Search Results - "FERRERA, René"

Mesenchymal stem cells sense mitochondria released from damaged cells as danger signals to activate their rescue properties by Mahrouf-Yorgov, Meriem, Augeul, Lionel, Da Silva, Claire Crola, Jourdan, Maud, Rigolet, Muriel, Manin, Sylvie, Ferrera, René, Ovize, Michel, Henry, Adeline, Guguin, Aurélie, Meningaud, Jean-Paul, Dubois-Randé, Jean-Luc, Motterlini, Roberto, Foresti, Roberta, Rodriguez, Anne-Marie

“…Mesenchymal stem cells (MSCs) protect tissues against cell death induced by ischemia/reperfusion insults. This therapeutic effect seems to be controlled by…”
Get full text

Postconditioning by Delayed Administration of Ciclosporin A: Implication for Donation after Circulatory Death (DCD) by Ferrera, René, Védère, Marie, Lo-Grasso, Megane, Augeul, Lionel, Chouabe, Christophe, Bidaux, Gabriel, Baetz, Delphine

“…Heart transplantation is facing a shortage of grafts. Donation after Circulatory Death (DCD) would constitute a new potential of available organs. In the…”
Get full text

Mesenchymal stem cell conditioned media attenuates in vitro and ex vivo myocardial reperfusion injury by Angoulvant, Denis, MD, PhD, Ivanes, Fabrice, MD, MSc, Ferrera, René, PhD, Matthews, Phoebe G., BSc, Nataf, Serge, MD, PhD, Ovize, Michel, MD, PhD

“…Background Previous studies have suggested that implantation of mesenchymal stem cells (MSC) or their conditioned media (MSC CM) improves heart function after…”
Get full text

Quantitative stiffness assessment of cardiac grafts using ultrasound in a porcine model: A tissue biomarker for heart transplantation by Pedreira, Olivier, Papadacci, Clement, Augeul, Lionel, Loufouat, Joseph, Lo-Grasso, Mégane, Tanter, Mickael, Ferrera, René, Pernot, Mathieu

“…Heart transplantation is the definitive treatment for many cardiovascular diseases. However, no ideal approach is established to evaluate heart grafts and it…”
Get full text

Isolated Mitochondria State after Myocardial Ischemia-Reperfusion Injury and Cardioprotection: Analysis by Flow Cytometry by Crola Da Silva, Claire, Baetz, Delphine, Védère, Marie, Lo-Grasso, Mégane, Wehbi, Mariam, Chouabe, Christophe, Bidaux, Gabriel, Ferrera, René

“…Mitochondria are key organelles involved in cell survival and death during the acute phenomena of myocardial ischemia-reperfusion (i.e., myocardial…”
Get full text

Cardiac fibroblasts protect cardiomyocytes against lethal ischemia–reperfusion injury by Abrial, Maryline, Da Silva, Claire Crola, Pillot, Bruno, Augeul, Lionel, Ivanes, Fabrice, Teixeira, Geoffrey, Cartier, Régine, Angoulvant, Denis, Ovize, Michel, Ferrera, René

“…Abstract Roles of cardiac fibroblasts (CFs) in the regulation of myocardial structure and function have been emphasized in the last decade. Their implications…”
Get full text

In vitro and in vivo models of cerebral ischemia show discrepancy in therapeutic effects of M2 macrophages by Desestret, Virginie, Riou, Adrien, Chauveau, Fabien, Cho, Tae-Hee, Devillard, Emilie, Marinescu, Marilena, Ferrera, René, Rey, Catherine, Chanal, Marie, Angoulvant, Denis, Honnorat, Jérôme, Nighoghossian, Norbert, Berthezène, Yves, Nataf, Serge, Wiart, Marlène

“…THE INFLAMMATORY RESPONSE FOLLOWING ISCHEMIC STROKE IS DOMINATED BY INNATE IMMUNE CELLS: resident microglia and blood-derived macrophages. The ambivalent role…”
Get full text

Unacylated ghrelin analog prevents myocardial reperfusion injury independently of permeability transition pore by Harisseh, Rania, Pillot, Bruno, Gharib, Abdallah, Augeul, Lionel, Gallo-Bona, Noelle, Ferrera, René, Loufouat, Joseph, Delale, Thomas, Allas, Soraya, Abribat, Thierry, Crola Da Silva, Claire, Ovize, Michel

“…Reperfusion injury is responsible for an important part of myocardial infarct establishment due notably to triggering cardiomyocytes death at the first minutes…”
Get full text

Assessment of coronary microcirculation alterations in a porcine model of no-reflow using ultrasound localization microscopy: a proof of concept study by Demeulenaere, Oscar, Mateo, Philippe, Ferrera, René, Chiaroni, Paul-Mathieu, Bizé, Alain, Dai, Jianping, Sambin, Lucien, Gallet, Romain, Tanter, Mickaël, Papadacci, Clément, Ghaleh, Bijan, Pernot, Mathieu

“…Coronary microvascular obstruction also known as no-reflow phenomenon is a major issue during myocardial infarction that bears important prognostic…”
Get full text

Delayed low pressure at reperfusion: A new approach for cardioprotection by Ferrera, René, PhD, Benhabbouche, Souhila, PhD, Da Silva, Claire Crola, PhD, Alam, Muhammad Rizwan, PhD, Ovize, Michel, MD, PhD

“…Abstract Objectives The aims of this study were to evaluate whether the delayed application of low-pressure reperfusion could reduce lethal reperfusion injury…”
Get full text

Cooling Uncouples Differentially ROS Production from Respiration and Ca2+ Homeostasis Dynamic in Brain and Heart Mitochondria by Stevic, Neven, Maalouf, Jennifer, Argaud, Laurent, Gallo-Bona, Noëlle, Lo Grasso, Mégane, Gouriou, Yves, Gomez, Ludovic, Crola Da Silva, Claire, Ferrera, René, Ovize, Michel, Cour, Martin, Bidaux, Gabriel

“…Hypothermia provides an effective neuro and cardio-protection in clinical settings implying ischemia/reperfusion injury (I/R). At the onset of reperfusion,…”
Get full text

Volatile anaesthetics and cardioprotection - lessons from animal studies by Muntean, Danina M., Ordodi, Valentin, Ferrera, René, Angoulvant, Denis

“…Volatile anaesthetics emerged as important cardioprotective agents in both animal models of ischaemia/reperfusion injury and humans with coronary artery…”
Get full text

Determination of the myocardial area at risk with pre- versus post-reperfusion imaging techniques in the pig model by Mewton, Nathan, Rapacchi, Stanislas, Augeul, Lionel, Ferrera, René, Loufouat, Joseph, Boussel, Loic, Micolich, Alejandra, Rioufol, Gilles, Revel, Didier, Ovize, Michel, Croisille, Pierre

“…The purpose of this study was to compare the accuracy of post-reperfusion cardiac magnetic resonance (CMR) and pre-reperfusion multidetector computed…”
Get full text

Improving donor heart preservation ex vivo by Ferrera, René, Benhabbouche, Souhila

“…There is a shortage of heart donors. Some available organs are lost through deterioration prior to transplantation. Indeed, from the moment of brain death…”
Get more information

Post-conditioning Protects From Cardioplegia and Cold Ischemia via Inhibition of Mitochondrial Permeability Transition Pore by Ferrera, René, PhD, Bopassa, Jean-Chrisostome, PhD, Angoulvant, Denis, MD, PhD, Ovize, Michel, MD, PhD

“…Background The aim of this study was to evaluate the role of the mitochondrial permeability transition pore (MPTP) in the protection achieved by…”
Get full text

Brain death provokes very acute alteration in myocardial morphology detected by echocardiography: preventive effect of beta-blockers by Ferrera, René, Hadour, Guylaine, Tamion, Fabienne, Henry, Jean-Paul, Mulder, Paul, Richard, Vincent, Thuillez, Christian, Ovize, Michel, Derumeaux, Geneviève

“…Our objective was to evaluate immediate acute changes in myocardial function during the autonomic storm of brain death (BD). Wistar rats were divided into four…”
Get more information

Determination of the myocardial area at risk after reperfused acute myocardial infarction with different imaging techniques: cardiac magnetic resonance imaging, multidetector computed tomography and histopathological validation by Mewton, Nathan, Rapacchi, Stanislas, Augeul, Lionel, Ferrera, René, Loufouat, Joseph, Boussel, Loic, Rioufol, Gilles, Revel, Didier, Ovize, Michel, Croisille, Pierre

“…n.a…”
Get full text

Brain death does not change epicardial action potentials and their response to ischemia-reperfusion in open-chest pigs by Christé, Georges, Hadour, Guylaine, Ovize, Michel, Ferrera, René

“…It is debated whether brain death (BD) causes transient functional ischemia. In this investigation we used monophasic action potential (AP) recording during BD…”
Get more information

Characterization of antiproliferative and cytotoxic properties of the HSV-1 immediate-early ICP0 protein by Cuchet, Delphine, Ferrera, René, Lomonte, Patrick, Epstein, Alberto L.

“…Background The identification of novel proteins displaying cytostatic and/or cytotoxic actions that could eventually be used for gene therapy is a major issue…”
Get full text

Preservation of ischemia and isoflurane-induced preconditioning after brain death in rabbit hearts by Chiari, Pascal, Piriou, Vincent, Hadour, Guylaine, Rodriguez, Claire, Loufouat, Joseph, Lehot, Jean-Jacques, Ovize, Michel, Ferrera, René

“…We sought to determine whether brain death-induced catecholamine release preconditions the heart, and if not, whether it precludes further protection by…”
Get more information