Search Results - "FERRACIN, Manuela"
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Overexpression of ultraconserved region 83- induces lung cancer tumorigenesis
Published in PloS one (11-01-2022)“…The expression of non-coding RNAs (ncRNAs) is dysregulated in human cancers. The transcribed ultraconserved regions (T-UCRs) express long ncRNAs involved in…”
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2
P2X7 promotes metastatic spreading and triggers release of miRNA-containing exosomes and microvesicles from melanoma cells
Published in Cell death & disease (16-11-2021)“…Tumor growth and metastatic spreading are heavily affected by the P2X7 receptor as well as microvesicles and exosomes release into the tumor microenvironment…”
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3
Basal Cell Carcinoma: A Comprehensive Review
Published in International journal of molecular sciences (04-08-2020)“…Basal cell carcinoma (BCC) is the most common type of carcinoma worldwide. BCC development is the result of a complex interaction between environmental,…”
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4
Epigenetic and epitranscriptomic changes in colorectal cancer: Diagnostic, prognostic, and treatment implications
Published in Cancer letters (10-04-2018)“…A cancer cell is the final product of a complex mixture of genetic, epigenetic and epitranscriptomic alterations, whose final interplay contribute to cancer…”
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5
Targeting p53 and histone methyltransferases restores exhausted CD8+ T cells in HCV infection
Published in Nature communications (30-01-2020)“…Hepatitis C virus infection (HCV) represents a unique model to characterize, from early to late stages of infection, the T cell differentiation process leading…”
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6
Interplay between small and long non‐coding RNAs in cutaneous melanoma: a complex jigsaw puzzle with missing pieces
Published in Molecular oncology (01-01-2019)“…The incidence of cutaneous melanoma (CM) has increased in the past few decades. The biology of melanoma is characterized by a complex interaction between…”
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7
Combining Anti-Mir-155 with Chemotherapy for the Treatment of Lung Cancers
Published in Clinical cancer research (01-06-2017)“…The oncogenic miR-155 is upregulated in many human cancers, and its expression is increased in more aggressive and therapy-resistant tumors, but the molecular…”
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Circulating microRNAs, miR-939, miR-595, miR-519d and miR-494, Identify Cirrhotic Patients with HCC
Published in PloS one (28-10-2015)“…The performance of circulating biomarkers for the diagnosis of hepatocellular carcinoma (HCC) is sub-optimal. In this study we tested circulating microRNAs as…”
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MiR-122/Cyclin G1 Interaction Modulates p53 Activity and Affects Doxorubicin Sensitivity of Human Hepatocarcinoma Cells
Published in Cancer research (Chicago, Ill.) (15-07-2009)“…The identification of target genes is a key step for assessing the role of aberrantly expressed microRNAs (miRNA) in human cancer and for the further…”
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10
Long-term exposure of human endothelial cells to metformin modulates miRNAs and isomiRs
Published in Scientific reports (11-12-2020)“…Increasing evidence suggest that the glucose-lowering drug metformin exerts a valuable anti-senescence role. The ability of metformin to affect the biogenesis…”
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11
Circulating Non-coding RNA as Biomarkers in Colorectal Cancer
Published in Advances in experimental medicine and biology (2016)“…Recent studies suggested that colorectal cancer influences the types and quantity of nucleic acids - especially microRNAs - detected in the bloodstream…”
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12
Resveratrol decreases the levels of miR-155 by upregulating miR-663, a microRNA targeting JunB and JunD
Published in Carcinogenesis (New York) (01-09-2010)“…An inflammatory component is present in the microenvironment of most neoplastic tissues, including those not causally related to an obvious inflammatory…”
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13
ARID1A in cancer: Friend or foe?
Published in Frontiers in oncology (20-02-2023)“…ARID1A belongs to a class of chromatin regulatory proteins that function by maintaining accessibility at most promoters and enhancers, thereby regulating gene…”
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14
A MicroRNA Signature of Hypoxia
Published in Molecular and Cellular Biology (01-03-2007)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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MicroRNA-221 Targets Bmf in Hepatocellular Carcinoma and Correlates with Tumor Multifocality
Published in Clinical cancer research (15-08-2009)“…Deregulated cell proliferation and apoptosis play a major role in hepatocellular carcinoma (HCC). MicroRNAs participate in the modulation of key molecules…”
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Cyclin G1 is a target of miR-122a, a microRNA frequently down-regulated in human hepatocellular carcinoma
Published in Cancer research (Chicago, Ill.) (01-07-2007)“…We investigated the role of microRNAs (miRNAs) in the pathogenesis of human hepatocellular carcinoma (HCC). A genome-wide miRNA microarray was used to identify…”
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17
Genomic stability, anti-inflammatory phenotype, and up-regulation of the RNAseH2 in cells from centenarians
Published in Cell death and differentiation (01-09-2019)“…Current literature agrees on the notion that efficient DNA repair favors longevity across evolution. The DNA damage response machinery activates inflammation…”
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18
MicroRNAs in human cancer: from research to therapy
Published in Journal of cell science (01-06-2007)“…Numerous miRNAs are deregulated in human cancers, and experimental evidence indicates that they can play roles as oncogenes or tumor suppressor genes…”
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Unraveling the role of microRNA/isomiR network in multiple primary melanoma pathogenesis
Published in Cell death & disease (12-05-2021)“…Malignant cutaneous melanoma (CM) is a potentially lethal form of skin cancer whose worldwide incidence has been constantly increasing over the past decades…”
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20
Micro-RNA profiling in kidney and bladder cancers
Published in Urologic oncology (01-09-2007)“…Abstract Objectives Micro-RNAs are a group of small noncoding RNAs with modulator activity of gene expression. Recently, micro-RNA genes were found abnormally…”
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