Search Results - "FINGERLE, Alexander A"
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Intestinal Tumorigenesis Initiated by Dedifferentiation and Acquisition of Stem-Cell-like Properties
Published in Cell (17-01-2013)“…Cell-type plasticity within a tumor has recently been suggested to cause a bidirectional conversion between tumor-initiating stem cells and nonstem cells…”
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2
The role of stroma in pancreatic cancer: diagnostic and therapeutic implications
Published in Nature reviews. Gastroenterology & hepatology (01-08-2012)“…Abundant fibrotic stroma is a typical feature of pancreatic ductal adenocarcinoma (PDAC) in humans. It is becoming clear that this stromal tissue is not just a…”
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3
X-ray Dark-Field Chest Imaging: Qualitative and Quantitative Results in Healthy Humans
Published in Radiology (01-11-2021)“…Background X-ray dark-field radiography takes advantage of the wave properties of x-rays, with a relatively high signal in the lungs due to the many air-tissue…”
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4
Dual-energy CT: a phantom comparison of different platforms for abdominal imaging
Published in European radiology (01-07-2018)“…Objectives Evaluation of imaging performance across dual-energy CT (DECT) platforms, including dual-layer CT (DLCT), rapid-kVp-switching CT (KVSCT) and…”
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Dual-layer spectral computed tomography: Virtual non-contrast in comparison to true non-contrast images
Published in European journal of radiology (01-07-2018)“…To evaluate virtual-non-contrast (VNC) images obtained from clinical triphasic scans with a dual-layer spectral computed tomography system regarding accuracy…”
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Initial Performance Characterization of a Clinical Noise—Suppressing Reconstruction Algorithm for MDCT
Published in American journal of roentgenology (1976) (01-12-2011)“…The number of CT examinations is increasing relatively dramatically, hence the radiation dose of the associated population. Thus, there is a need for efficient…”
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Ultra Low Dose CT Pulmonary Angiography with Iterative Reconstruction
Published in PloS one (09-09-2016)“…Evaluation of a new iterative reconstruction algorithm (IMR) for detection/rule-out of pulmonary embolism (PE) in ultra-low dose computed tomography pulmonary…”
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X-ray dark-field chest imaging for detection and quantification of emphysema in patients with chronic obstructive pulmonary disease: a diagnostic accuracy study
Published in The Lancet. Digital health (01-11-2021)“…Although advanced medical imaging technologies give detailed diagnostic information, a low-dose, fast, and inexpensive option for early detection of…”
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Coronary calcium scoring assessed on native screening chest CT imaging as predictor for outcome in COVID-19: An analysis of a hospitalized German cohort
Published in PloS one (30-12-2020)“…Since the outbreak of the COVID-19 pandemic, a number of risk factors for a poor outcome have been identified. Thereby, cardiovascular comorbidity has a major…”
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10
Optimization of tube voltage in X-ray dark-field chest radiography
Published in Scientific reports (18-06-2019)“…Grating-based X-ray dark-field imaging is a novel imaging modality which has been refined during the last decade. It exploits the wave-like behaviour of…”
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11
Does iterative reconstruction lower CT radiation dose: evaluation of 15,000 examinations
Published in PloS one (26-11-2013)“…Evaluation of 15,000 computed tomography (CT) examinations to investigate if iterative reconstruction (IR) reduces sustainably radiation exposure. Information…”
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Differentiation between blood and iodine in a bovine brain-Initial experience with Spectral Photon-Counting Computed Tomography (SPCCT)
Published in PloS one (25-02-2019)“…To evaluate the accuracy of Spectral Photon-Counting Computed Tomography (SPCCT) in the quantification of iodine concentrations and its potential for the…”
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13
Correlation of image quality parameters with tube voltage in X-ray dark-field chest radiography: a phantom study
Published in Scientific reports (08-07-2021)“…Grating-based X-ray dark-field imaging is a novel imaging modality with enormous technical progress during the last years. It enables the detection of…”
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14
Opposing functions of IKKβ during acute and chronic intestinal inflammation
Published in Proceedings of the National Academy of Sciences - PNAS (30-09-2008)“…NF-κB is a key transcriptional regulator of inflammatory responses, but also controls expression of prosurvival genes, whose products protect tissues from…”
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15
Phase-Contrast Hounsfield Units of Fixated and Non-Fixated Soft-Tissue Samples
Published in PloS one (31-08-2015)“…X-ray phase-contrast imaging is a novel technology that achieves high soft-tissue contrast. Although its clinical impact is still under investigation, the…”
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16
Validation of a low dose simulation technique for computed tomography images
Published in PloS one (23-09-2014)“…Evaluation of a new software tool for generation of simulated low-dose computed tomography (CT) images from an original higher dose scan. Original CT scan data…”
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Imaging liver lesions using grating-based phase-contrast computed tomography with bi-lateral filter post-processing
Published in PloS one (17-01-2014)“…X-ray phase-contrast imaging shows improved soft-tissue contrast compared to standard absorption-based X-ray imaging. Especially the grating-based method seems…”
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Simultaneous dual-contrast multi-phase liver imaging using spectral photon-counting computed tomography: a proof-of-concept study
Published in European radiology experimental (22-12-2017)“…Background To assess the feasibility of dual-contrast spectral photon-counting computed tomography (SPCCT) for liver imaging. Methods We present an SPCCT…”
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Dynamic CT perfusion imaging of the myocardium: a technical note on improvement of image quality
Published in PloS one (09-10-2013)“…To improve image and diagnostic quality in dynamic CT myocardial perfusion imaging (MPI) by using motion compensation and a spatio-temporal filter. Dynamic CT…”
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Dark-field chest X-ray imaging for the assessment of COVID-19-pneumonia
Published in Communications medicine (21-11-2022)“…Background Currently, alternative medical imaging methods for the assessment of pulmonary involvement in patients infected with COVID-19 are sought that…”
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