Search Results - "FIDDES, R. J."

Isolation of human anti‐c‐erbB‐2 Fabs from a lymph node‐derived phage display library by CLARK, M. A., HAWKINS, N. J., PAPAIOANNOU, A., FIDDES, R. J., WARD, R. L.

“…An immunoglobulin phage display library constructed from a tumour‐associated pericolic lymph node was panned against the extracellular domain of the…”
Get full text

Inhibition of the MAP kinase cascade blocks heregulin-induced cell cycle progression in T-47D human breast cancer cells by FIDDES, R. J, JANES, P. W, SIVERTSEN, S. P, SUTHERLAND, R. L, MUSGROVE, E. A, DALY, R. J

“…Members of the erbB family of receptor tyrosine kinases are commonly overexpressed in human breast cancer. However, the relative contribution of particular…”
Get full text

A Progesterone Metabolite Stimulates the Release of Gonadotropin-Releasing Hormone from GT1-1 Hypothalamic Neurons via the γ-Aminobutyric Acid Type A Receptor by El-Etr, Martine, Akwa, Yvette, Fiddes, Rodney J., Robel, Paul, Baulieu, Etienne-Emile

“…The reduced progesterone metabolite tetrahydroprogesterone (3α-hydroxy-5α-pregnan-20-one; 3α,5α-THP) is a positive modulator of the γ-aminobutyric acid type A…”
Get full text

Functional expression of an ovine growth hormone receptor in transfected Chinese hamster ovary cells by Fiddes, R J, Brandon, M R, Adams, T E

“…Structural heterogeneity has been demonstrated for growth hormone (GH) receptors from a number of species, and both high and low affinity art receptors have…”
Get more information

Analysis of Grb7 Recruitment by Heregulin-activated erbB Receptors Reveals a Novel Target Selectivity for erbB3 by Fiddes, R J, Campbell, D H, Janes, P W, Sivertsen, S P, Sasaki, H, Wallasch, C, Daly, R J

“…Heregulin-mediated activation of particular erbB receptor combinations was used as a model system to investigate the interaction of erbB3 and erbB4 with the…”
Get full text

The sheep growth hormone receptor: molecular cloning and ontogeny of mRNA expression in the liver by Adams, T E, Baker, L, Fiddes, R J, Brandon, M R

“…Two overlapping cDNA clones encoding the sheep growth hormone (GH) receptor were isolated from a sheep liver cDNA library. The translated amino acid sequence…”
Get more information

Granulosa Cell Tumors Express erbB4 and Are Sensitive to the Cytotoxic Action of Heregulin- beta 2/PE40 by Furger, C, Fiddes, R J, Quinn, DI, Bova, R J, Daly, R J, Sutherland, R L

“…The molecular genetic events involved in the etiology of human granulosa cell (GC) tumors, which represent similar to 7% of all malignant ovarian neoplasms,…”
Get full text

Heregulin (HRG)-induced mitogenic signaling and cytotoxic activity of a HRG/PE40 ligand toxin in human breast cancer cells by FIDDES, R. J, JANES, P. W, SANDERSON, G. M, SIVERTSEN, S. P, SUTHERLAND, R. L, DALY, R. J

“…The heregulins (HRGs) are a family of growth factors that bind direction to erbB3 and erbB4 and induce tyrosine phosphorylation of erbB2 via receptor…”
Get full text

Isolation of human anti-c- erb B-2 Fabs from a lymph node-derived phage display library by CLARK, M A, HAWKINS, N J, PAPAIOANNOU, A, FIDDES, R J, WARD, R L

“…An immunoglobulin phage display library constructed from a tumour-associated pericolic lymph node was panned against the extracellular domain of the…”
Get full text

Granulosa cell tumors express erbB4 and are sensitive to the cytotoxic action of heregulin-β2/PE40 by FURGER, C, FIDDES, R. J, QUINN, D. I, BOVA, R. J, DALY, R. J, SUTHERLAND, R. L

Get full text

Granulosa cell tumors express erbB4 and are sensitive to the cytotoxic action of heregulin-beta2/PE40 by Furger, C, Fiddes, R J, Quinn, D I, Bova, R J, Daly, R J, Sutherland, R L

“…The molecular genetic events involved in the etiology of human granulosa cell (GC) tumors, which represent approximately 7% of all malignant ovarian neoplasms,…”
Get full text

A key enzyme in the biosynthesis of neurosteroids, 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4-isomerase (3 beta-HSD), is expressed in rat brain by Guennoun, R, Fiddes, R J, Gouézou, M, Lombès, M, Baulieu, E E

“…In rat brain, the presence of pregnenolone and progesterone, not attributable to peripheral glandular sources, has been demonstrated and thus the two compounds…”
Get full text

A key enzyme in the biosynthesis of neurosteroids, 3 beta -hydroxysteroid dehydrogenase/ Delta super(5)- Delta super(4)-isomerase (3 beta -HSD), is expressed in rat brain by Guennoun, R, Fiddes, R J, Gouezou, M, Lombes, M, Baulieu, E-E

“…In rat brain, the presence of pregnenolone and progesterone, not attributable to peripheral glandular sources, has been demonstrated and thus the two compounds…”
Get full text

A key enzyme in the biosynthesis of neurosteroids, 3β-hydroxysteroid dehydrogenase/ Δ5- Δ4-isomerase (3β-HSD), is expressed in rat brain by Guennoun, R., Fiddes, R.J., Gouézou, M., Lombès, M., Baulieu, E-E.

“…In rat brain, the presence of pregnenolone and progesterone, not attributable to peripheral glandular sources, has been demonstrated and thus the two compounds…”
Get full text