Search Results - "FILES, K"

SARS-CoV-2-specific circulating T follicular helper cells correlate with neutralizing antibodies and increase during early convalescence by Boppana, Sushma, Qin, Kai, Files, Jacob K, Russell, Ronnie M, Stoltz, Regina, Bibollet-Ruche, Frederic, Bansal, Anju, Erdmann, Nathan, Hahn, Beatrice H, Goepfert, Paul A

“…T-cell immunity is likely to play a role in protection against SARS-CoV-2 by helping generate neutralizing antibodies. We longitudinally studied CD4 T-cell…”
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In situ analysis of neuronal injury and neuroinflammation during HIV-1 infection by Honeycutt, Jenna B, Wahl, Angela, Files, Jacob K, League, Alexis F, Yadav-Samudrala, Barkha J, Garcia, J Victor, Fitting, Sylvia

“…Since the introduction of combination antiretroviral therapy (cART) the brain has become an important human immunodeficiency virus (HIV) reservoir due to the…”
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Duration of post-COVID-19 symptoms is associated with sustained SARS-CoV-2-specific immune responses by Files, Jacob K, Sarkar, Sanghita, Fram, Tim R, Boppana, Sushma, Sterrett, Sarah, Qin, Kai, Bansal, Anju, Long, Dustin M, Sabbaj, Steffanie, Kobie, James J, Goepfert, Paul A, Erdmann, Nathan

“…A subset of COVID-19 patients exhibit post-acute sequelae of COVID-19 (PASC), but little is known about the immune signatures associated with these syndromes…”
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Oncogenic role and therapeutic targeting of ABL-class and JAK-STAT activating kinase alterations in Ph-like ALL by Roberts, Kathryn G., Yang, Yung-Li, Payne-Turner, Debbie, Lin, Wenwei, Files, Jacob K., Dickerson, Kirsten, Gu, Zhaohui, Taunton, Jack, Janke, Laura J., Chen, Taosheng, Loh, Mignon L., Hunger, Stephen P., Mullighan, Charles G.

“…New therapies for Philadelphia chromosome–like acute lymphoblastic leukemia (Ph-like ALL) patients are urgently needed. The genetic landscape of Ph-like ALL is…”
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The role of immune activation and antigen persistence in acute and long COVID by Opsteen, Skye, Files, Jacob K, Fram, Tim, Erdmann, Nathan

“…In late 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) triggered the global coronavirus disease 2019 (COVID-19) pandemic. Although most…”
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Use of an In Vitro Pharmacodynamic Model To Derive a Moxifloxacin Regimen That Optimizes Kill of Yersinia pestis and Prevents Emergence of Resistance by LOUIE, A, HEINE, H. S, DRUSANO, G. L, VANSCOY, B, EICHAS, A, FILES, K, FIKES, S, BROWN, D. L, LIU, W, KINZIG-SCHIPPERS, M, SÖRGEL, F

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Photobleaching studies reveal that a single amino acid polymorphism is responsible for the differential binding affinities of linker histone subtypes H1.1 and H1.5 by Flanagan, Thomas W, Files, Jacob K, Casano, Kelsey Rose, George, Eric M, Brown, David T

“…Mammals express six major somatic linker histone subtypes, all of which display dynamic binding to chromatin, characterized by transient binding at a given…”
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Sustained cellular immune dysregulation in individuals recovering from SARS-CoV-2 infection by Files, Jacob K, Boppana, Sushma, Perez, Mildred D, Sarkar, Sanghita, Lowman, Kelsey E, Qin, Kai, Sterrett, Sarah, Carlin, Eric, Bansal, Anju, Sabbaj, Steffanie, Long, Dustin M, Kutsch, Olaf, Kobie, James, Goepfert, Paul A, Erdmann, Nathan

“…SARS-CoV-2 causes a wide spectrum of clinical manifestations and significant mortality. Studies investigating underlying immune characteristics are needed to…”
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Impact of Chronic HIV Infection on Acute Immune Responses to SARS-CoV-2 by Opsteen, Skye, Fram, Tim, Files, Jacob K, Levitan, Emily B, Goepfert, Paul, Erdmann, Nathaniel

“…There is mounting evidence that HIV infection is a risk factor for severe presentations of COVID-19. We hypothesized that the persistent immune activation…”
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Messenger RNA Vaccine Technology: Success for SARS-CoV-2 and Prospects for an HIV-1 Vaccine by Files, Jacob K, Goepfert, Paul A

“…Over the past several years, messenger RNA (mRNA) vaccine has evolved from a term familiar only to vaccine scientists into one easily recognized by much of the…”
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HLA-II-Associated HIV-1 Adaptation Decreases CD4 + T-Cell Responses in HIV-1 Vaccine Recipients by Files, Jacob K, Sterrett, Sarah, Henostroza, Sebastian, Fucile, Christopher, Maroney, Kevin, Fram, Tim, Mallal, Simon, Kalams, Spyros, Carlson, Jonathan, Rosenberg, Alexander, Erdmann, Nathan, Bansal, Anju, Goepfert, Paul A

“…Epitopes with evidence of HLA-II-associated adaptation induce poorly immunogenic CD4 T-cell responses in HIV-positive (HIV ) individuals. Many such escaped CD4…”
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Determining the Impact of Immune Dysregulation on CD4 T Cell Responses to HIV-1 and SARS-CoV-2 by Files, Jacob K

“…CD4+ T cells, often referred to as helper T cells, play a crucial role in the formation of antiviral immune responses following infection and vaccination…”
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The Determination of Humus by Alway, F. J., Files, E. K., Pickney, R. M.

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