Search Results - "FEUCHTINGER, ANNETTE"

Post-surgical adhesions are triggered by calcium-dependent membrane bridges between mesothelial surfaces by Fischer, Adrian, Koopmans, Tim, Ramesh, Pushkar, Christ, Simon, Strunz, Maximilian, Wannemacher, Juliane, Aichler, Michaela, Feuchtinger, Annette, Walch, Axel, Ansari, Meshal, Theis, Fabian J., Schorpp, Kenji, Hadian, Kamyar, Neumann, Philipp-Alexander, Schiller, Herbert B., Rinkevich, Yuval

“…Surgical adhesions are bands of scar tissues that abnormally conjoin organ surfaces. Adhesions are a major cause of post-operative and dialysis-related…”
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Liver-fibrosis-activated transcriptional networks govern hepatocyte reprogramming and intra-hepatic communication by Loft, Anne, Alfaro, Ana Jimena, Schmidt, Søren Fisker, Pedersen, Felix Boel, Terkelsen, Mike Krogh, Puglia, Michele, Chow, Kan Kau, Feuchtinger, Annette, Troullinaki, Maria, Maida, Adriano, Wolff, Gretchen, Sakurai, Minako, Berutti, Riccardo, Ekim Üstünel, Bilgen, Nawroth, Peter, Ravnskjaer, Kim, Diaz, Mauricio Berriel, Blagoev, Blagoy, Herzig, Stephan

“…Liver fibrosis is a strong predictor of long-term mortality in individuals with metabolic-associated fatty liver disease; yet, the mechanisms underlying the…”
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Mass Spectrometry Imaging Establishes 2 Distinct Metabolic Phenotypes of Aldosterone-Producing Cell Clusters in Primary Aldosteronism by Sun, Na, Meyer, Lucie S., Feuchtinger, Annette, Kunzke, Thomas, Knösel, Thomas, Reincke, Martin, Walch, Axel, Williams, Tracy Ann

“…Aldosterone-producing adenomas (APAs) are one of the main causes of primary aldosteronism and the most prevalent surgically correctable form of hypertension…”
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High-mass-resolution MALDI mass spectrometry imaging of metabolites from formalin-fixed paraffin-embedded tissue by Ly, Alice, Buck, Achim, Balluff, Benjamin, Sun, Na, Gorzolka, Karin, Feuchtinger, Annette, Janssen, Klaus-Peter, Kuppen, Peter J K, van de Velde, Cornelis J H, Weirich, Gregor, Erlmeier, Franziska, Langer, Rupert, Aubele, Michaela, Zitzelsberger, Horst, McDonnell, Liam, Aichler, Michaela, Walch, Axel

“…Formalin-fixed paraffin embedding (FFPE) of tissues has been assumed to alter the metabolite content or chemical state, hampering metabolomics studies. Here,…”
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Fluorescent blood–brain barrier tracing shows intact leptin transport in obese mice by Harrison, Luke, Schriever, Sonja C., Feuchtinger, Annette, Kyriakou, Eleni, Baumann, Peter, Pfuhlmann, Katrin, Messias, Ana C., Walch, Axel, Tschöp, Matthias H., Pfluger, Paul T.

“…Background/objectives Individuals carrying loss-of-function gene mutations for the adipocyte hormone leptin are morbidly obese, but respond favorably to…”
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Multimodal analysis of formalin-fixed and paraffin-embedded tissue by MALDI imaging and fluorescence in situ hybridization for combined genetic and metabolic analysis by Huber, Katharina, Kunzke, Thomas, Buck, Achim, Langer, Rupert, Luber, Birgit, Feuchtinger, Annette, Walch, Axel

“…Multimodal tissue analyses that combine two or more detection technologies provide synergistic value compared to single methods and are employed increasingly…”
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A practical guide to unbiased quantitative morphological analyses of the gills of rainbow trout (Oncorhynchus mykiss) in ecotoxicological studies by Fiedler, Sonja, Wünnemann, Hannah, Hofmann, Isabel, Theobalt, Natalie, Feuchtinger, Annette, Walch, Axel, Schwaiger, Julia, Wanke, Rüdiger, Blutke, Andreas

“…Rainbow trout (Oncorhynchus mykiss) are frequently used as experimental animals in ecotoxicological studies, in which they are experimentally exposed to…”
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In Situ Metabolomics of Cortisol-Producing Adenomas by Murakami, Masanori, Sun, Na, Li, Fengxia, Feuchtinger, Annette, Gomez-Sanchez, Celso, Fassnacht, Martin, Reincke, Martin, Bancos, Irina, Walch, Axel, Kroiss, Matthias, Beuschlein, Felix

“…Received June 8, 2022; accepted October 11, 2022 Background Recent advances in omics techniques have allowed detailed genetic characterization of…”
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The Intratumoral Heterogeneity Reflects the Intertumoral Subtypes of Glioblastoma Multiforme: A Regional Immunohistochemistry Analysis by Bergmann, Natalie, Delbridge, Claire, Gempt, Jens, Feuchtinger, Annette, Walch, Axel, Schirmer, Lucas, Bunk, Wolfram, Aschenbrenner, Thomas, Liesche-Starnecker, Friederike, Schlegel, Jürgen

“…Glioblastoma multiforme (GBM) is the most frequent and aggressive primary brain tumor in adults. Despite extensive therapy the prognosis for GBM patients…”
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A simple preparation step to remove excess liquid lipids in white adipose tissue enabling improved detection of metabolites via MALDI-FTICR imaging MS by Wang, Qian, Sun, Na, Kunzke, Thomas, Buck, Achim, Shen, Jian, Prade, Verena M., Stöckl, Barbara, Wang, Jun, Feuchtinger, Annette, Walch, Axel

“…Matrix-assisted laser desorption ionization (MALDI) Fourier transform ion cyclotron resonance (FTICR) imaging mass spectrometry (MS) is a powerful technology…”
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Light sheet fluorescence microscopy guided MALDI-imaging mass spectrometry of cleared tissue samples by Blutke, Andreas, Sun, Na, Xu, Zhihao, Buck, Achim, Harrison, Luke, Schriever, Sonja C., Pfluger, Paul T., Wiles, David, Kunzke, Thomas, Huber, Katharina, Schlegel, Jürgen, Aichler, Michaela, Feuchtinger, Annette, Matiasek, Kaspar, Hauck, Stefanie M., Walch, Axel

“…Light sheet fluorescence microscopy (LSFM) of optically cleared biological samples represents a powerful tool to analyze the 3-dimensional morphology of…”
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Deciphering Membrane-Associated Molecular Processes in Target Tissue of Autoimmune Uveitis by Label-Free Quantitative Mass Spectrometry by Hauck, Stefanie M., Dietter, Johannes, Kramer, Roxane L., Hofmaier, Florian, Zipplies, Johanna K., Amann, Barbara, Feuchtinger, Annette, Deeg, Cornelia A., Ueffing, Marius

“…Autoimmune uveitis is a blinding disease presenting with autoantibodies against eye-specific proteins as well as autoagressive T cells invading and attacking…”
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De novo discovery of metabolic heterogeneity with immunophenotype-guided imaging mass spectrometry by Prade, Verena M., Kunzke, Thomas, Feuchtinger, Annette, Rohm, Maria, Luber, Birgit, Lordick, Florian, Buck, Achim, Walch, Axel

“…Imaging mass spectrometry enables in situ label-free detection of thousands of metabolites from intact tissue samples. However, automated steps for multi-omics…”
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Stem cell-derived vessels-on-chip for cardiovascular disease modeling by Marder, Maren, Remmert, Caroline, Perschel, Julius A., Otgonbayar, Munkhtur, von Toerne, Christine, Hauck, Stefanie, Bushe, Judith, Feuchtinger, Annette, Sheikh, Bilal, Moussus, Michel, Meier, Matthias

“…The metabolic syndrome is accompanied by vascular complications. Human in vitro disease models are hence required to better understand vascular dysfunctions…”
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Mitochondrial Alkbh1 localizes to mtRNA granules and its knockdown induces the mitochondrial UPR in humans and C. elegans by Wagner, Anita, Hofmeister, Olga, Rolland, Stephane G, Maiser, Andreas, Aasumets, Koit, Schmitt, Sabine, Schorpp, Kenji, Feuchtinger, Annette, Hadian, Kamyar, Schneider, Sabine, Zischka, Hans, Leonhardt, Heinrich, Conradt, Barbara, Gerhold, Joachim M, Wolf, Alexander

“…The Fe(II) and 2-oxoglutarate-dependent oxygenase Alkb homologue 1 (Alkbh1) has been shown to act on a wide range of substrates, like DNA, tRNA and histones…”
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Steroid metabolome analysis reveals prevalent glucocorticoid excess in primary aldosteronism by Arlt, Wiebke, Lang, Katharina, Sitch, Alice J, Dietz, Anna S, Rhayem, Yara, Bancos, Irina, Feuchtinger, Annette, Chortis, Vasileios, Gilligan, Lorna C, Ludwig, Philippe, Riester, Anna, Asbach, Evelyn, Hughes, Beverly A, O'Neil, Donna M, Bidlingmaier, Martin, Tomlinson, Jeremy W, Hassan-Smith, Zaki K, Rees, D Aled, Adolf, Christian, Hahner, Stefanie, Quinkler, Marcus, Dekkers, Tanja, Deinum, Jaap, Biehl, Michael, Keevil, Brian G, Shackleton, Cedric Hl, Deeks, Jonathan J, Walch, Axel K, Beuschlein, Felix, Reincke, Martin

“…Adrenal aldosterone excess is the most common cause of secondary hypertension and is associated with increased cardiovascular morbidity. However, adverse…”
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Chronic Occupational Exposure to Ionizing Radiation Induces Alterations in the Structure and Metabolism of the Heart: A Proteomic Analysis of Human Formalin-Fixed Paraffin-Embedded (FFPE) Cardiac Tissue by Azimzadeh, Omid, Azizova, Tamara, Merl-Pham, Juliane, Blutke, Andreas, Moseeva, Maria, Zubkova, Olga, Anastasov, Natasa, Feuchtinger, Annette, Hauck, Stefanie M, Atkinson, Michael J, Tapio, Soile

“…Epidemiological studies on workers employed at the Mayak plutonium enrichment plant have demonstrated an association between external gamma ray exposure and an…”
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Dipeptide metabolite, glutamyl-glutamate mediates microbe-host interaction to boost spermatogenesis by Juhász, Balázs, Horváth, Krisztina, Kuti, Dániel, Shen, Jian, Feuchtinger, Annette, Zhang, Chaoyang, Bata-Vidács, Ildikó, Nagy, István, Kukolya, József, Witting, Michael, Baranyi, Mária, Ferenczi, Szilamér, Walch, Axel, Sun, Na, Kovács, Krisztina J.

“…The decrease in sperm count and infertility is a global issue that remains unresolved. By screening environmental bacterial isolates, we have found that a…”
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Coordinated targeting of cold and nicotinic receptors synergistically improves obesity and type 2 diabetes by Clemmensen, Christoffer, Jall, Sigrid, Kleinert, Maximilian, Quarta, Carmelo, Gruber, Tim, Reber, Josefine, Sachs, Stephan, Fischer, Katrin, Feuchtinger, Annette, Karlas, Angelos, Simonds, Stephanie E., Grandl, Gerald, Loher, Daniela, Sanchez-Quant, Eva, Keipert, Susanne, Jastroch, Martin, Hofmann, Susanna M., Nascimento, Emmani B. M., Schrauwen, Patrick, Ntziachristos, Vasilis, Cowley, Michael A., Finan, Brian, Müller, Timo D., Tschöp, Matthias H.

“…Pharmacological stimulation of brown adipose tissue (BAT) thermogenesis to increase energy expenditure is progressively being pursued as a viable anti-obesity…”
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Correction: GIP receptor agonism improves dyslipidemia and atherosclerosis independently of body weight loss in preclinical mouse model for cardio-metabolic disease by Sachs, Stephan, Götz, Anna, Finan, Brian, Feuchtinger, Annette, DiMarchi, Richard D, Döring, Yvonne, Weber, Christian, Tschöp, Matthias H, Müller, Timo D, Hofmann, Susanna M

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