Search Results - "FERREIRA, Elizabeth Igne"
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New Advances in General Biomedical Applications of PAMAM Dendrimers
Published in Molecules (Basel, Switzerland) (02-11-2018)“…Dendrimers are nanoscopic compounds, which are monodispersed, and they are generally considered as homogeneous. PAMAM (polyamidoamine) was introduced in 1985,…”
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Dendrimer Prodrugs
Published in Molecules (Basel, Switzerland) (31-05-2016)“…The main objective of this review is to describe the importance of dendrimer prodrugs in the design of new drugs, presenting numerous applications of these…”
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Dendrimers in the context of nanomedicine
Published in International journal of pharmaceutics (05-01-2020)“…[Display omitted] Dendrimers are globular structures, presenting an initiator core, repetitive layers starting radially from the core and terminal groups on…”
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Targeting Groups Employed in Selective Dendrons and Dendrimers
Published in Pharmaceutics (08-11-2018)“…The design of compounds with directed action to a defined organ or tissue is a very promising approach, since it can decrease considerably the toxicity of the…”
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An Insight into the Discovery of Potent Antifilarial Leads Against Lymphatic Filariasis
Published in Current drug targets (01-01-2020)“…Lymphatic filariasis is a neglected tropical disease caused by infection with filarial worms that are transmitted through mosquito bites. Globally, 120 million…”
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Multi-walled carbon nanotube functionalization and the dispersing agents study applied for the glassy carbon electrode modification and voltammetric reduction of nitrofurazone
Published in Journal of solid state electrochemistry (01-08-2020)“…Multi-walled carbon nanotubes (MWCNTs) have structures characterized by remarkable mechanical and electronic properties. However, their applications can be…”
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Discovery of Novel Inhibitors of Cruzain Cysteine Protease of Trypanosoma cruzi
Published in Current medicinal chemistry (01-01-2024)“…Chagas disease (CD) is a parasitic disease endemic in several developing countries. According to the World Health Organization, approximately 6-8 million…”
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Covalent Inhibitors for Neglected Diseases: An Exploration of Novel Therapeutic Options
Published in Pharmaceuticals (Basel, Switzerland) (01-07-2023)“…Neglected diseases, primarily found in tropical regions of the world, present a significant challenge for impoverished populations. Currently, there are 20…”
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The Importance of the Piperazine Ring for the Development of Trypanomicide Compounds
Published in ChemistrySelect (Weinheim) (05-09-2023)“…Chagas disease (CD) is one of extremely Neglected Tropical Diseases (NTD) that have been challenging the health of billions of people in the world. Despite…”
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Image-Based In Vitro Screening Reveals the Trypanostatic Activity of Hydroxymethylnitrofurazone against Trypanosoma cruzi
Published in International journal of molecular sciences (01-07-2021)“…Hydroxymethylnitrofurazone (NFOH) is a therapeutic candidate for Chagas disease (CD). It has negligible hepatotoxicity in a murine model compared to the…”
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Malaria and tuberculosis as diseases of neglected populations: state of the art in chemotherapy and advances in the search for new drugs
Published in Memórias do Instituto Oswaldo Cruz (01-01-2020)“…Malaria and tuberculosis are no longer considered to be neglected diseases by the World Health Organization. However, both are huge challenges and public…”
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Drug design for neglected disease in Brazil
Published in Mini reviews in medicinal chemistry (01-01-2015)“…Neglected tropical diseases (NTD) are a group of 17 diseases transmitted by virus, protozoa, helminthes and bacteria. These illnesses are responsible for…”
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Resveratrol and Curcumin for Chagas Disease Treatment-A Systematic Review
Published in Pharmaceuticals (Basel, Switzerland) (15-05-2022)“…Chagas disease (CD) is a neglected protozoan infection caused by , which affects about 7 million people worldwide. There are two available drugs in…”
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Twenty years of LASSBio, the laboratory of evaluation and synthesis of bioactive substances
Published in Brazilian Journal of Pharmaceutical Sciences (01-09-2014)Get full text
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Chemometric studies on natural products as potential inhibitors of the NADH oxidase from Trypanosoma cruzi using the VolSurf approach
Published in Molecules (Basel, Switzerland) (21-10-2010)“…Natural products have widespread biological activities, including inhibition of mitochondrial enzyme systems. Some of these activities, for example…”
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Internationalizing Brazilian Pharmaceutical Sciences
Published in Brazilian Journal of Pharmaceutical Sciences (01-09-2013)Get full text
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Pharmacists and their new and important conquest
Published in Brazilian Journal of Pharmaceutical Sciences (01-12-2014)Get full text
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BJPS as strategical for Pharmaceutical Sciences
Published in Brazilian Journal of Pharmaceutical Sciences (01-03-2012)Get full text
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Prodrugs for the treatment of neglected diseases
Published in Molecules (Basel, Switzerland) (01-03-2008)“…Recently, World Health Organization (WHO) and Medicins San Frontieres (MSF) proposed a classification of diseases as global, neglected and extremely neglected…”
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Pharmacokinetics of Hydroxymethylnitrofurazone, a Promising New Prodrug for Chagas' Disease Treatment
Published in Antimicrobial Agents and Chemotherapy (01-12-2013)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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