Search Results - "FERGUSON, M. A. J"

The structure, biosynthesis and function of glycosylated phosphatidylinositols in the parasitic protozoa and higher eukaryotes by MCCONVILLE, M. J, FERGUSON, M. A. J

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Structure of the CAMPATH-1 antigen, a glycosylphosphatidylinositol-anchored glycoprotein which is an exceptionally good target for complement lysis by MENG-QI XIA, HALE, G, LIFELY, M. R, FERGUSON, M. A. J, CAMPBELL, D, PACKMAN, L, WALDMANN, H

“…CAMPATH-1 antibodies recognize a unique molecule on human lymphocytes and are unusually efficient at causing cell lysis with homologous complement. They have…”
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Application of electrospray mass spectrometry to the structural determination of glycosylphosphatidylinositol membrane anchors by Nett, Isabelle R.E, Mehlert, Angela, Lamont, Douglas, Ferguson, Michael A.J

“…The addition of glycosylphosphatidylinositol (GPI) anchors to proteins is an important posttranslational modification in eukaryotic cells. The complete…”
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Cell-Surface Anchoring of Proteins Via Glycosyl-Phosphatidylinositol Structures by Ferguson, M A J, Williams, A F

“…A class of membrane molecules has been identified whose primary translation product includes a COOH-terminal protein sequence that signals attachment of a…”
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Characterization of glycoinositol phospholipids in the amastigote stage of the protozoan parasite Leishmania major by SCHNEIDER, P, ROSAT, J.-P, FERGUSON, M. A. J, MCCONVILLE, M. J

“…The major macromolecules on the surface of the parasitic protozoan Leishmania major appear to be down-regulated during transformation of the parasite from an…”
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Solution structure of the glycosylphosphatidylinositol membrane anchor glycan of Trypanosoma brucei variant surface glycoprotein by Homans, S. W, Edge, C. J, Ferguson, M. A. J, Dwek, R. A, Rademacher, T. W

“…The average solution conformation of the glycosylphosphatidylinositol (GPI) membrane anchor of Trypanosoma brucei variant surface glycoprotein (VSG) has been…”
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TrypanoCyc: a community-led biochemical pathways database for Trypanosoma brucei by Shameer, Sanu, Logan-Klumpler, Flora J, Vinson, Florence, Cottret, Ludovic, Merlet, Benjamin, Achcar, Fiona, Boshart, Michael, Berriman, Matthew, Breitling, Rainer, Bringaud, Frédéric, Bütikofer, Peter, Cattanach, Amy M, Bannerman-Chukualim, Bridget, Creek, Darren J, Crouch, Kathryn, de Koning, Harry P, Denise, Hubert, Ebikeme, Charles, Fairlamb, Alan H, Ferguson, Michael A J, Ginger, Michael L, Hertz-Fowler, Christiane, Kerkhoven, Eduard J, Mäser, Pascal, Michels, Paul A M, Nayak, Archana, Nes, David W, Nolan, Derek P, Olsen, Christian, Silva-Franco, Fatima, Smith, Terry K, Taylor, Martin C, Tielens, Aloysius G M, Urbaniak, Michael D, van Hellemond, Jaap J, Vincent, Isabel M, Wilkinson, Shane R, Wyllie, Susan, Opperdoes, Fred R, Barrett, Michael P, Jourdan, Fabien

“…The metabolic network of a cell represents the catabolic and anabolic reactions that interconvert small molecules (metabolites) through the activity of…”
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Glycosyl-phosphatidylinositol molecules of the parasite and the host by Ferguson, M A, Brimacombe, J S, Cottaz, S, Field, R A, Güther, L S, Homans, S W, McConville, M J, Mehlert, A, Milne, K G, Ralton, J E

“…The glycosyl-phosphatidylinositol (GPI) protein-membrane anchors are ubiquitous among the eukaryotes. However, while mammalian cells typically express in the…”
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Structure of the glycosyl-phosphatidylinositol membrane anchor of acetylcholinesterase from the electric organ of the electric-fish, Torpedo californica by MEHLERT, A, VARON, L, SILMAN, I, HOMANS, S. W, FERGUSON, M. A. J

“…The structure of the glycan moiety of the glycosyl-phosphatidylinositol (GPI) membrane anchor from Torpedo californica (electric fish) electric-organ…”
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Roles for glycosylation in the anti-inflammatory molecule CD59 by Rudd, P M, Morgan, B P, Wormald, M R, Harvey, D J, van den Berg, C W, Davis, S J, Ferguson, M A, Dwek, R A

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Structural characterization of a novel glycosyl-phosphatidylinositol from the protozoan Tetrahymena mimbres by WEINHART, U, THOMAS, J. R, PAK, Y, THOMPSON, G. A, FERGUSON, M. A. J

“…A glycolipid metabolically labelled with [14C]GlcN was isolated from the free-living protozoan Tetrahymena mimbres. The glycolipid was sensitive to a bacterial…”
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The N-glycan glucosidase system in Trypanosoma brucei by Jones, D, Mehlert, A, Ferguson, M A J

“…Reactions involving removal and addition of glucose to N-glycans in the ER (endoplasmic reticulum) are performed in higher eukaryotes by glucosidases I and II…”
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Developmental modification of lipophosphoglycan during the differentiation of Leishmania major promastigotes to an infectious stage by McConville, M.J., Turco, S.J., Ferguson, M.A., Sacks, D.L.

“…Protozoan parasites of the genus Leishmania produce the novel surface glycoconjugate, lipophosphoglycan (LPG), which is required for parasite infectivity. In…”
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Mucin-like glycoproteins linked to the membrane by glycosylphosphatidylinositol anchor are the major acceptors of sialic acid in a reaction catalyzed by trans-sialidase in metacyclic forms of Trypanosoma cruzi by Schenkman, S, Ferguson, M A, Heise, N, de Almeida, M L, Mortara, R A, Yoshida, N

“…We have previously shown that 35- and 50-kDa glycoconjugates of cultured metacyclic trypomastigotes participate in the attachment of parasites to mammalian…”
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Glycosyl-phosphatidylinositol moiety that anchors Trypanosoma brucei variant surface glycoprotein to the membrane by Ferguson, M.A.J, Homans, S.W, Dwek, R.A, Rademacher, T.W

“…Two forms of protein-membrane anchor have been described for the externally disposed glycoproteins of eukaryotic plasma membranes; namely, the hydrophobic…”
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Differential inhibitory mechanism of cyclic AMP on TNF‐α and IL‐12 synthesis by macrophages exposed to microbial stimuli by Procópio, Daniela O, Teixeira, Mauro M, Camargo, Maristela M, Travassos, Luiz R, Ferguson, Michael A J, Almeida, Igor C, Gazzinelli, Ricardo T

“…Microbial stimuli such as bacterial lipopolysaccharide (LPS) or glycosylphosphatidylinositol‐mucins derived from Trypanosoma cruzi trypomastigotes…”
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Site of palmitoylation of a phospholipase C-resistant glycosyl-phosphatidylinositol membrane anchor by FERGUSON, M. A. J

“…The site of palmitoylation of the phosphatidylinositol moiety of the glycosyl-phosphatidylinositol membrane anchor of Trypanosoma brucei procyclic repetitive…”
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Structure of the lipophosphoglycan from Leishmania major by McConville, M J, Thomas-Oates, J E, Ferguson, M A, Homans, S W

“…The major cell surface glycoconjugate of the parasitic protozoan Leishmania major is a heterogeneous lipophosphoglycan. It has a tripartite structure,…”
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Complete structure of the glycosyl phosphatidylinositol membrane anchor of rat brain Thy-1 glycoprotein by Homans, Steve W, Ferguson, Michael A. J, Dwek, Raymond A, Rademacher, Thomas W, Anand, Rita, Williams, Alan F

“…Glycosyl-phosphatidylinositol (GPI) anchors have recently been identified as alternatives to hydrophobic amino acid sequences for the attachment of a variety…”
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The glycoinositol phospholipids of Leishmania mexicana promastigotes. Evidence for the presence of three distinct pathways of glycolipid biosynthesis by MCCONVILLE, M. J, COLLIDGE, T. A. C, FERGUSON, M. A. J, SCHNEIDER, P

“…Most macromolecules at the cell surface of parasitic protozoa of the genus Leishmania, including the major surface glycoproteins and a complex…”
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