Search Results - "FERRIS, Steven H"

Age-related non-Gaussian diffusion patterns in the prefrontal brain by Falangola, Maria F., Jensen, Jens H., Babb, James S., Hu, Caixia, Castellanos, Francisco X., Di Martino, Adriana, Ferris, Steven H., Helpern, Joseph A.

“…Purpose To characterize age‐related MR diffusion patterns of the prefrontal brain cortex microstructure using a new method for investigating the non‐Gaussian…”
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White matter tract integrity metrics reflect the vulnerability of late-myelinating tracts in Alzheimer's disease by Benitez, Andreana, Fieremans, Els, Jensen, Jens H, Falangola, Maria F, Tabesh, Ali, Ferris, Steven H, Helpern, Joseph A

“…Post-mortem and imaging studies have observed that white matter (WM) degenerates in a pattern inverse to myelin development, suggesting preferential regional…”
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Mild cognitive impairment (MCI): a historical perspective by Reisberg, Barry, Ferris, Steven H, Kluger, Alan, Franssen, Emile, Wegiel, Jerzy, de Leon, Mony J

“…Descriptions of dementia can be traced to antiquity. Prichard (1837) described four dementia stages and Kral (1962) described a "benign senescent…”
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Tracking early decline in cognitive function in older individuals at risk for Alzheimer disease dementia: the Alzheimer's Disease Cooperative Study Cognitive Function Instrument by Amariglio, Rebecca E, Donohue, Michael C, Marshall, Gad A, Rentz, Dorene M, Salmon, David P, Ferris, Steven H, Karantzoulis, Stella, Aisen, Paul S, Sperling, Reisa A

“…Several large-scale Alzheimer disease (AD) secondary prevention trials have begun to target individuals at the preclinical stage. The success of these trials…”
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Language impairment in Alzheimer's disease and benefits of acetylcholinesterase inhibitors by Ferris, Steven H, Farlow, Martin

“…Alzheimer's disease is characterized by progressively worsening deficits in several cognitive domains, including language. Language impairment in Alzheimer's…”
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Clinical efficacy of piracetam in cognitive impairment: a meta-analysis by Waegemans, Tony, Wilsher, Colin R, Danniau, Anne, Ferris, Steven H, Kurz, Alexander, Winblad, Bengt

“…A meta-analysis has been performed including nineteen double blind, placebo controlled studies with piracetam in patients suffering from dementia or cognitive…”
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Neuropsychological prediction of decline to dementia in nondemented elderly by Kluger, A, Ferris, S H, Golomb, J, Mittelman, M S, Reisberg, B

“…This study examined whether baseline neuropsychological performance in elderly assessed at a research clinic could accurately predict subsequent decline to…”
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ADCS prevention instrument project : ADCS-clinicians' global impression of change scales (ADCS-CGIC), self-rated and study partner-rated versions by SCHNEIDER, Lon S, CLARK, Christopher M, DOODY, Rachelle, FERRIS, Steven H, MORRIS, John C, RAMAN, Rema, REISBERG, Barry, SCHMITT, Frederick A

“…Because primary prevention trials will require large samples and modest treatment effects are expected, the use of standard clinician-administered,…”
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Tramiprosate in mild-to-moderate Alzheimer's disease - a randomized, double-blind, placebo-controlled, multi-centre study (the Alphase Study) by Aisen, Paul S, Gauthier, Serge, Ferris, Steven H, Saumier, Daniel, Haine, Denis, Garceau, Denis, Duong, Anh, Suhy, Joyce, Oh, Joonmi, Lau, Wan C, Sampalis, John

“…The aim of the study was to assess the clinical efficacy, safety, and disease-modification effects of tramiprosate (homotaurine, ALZHEMED(TM)) in…”
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Health-Related Resource Use and Costs in Elderly Adults with and without Mild Cognitive Impairment by Zhu, Carolyn W., Sano, Mary, Ferris, Steven H., Whitehouse, Peter J., Patterson, Marian B., Aisen, Paul S.

“…Objectives To assess differences in resource use and cost between older adults with and without mild cognitive impairment (MCI) over time. Design Multicenter,…”
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A Randomized, Double-Blind, Study of Rofecoxib in Patients with Mild Cognitive Impairment by THAL, Leon J, FERRIS, Steven H, REINES, Scott A, KIRBY, Louis, BLOCK, Gilbert A, LINES, Christopher R, YUEN, Eric, ASSAID, Christopher, NESSLY, Michael L, NORMAN, Barbara A, BARANAK, Christine C

“…Inflammatory mechanisms have been implicated in Alzheimer's disease (AD) and might be mediated via the COX-2 enzyme. Previous studies with the selective COX-2…”
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Effects of N-PEP-12 on memory among older adults by Crook, Thomas H, Ferris, Steven H, Alvarez, X Anton, Laredo, Martha, Moessler, Herbert

“…N-PEP-12 is a derivative of cerebrolysin, a brain-derived neuropeptide compound that has been approved for the treatment of Alzheimerʼs disease (AD) in more…”
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Age and Apolipoprotein E Genotype Influence Rate of Cognitive Decline in Nondemented Elderly by Salmon, David P, Ferris, Steven H, Thomas, Ronald G, Sano, Mary, Cummings, Jeffery L, Sperling, Reisa A, Petersen, Ronald C, Aisen, Paul S

“…Objective: This study examined the impact of age and apolipoprotein E (APOE) genotype on the rate of cognitive decline in nondemented elderly participants in a…”
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Evaluation of memantine for the treatment of Alzheimer's disease by Ferris, Steven H

“…Increasing evidence suggests that disturbances in glutamatergic activity play an important role in Alzheimer's disease (AD). Excessive glutamate-mediated…”
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Alzheimer's Disease Cooperative Study Prevention Instrument Project Assessing Resource Use and Volunteer and Paid Work in Healthy Elders: A Longitudinal Study by Zhu, Carolyn W., Sano, Mary, Ferris, Steven H., Whitehouse, Peter J., Patterson, Marian B., Galasko, Douglas, Schneider, Lon S., Aisen, Paul S.

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ADCS prevention instrument project : Development of a brief verbal memory test for primary prevention clinical trials by SALMON, David P, CUMMINGS, Jeffrey L, JIN, Shelia, SANO, Mary, SPERLING, Reisa A, ZAMRINI, Edward, PETERSEN, Ronald C, EDLAND, Steven D, THAI, Leon J, FERRIS, Steven H

“…The validity and reliability of clinic-based and telephone-based versions of a 4 word delayed recall test were evaluated in nondemented elderly individuals…”
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General measures of cognition by Ferris, Steven H

“…A general cognitive performance battery is needed as a primary outcome in vascular dementia clinical trials. Because there is considerable overlap between…”
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Synergistic effect of apolipoprotein E ε4 and butyrylcholinesterase K-variant on progression from mild cognitive impairment to Alzheimer's disease by LANE, Roger, FELDMAN, Howard H, SFIKAS, Nikolaos, BALLARD, Clive, GREIG, Nigel H, MEYER, Joanne, YUNSHENG HE, FERRIS, Steven H, NORDBERG, Agneta, DARREH-SHORI, Taher, SOININEN, Hilkka, PIRTTILÄ, Tuula, FARLOW, Martin R

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Analyzing the impact of 23 mg/day donepezil on language dysfunction in moderate to severe Alzheimer's disease by Ferris, Steven H, Schmitt, Frederick A, Saxton, Judith, Richardson, Sharon, Mackell, Joan, Sun, Yijun, Xu, Yikang

“…Progressive language impairment is among the primary components of cognitive decline in Alzheimer's disease (AD). Because expressive and receptive language…”
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Effects of rivastigmine transdermal patch and capsule on aspects of clinical global impression of change in Alzheimer's disease: a retrospective analysis by Cummings, Jeffrey L, Ferris, Steven H, Farlow, Martin R, Olin, Jason T, Meng, Xiangyi

“…The Alzheimer's Disease Cooperative Study-Clinical Global Impression of Change (ADCS-CGIC) scale is widely used in Alzheimer trials. It assesses cognition,…”
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