDoux, Joseph E.

“…Survival in a dangerous environment requires learning about stimuli that predict harm. Although recent work has focused on the amygdala as the locus of…”
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Microphthalmia-associated transcription factor suppresses invasion by reducing intracellular GTP pools by Bianchi-Smiraglia, A, Bagati, A, Fink, E E, Moparthy, S, Wawrzyniak, J A, Marvin, E K, Battaglia, S, Jowdy, P, Kolesnikova, M, Foley, C E, Berman, A E, Kozlova, N I, Lipchick, B C, Paul-Rosner, L M, Bshara, W, Ackroyd, J J, Shewach, D S, Nikiforov, M A

“…Melanoma progression is associated with increased invasion and, often, decreased levels of microphthalmia-associated transcription factor (MITF). Accordingly,…”
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Pharmacological targeting of guanosine monophosphate synthase suppresses melanoma cell invasion and tumorigenicity by Bianchi-Smiraglia, A, Wawrzyniak, J A, Bagati, A, Marvin, E K, Ackroyd, J, Moparthy, S, Bshara, W, Fink, E E, Foley, C E, Morozevich, G E, Berman, A E, Shewach, D S, Nikiforov, M A

“…Malignant melanoma possesses one of the highest metastatic potentials among human cancers. Acquisition of invasive phenotypes is a prerequisite for melanoma…”
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XBP1-KLF9 Axis Acts as a Molecular Rheostat to Control the Transition from Adaptive to Cytotoxic Unfolded Protein Response by Fink, Emily E., Moparthy, Sudha, Bagati, Archis, Bianchi-Smiraglia, Anna, Lipchick, Brittany C., Wolff, David W., Roll, Matthew V., Wang, Jianmin, Liu, Song, Bakin, Andrei V., Kandel, Eugene S., Lee, Ann-Hwee, Nikiforov, Mikhail A.

“…Transcription factor XBP1s, activated by endoplasmic reticulum (ER) stress in a dose-dependent manner, plays a central role in adaptive unfolded protein…”
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Cerebrovascular Disease Incidence, Characteristics, and Outcomes in Patients Initiating Dialysis: The Choices for Healthy Outcomes in Caring for ESRD (CHOICE) Study by Sozio, Stephen M., MD, MHS, Armstrong, Paige A., MHS, Coresh, Josef, MD, PhD, Jaar, Bernard G., MD, MPH, Fink, Nancy E., MPH, Plantinga, Laura C., ScM, Powe, Neil R., MD, MPH, MBA, Parekh, Rulan S., MD, MS

“…Background Stroke is the third most common cause of cardiovascular disease death in patients on dialysis therapy; however, characteristics of cerebrovascular…”
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A Simple, High-Resolution Method for Establishing DNA Binding Affinity and Sequence Selectivity by Boger, Dale L, Fink, Brian E, Brunette, Steven R, Tse, Winston C, Hedrick, Michael P

“…Full details of the development of a simple, nondestructive, and high-throughput method for establishing DNA binding affinity and sequence selectivity are…”
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Paroxysmal Supraventricular Tachycardia and the Risk of Ischemic Stroke by KAMEL, Hooman, ELKIND, Mitchell S. V, BHAVE, Prashant D, NAVI, Babak B, OKIN, Peter M, IADECOLA, Costantino, DEVEREUX, Richard B, FINK, Matthew E

“…It is unknown whether supraventricular arrhythmias other than atrial fibrillation or flutter are associated with stroke. To examine the association between…”
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Association of Residual Urine Output With Mortality, Quality of Life, and Inflammation in Incident Hemodialysis Patients: The Choices for Healthy Outcomes in Caring for End-Stage Renal Disease (CHOICE) Study by Shafi, Tariq, MBBS, MHS, Jaar, Bernard G., MD, MPH, Plantinga, Laura C., ScM, Fink, Nancy E., MPH, Sadler, John H., MD, Parekh, Rulan S., MD, MS, Powe, Neil R., MD, MPH, MBA, Coresh, Josef, MD, MHS, PhD

“…Background Residual kidney function (RKF) is associated with improved survival in peritoneal dialysis patients, but its role in hemodialysis patients is less…”
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Internally ratiometric fluorescent sensors for evaluation of intracellular GTP levels and distribution by Bianchi-Smiraglia, Anna, Rana, Mitra S, Foley, Colleen E, Paul, Leslie M, Lipchick, Brittany C, Moparthy, Sudha, Moparthy, Kalyana, Fink, Emily E, Bagati, Archis, Hurley, Edward, Affronti, Hayley C, Bakin, Andrei V, Kandel, Eugene S, Smiraglia, Dominic J, Feltri, Maria Laura, Sousa, Rui, Nikiforov, Mikhail A

“…The genetically encoded GEVAL sensors allow ratiometric imaging of the spatiotemporal dynamics of cellular GTP levels in living cells. GTP is a major regulator…”
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Systematic review and meta-analysis of the effects of menopause hormone therapy on cognition by Andy, Caroline, Nerattini, Matilde, Jett, Steven, Carlton, Caroline, Zarate, Camila, Boneu, Camila, Fauci, Francesca, Ajila, Trisha, Battista, Michael, Pahlajani, Silky, Christos, Paul, Fink, Matthew E, Williams, Schantel, Brinton, Roberta Diaz, Mosconi, Lisa

“…Despite evidence from preclinical studies suggesting estrogen's neuroprotective effects, the use of menopausal hormone therapy (MHT) to support cognitive…”
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Mitochondrial thioredoxin reductase regulates major cytotoxicity pathways of proteasome inhibitors in multiple myeloma cells by Fink, E E, Mannava, S, Bagati, A, Bianchi-Smiraglia, A, Nair, J R, Moparthy, K, Lipchick, B C, Drokov, M, Utley, A, Ross, J, Mendeleeva, L P, Savchenko, V G, Lee, K P, Nikiforov, M A

“…It is generally accepted that intracellular oxidative stress induced by proteasome inhibitors is a byproduct of endoplasmic reticulum (ER) stress. Here we…”
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Opposing effects of PSD-93 and PSD-95 on long-term potentiation and spike timing-dependent plasticity by Carlisle, Holly J., Fink, Ann E., Grant, Seth G. N., O’Dell, Thomas J.

“…The membrane-associated guanylate kinases (MAGUKs) PSD-95, PSD-93 and SAP102 are thought to have crucial roles in both AMPA receptor trafficking and formation…”
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Mechanical Ventilation for Acute Stroke: A Multi-state Population-Based Study by Lahiri, Shouri, Mayer, Stephan A., Fink, Matthew E., Lord, Aaron S., Rosengart, Axel, Mangat, Halinder S., Segal, Alan Z., Claassen, Jan, Kamel, Hooman

“…Background Mechanical ventilation is frequently performed in patients with ischemic stroke (IS), intracerebral hemorrhage (ICH), and subarachnoid hemorrhage…”
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Fish-like propulsion of an airship with planar membrane dielectric elastomer actuators by Jordi, C, Michel, S, Fink, E

“…The goal of our project is to mimic fish-like movement in air, propelling an airship by undulating its hull and a caudal fin. The activation of the fish-like…”
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Changes in serum calcium, phosphate, and PTH and the risk of death in incident dialysis patients: A longitudinal study by Melamed, M.L., Eustace, J.A., Plantinga, L., Jaar, B.G., Fink, N.E., Coresh, J., Klag, M.J., Powe, N.R.

“…Elevated bone mineral parameters have been associated with mortality in dialysis patients. There are conflicting data about calcium, parathyroid hormone (PTH),…”
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Correlates and Outcomes of Fatigue among Incident Dialysis Patients by Jhamb, Manisha, Argyropoulos, Christos, Steel, Jennifer L, Plantinga, Laura, Wu, Albert W, Fink, Nancy E, Powe, Neil R, Meyer, Klemens B, Unruh, Mark L

“…Fatigue is a debilitating symptom experienced by patients undergoing dialysis, but there is only limited information on its prevalence and its association with…”
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