Search Results - "FIJNVANDRAAT, K."
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The definition, diagnosis and management of mild hemophilia A: communication from the SSC of the ISTH
Published in Journal of thrombosis and haemostasis (01-12-2018)Get full text
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Setting the stage for individualized therapy in hemophilia: What role can pharmacokinetics play?
Published in Blood reviews (01-07-2018)“…Replacement therapy with clotting factor concentrates (CFC) is the mainstay of treatment in hemophilia. Its widespread application has led to a dramatic…”
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A high rate of post thrombotic complication in pediatric portal vein thrombosis
Published in Thrombosis research (01-11-2023)“…Portal vein thrombosis (PVT) is a rare disease in children and may be complicated by portal hypertension (PH), hepatopulmonary syndrome (HPS) and…”
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Prevalence and Incidence of Non-neutralizing Antibodies in Congenital Hemophilia A- A Systematic Review and Meta-Analysis
Published in Frontiers in immunology (07-05-2020)“…In hemophilia A the presence of non-neutralizing antibodies (NNAs) against Factor VIII (FVIII) may predict the development of neutralizing antibodies…”
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Clinically relevant differences between assays for von Willebrand factor activity
Published in Journal of thrombosis and haemostasis (01-12-2018)“…Essentials It is unclear whether there are differences between von Willebrand factor (VWF) activity assays. We compared the four most used VWF activity assays…”
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Early-Onset Thrombocytopenia in Small-For-Gestational-Age Neonates: A Retrospective Cohort Study
Published in PloS one (13-05-2016)“…Thrombocytopenia is a common finding in small for gestational age (SGA) neonates and is thought to result from a unique pathophysiologic mechanism related to…”
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Mortality caused by intracranial bleeding in non‐severe hemophilia A patients: reply
Published in Journal of thrombosis and haemostasis (01-08-2017)Get full text
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Intensity of factor VIII treatment and the development of inhibitors in non‐severe hemophilia A patients: results of the INSIGHT case–control study
Published in Journal of thrombosis and haemostasis (01-07-2017)“…Essentials Research suggests that intensive treatment episodes may increase the risk to develop inhibitors. We performed an international nested case‐control…”
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Are thrombocytopenia and platelet transfusions associated with major bleeding in preterm neonates? A systematic review
Published in Blood reviews (01-07-2019)“…Over 75% of severely thrombocytopenic preterm neonates receive platelet transfusions to prevent bleeding, but transfusion guidelines are based mainly on expert…”
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CLEC4M and STXBP5 gene variations contribute to von Willebrand factor level variation in von Willebrand disease
Published in Journal of thrombosis and haemostasis (01-06-2015)“…Summary Background von Willebrand factor (VWF) levels in healthy individuals are influenced by variations in genetic loci other than the VWF gene, whose…”
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Inhibitors - genetic and environmental factors
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01-05-2014)“…Summary It is known that a large number of both genetic and environmental factors contribute to the risk of inhibitor development, but underlying pathogenetic…”
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von Willebrand disease and aging: an evolving phenotype
Published in Journal of thrombosis and haemostasis (01-07-2014)“…Summary Background Because the number of elderly von Willebrand disease (VWD) patients is increasing, the pathophysiology of aging in VWD has become…”
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Major differences in clinical presentation, diagnosis and management of men and women with autosomal inherited bleeding disorders
Published in EClinicalMedicine (01-02-2021)“…In recent years, more awareness is raised about sex-specific dilemmas in inherited bleeding disorders. However, no large studies have been performed to assess…”
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Are low-molecular-weight heparins safe and effective in children? A systematic review
Published in Blood reviews (01-01-2019)“…The incidence of venous thromboembolism (VTE) in children is rising. Hence, there is an increasing off-label use of low-molecular-weight heparin (LMWH). There…”
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Intensive peri‐operative use of factor VIII and the Arg593→Cys mutation are risk factors for inhibitor development in mild/moderate hemophilia A
Published in Journal of thrombosis and haemostasis (01-06-2009)“…Background: A severe and challenging complication in the treatment of hemophilia A is the development of inhibiting antibodies (inhibitors) directed towards…”
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In silico evaluation of limited sampling strategies for individualized dosing of extended half-life factor IX concentrates in hemophilia B patients
Published in European journal of clinical pharmacology (01-02-2022)“…Purpose Hemophilia B is a bleeding disorder, caused by a factor IX (FIX) deficiency. Recently, FIX concentrates with extended half-life (EHL) have become…”
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In Vivo T1 of Blood Measurements in Children with Sickle Cell Disease Improve Cerebral Blood Flow Quantification from Arterial Spin-Labeling MRI
Published in American journal of neuroradiology : AJNR (01-09-2016)“…Children with sickle cell disease have low hematocrit and elevated CBF, the latter of which can be assessed with arterial spin-labeling MR imaging…”
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Male gender, school attendance and sports participation are positively associated with health‐related quality of life in children and adolescents with congenital bleeding disorders
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01-05-2018)“…Background This study assesses health‐related quality of life (HRQOL), and variables associated with HRQOL, in children and adolescents with haemophilia and…”
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Measuring anxiety and depression in young adult men with haemophilia using PROMIS
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01-05-2022)Get full text
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