Search Results - "FILETICI, Patrizia"

Re-entrant DNA gels by Bomboi, Francesca, Romano, Flavio, Leo, Manuela, Fernandez-Castanon, Javier, Cerbino, Roberto, Bellini, Tommaso, Bordi, Federico, Filetici, Patrizia, Sciortino, Francesco

“…DNA is acquiring a primary role in material development, self-assembling by design into complex supramolecular aggregates, the building block of a…”
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DNA-GEL, Novel Nanomaterial for Biomedical Applications and Delivery of Bioactive Molecules by Lattuada, Enrico, Leo, Manuela, Caprara, Debora, Salvatori, Luisa, Stoppacciaro, Antonella, Sciortino, Francesco, Filetici, Patrizia

“…Novel DNA materials promise unpredictable perspectives for applications in cell biology. The realization of DNA-hydrogels built by a controlled association of…”
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Epigenetic Factors and Mitochondrial Biology in Yeast: A New Paradigm for the Study of Cancer Metabolism? by Stoppacciaro, Antonella, Di Vito, Serena, Filetici, Patrizia

“…Bidirectional cross-talk between nuclear and mitochondrial DNA is fundamental for cell homeostasis. Epigenetic mechanisms regulate the inter-organelle…”
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A Novel Histone Acetyltransferase Inhibitor Modulating Gcn5 Network: Cyclopentylidene-[4-(4′-chlorophenyl)thiazol-2-yl)hydrazone by Chimenti, Franco, Bizzarri, Bruna, Maccioni, Elias, Secci, Daniela, Bolasco, Adriana, Chimenti, Paola, Fioravanti, Rossella, Granese, Arianna, Carradori, Simone, Tosi, Federica, Ballario, Paola, Vernarecci, Stefano, Filetici, Patrizia

“…Acetylation is a key modulator of genome accessibility through decondensation of the chromatin structure. The balance between acetylation and opposite…”
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Gcn5 histone acetyltransferase is present in the mitoplasts by Montanari, Arianna, Leo, Manuela, De Luca, Veronica, Filetici, Patrizia, Francisci, Silvia

“…In the Lysine-acetyltransferase Gcn5 (KAT2) is part of the SAGA complex and is responsible for histone acetylation widely or at specific lysines. In this paper…”
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Role of yUbp8 in Mitochondria and Hypoxia Entangles the Finding of Human Ortholog Usp22 in the Glioblastoma Pseudo-Palisade Microlayer by De Luca, Veronica, Leo, Manuela, Cretella, Elisabetta, Montanari, Arianna, Saliola, Michele, Ciaffi, Gabriele, Vecchione, Andrea, Stoppacciaro, Antonella, Filetici, Patrizia

“…KAT Gcn5 and DUB Ubp8 are required for respiration and mitochondria functions in budding yeast, and in this study we show that loss of respiratory activity is…”
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SAGA DUB-Ubp8 Deubiquitylates Centromeric Histone Variant Cse4 by Canzonetta, Claudia, Vernarecci, Stefano, Iuliani, Michele, Marracino, Cristina, Belloni, Claudia, Ballario, Paola, Filetici, Patrizia

“…Aneuploidy, the unbalanced segregation of chromosomes during cell division, is recurrent in many tumors and the cause of birth defects and genetic diseases…”
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Small-Molecule Inhibitors of Histone Acetyltransferase Activity:  Identification and Biological Properties by Mai, Antonello, Rotili, Dante, Tarantino, Domenico, Ornaghi, Prisca, Tosi, Federica, Vicidomini, Caterina, Sbardella, Gianluca, Nebbioso, Angela, Miceli, Marco, Altucci, Lucia, Filetici, Patrizia

“…Starting from a yeast phenotypic screening performed on 21 compounds, we described the identification of two small molecules (9 and 18) able to significantly…”
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CPTH6, a Thiazole Derivative, Induces Histone Hypoacetylation and Apoptosis in Human Leukemia Cells by TRISCIUOGLIO, Daniela, RAGAZZONI, Ylenia, BIZZARRI, Bruna, CAVALIERE, Chiara, D'AGNANO, Igea, FILETICI, Patrizia, RICCI-VITIANI, Lucia, RIZZO, Maria Giulia, DEL BUFALO, Donatella, PELOSI, Andrea, DESIDERI, Marianna, CARRADORI, Simone, GABELLINI, Chiara, MARESCA, Giovanna, NESCATELLI, Riccardo, SECCI, Daniela, BOLASCO, Adriana

“…We previously identified novel thiazole derivatives able to reduce histone acetylation and histone acetyltransferase (HAT) activity in yeast. Among these…”
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KAT3B-p300 and H3AcK18/H3AcK14 levels are prognostic markers for kidney ccRCC tumor aggressiveness and target of KAT inhibitor CPTH2 by Cocco, Elisa, Leo, Manuela, Canzonetta, Claudia, Di Vito, Serena, Mai, Antonello, Rotili, Dante, Di Napoli, Arianna, Vecchione, Andrea, De Nunzio, Cosimo, Filetici, Patrizia, Stoppacciaro, Antonella

“…Kidney cancer and clear cell renal carcinoma (ccRCC) are the 16th most common cause of death worldwide. ccRCC is often metastasized at diagnosis, and surgery…”
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Tuning acetylated chromatin with HAT inhibitors: A novel tool for therapy by Vernarecci, Stefano, Tosi, Federica, Filetici, Patrizia

“…Epigenetics, the heritable changes that do not involve DNA sequences, give dynamic propulsion to a static genome and modulate genome accessibility by acting…”
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Gcn5p Plays an Important Role in Centromere Kinetochore Function in Budding Yeast by Vernarecci, Stefano, Ornaghi, Prisca, Bâgu, AnaCristina, Cundari, Enrico, Ballario, Paola, Filetici, Patrizia

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Quinoline Derivative MC1626, a Putative GCN5 Histone Acetyltransferase (HAT) Inhibitor, Exhibits HAT-Independent Activity against Toxoplasma gondii by SMITH, Aaron T, LIVINGSTON, Meredith R, MAI, Antonello, FILETICI, Patrizia, QUEENER, Sherry F, SULLIVAN, William J

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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yeast penta-EF protein Pef1p is involved in cation-dependent budding and cell polarization by Vernarecci, Stefano, Colotti, Gianni, Ornaghi, Prisca, Schiebel, Elmar, Chiancone, Emilia, Filetici, Patrizia

“…Penta-EF-hand (PEF) proteins bind calcium and participate in a variety of calcium-dependent processes in vertebrates. In yeast, intracellular cations regulate…”
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Epigenetics in Rome: Breaking news from the Chromatin Remodeling and Human Disease Workshop by Gaetano, Carlo, Capogrossi, Maurizio C, Fanciulli, Maurizio, Filetici, Patrizia, Piaggio, Giulia

“…In 2009 the Istituto Regina Elena (IRE) and Istituto Dermopatico dell' Immacolata (IDI), joined their efforts to organize the “First IRE Annual Workshop on…”
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Epigenetic regulation in cancer development by Caffarelli, Elisa, Filetici, Patrizia

“…From an operational definition of epigenetic, we move to provide the reader a general but comprehensive description of epigenetic phenomena that often lead to…”
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Epigenetics: a novel tool for early diagnosis and tumor therapy by Filetici, Patrizia

“…Epigenetics, first described by Conrad Waddington, defines how pathways setting a specific phenotype and heritable cellular functions are activated in a DNA…”
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Experimental Evidence of Single-Stranded DNA Adsorption on Multiwalled Carbon Nanotubes by Tardani, Franco, Sarti, Stefano, Sennato, Simona, Leo, Manuela, Filetici, Patrizia, Casciardi, Stefano, Schiavi, Pier Giorgio, Bordi, Federico

“…Noncovalent DNA functionalization is one of the most used routes for the easy dispersion of carbon nanotubes (CNTs) yielding DNA-CNTs complexes with promising…”
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Physical association of the WC-1 photoreceptor and the histone acetyltransferase NGF-1 is required for blue light signal transduction in Neurospora crassa by Brenna, Andrea, Grimaldi, Benedetto, Filetici, Patrizia, Ballario, Paola

“…In Neurospora crassa and other filamentous fungi, light-dependent-specific phenomena are regulated by transcription factors WC-1 and WC-2. In addition to its…”
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Regulation of expression of GLT1, the gene encoding glutamate synthase in Saccharomyces cerevisiae by Valenzuela, L. (Universidad Nacional Autonoma de Mexico.), Ballario, P, Aranda, C, Filetici, P, Gonzalez, A

“…Saccharomyces cerevisiae glutamate synthase (GOGAT) is an oligomeric enzyme composed of three 199-kDa identical subunits encoded by GLT1. In this work, we…”
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