Search Results - "FERAMISCO, J. R"

A Requirement for Extracellular Signal-Regulated Kinase (ERK) Function in the Activation of AP-1 by Ha-Ras, Phorbol 12-Myristate 13-Acetate, and Serum by Frost, Jeffrey A., Geppert, Thomas D., Cobb, Melanie H., Feramisco, James R.

“…The role of ERK-1 and ERK-2 in wild-type (wt) Ha-Ras, phorbol 12-myristate 13-acetate (PMA), and serum-induced AP-1 activity was studied. Microinjection of…”
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HRas-dependent pathways can activate morphological and genetic markers of cardiac muscle cell hypertrophy by THORBURN, A, THORBURN, J, SEI-YU CHEN, POWERS, S, SHUBEITA, H. E, FERAMISCO, J. R, CHIEN, K. R

“…We have investigated the role of the proto-oncogene HRas in cardiac cell growth and hypertrophy. By direct needle microinjection of activated Ras protein into…”
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Regulation of Cell Cycle Progression and Nuclear Affinity of the Retinoblastoma Protein by Protein Phosphatases by Alberts, Arthur S., Thorburn, Andrew M., Shenolikar, Shirish, Mumby, Marc C., Feramisco, James R.

“…Decreased affinity of the retinoblastoma protein (RB) for the nuclear compartment has been correlated with cell cycle-dependent phosphorylation of the RB…”
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Rapid purification of mammalian 70,000-dalton stress proteins: affinity of the proteins for nucleotides by WELCH, W. J, FERAMISCO, J. R

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Nuclear and nucleolar localization of the 72,000-dalton heat shock protein in heat-shocked mammalian cells by Welch, W J, Feramisco, J R

“…The intracellular location of the major induced mammalian heat shock (or stress) protein (Mr = 72,000) has been determined by both biochemical and…”
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Regulation of Actin Microfilament Integrity in Living Nonmuscle Cells by the cAMP-Dependent Protein Kinase and the Myosin Light Chain Kinase by Ned J. C. Lamb, Fernandez, Anne, Conti, Mary Anne, Adelstein, Robert, Glass, David B., Welch, William J., Feramisco, James R.

“…Microinjection of the catalytic subunit of cAMP-dependent protein kinase (A-kinase) into living fibroblasts or the treatment of these cells with agents that…”
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A Rab1 Mutant Affecting Guanine Nucleotide Exchange Promotes Disassembly of the Golgi Apparatus by Wilson, Bridget S., Nuoffer, Claude, Meinkoth, Judy L., McCaffery, Michael, Feramisco, James R., Balch, William E., Farquhar, Marilyn Gist

“…The Golgi apparatus is a dynamic organelle whose structure is sensitive to vesicular traffic and to cell cycle control. We have examined the potential role for…”
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Microinjection of fos-specific antibodies blocks DNA synthesis in fibroblast cells by RIABOWOL, K. T, VOSATKA, R. J, ZIFF, E. B, LAMB, N. J, FERAMISCO, J. R

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Dynamics of the Distribution of Cyclic AMP-Dependent Protein Kinase in Living Cells by Meinkoth, Judy L., Ji, Ying, Taylor, Susan S., Feramisco, James R.

“…The intracellular distribution of regulatory molecules may provide a mechanism for controlling gene expression. The subcellular location of cAMP-dependent…”
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Mediation of Growth Factor Induced DNA Synthesis and Calcium Mobilization by Gq and Gi2 by LaMorte, V. J., Harootunian, A. T., Spiegel, A. M., Tsien, R. Y., Feramisco, J. R.

“…A newly identified subclass of the heterotrimeric GTP binding regulatory protein family, Gq, has been found to be expressed in a diverse range of cell types…”
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Modulation of Vimentin Containing Intermediate Filament Distribution and Phosphorylation in Living Fibroblasts by the cAMP-Dependent Protein Kinase by Ned J. C. Lamb, Fernandez, Anne, Feramisco, James R., Welch, William J.

“…Microinjection of the purified catalytic subunit of the cAMP-dependent protein kinase (A-kinase) into living rat embryo fibroblasts leads to dramatic changes…”
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The common 90‐kd protein component of non‐transformed ‘8S’ steroid receptors is a heat‐shock protein by Catelli, M.G., Binart, N., Jung‐Testas, I., Renoir, J.M., Baulieu, E.E., Feramisco, J.R., Welch, W.J.

“…Non‐transformed steroid receptors have an approximately 8S sedimentation coefficient that corresponds to an oligomeric structure of 250‐300 kd which includes a…”
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Recombinant cyclic AMP response element binding protein (CREB) phosphorylated on Ser-133 is transcriptionally active upon its introduction into fibroblast nuclei by ALBERTS, A. S, ARIAS, J, HAGIWARA, M, MONTMINY, M. R, FERAMISCO, J. R

“…To date, it has not been possible to determine whether the single phosphorylation of the cyclic AMP response element binding factor (CREB) at Ser-133 is…”
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RB-Dependent S-Phase Response to DNA Damage by Knudsen, Karen E., Booth, Dana, Naderi, Soheil, Sever-Chroneos, Zvjezdana, Fribourg, Anne F., Hunton, Irina C., Feramisco, James R., Wang, Jean Y. J., Knudsen, Erik S.

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Transport of microinjected proteins into peroxisomes of mammalian cells: inability of Zellweger cell lines to import proteins with the SKL tripeptide peroxisomal targeting signal by WALTON, P. A, GOULD, S. J, FERAMISCO, J. R, SUBRAMANI, S

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Purification of the major mammalian heat shock proteins by Welch, W J, Feramisco, J R

“…The major mammalian heat shock or "stress" proteins (molecular masses of 90,000, 72,000, and 73,000 daltons) have been purified from stressed HeLa cells. The…”
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10-nm Filaments Are Induced to Collapse in Living Cells Microinjected with Monoclonal and Polyclonal Antibodies against Tubulin by Blose, Stephen H., Meltzer, Donna I., Feramisco, James R.

“…Cells were microinjected with four mouse monoclonal antibodies that were directed against either alpha- or beta-tubulin subunits, one monoclonal with activity…”
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Protein phosphatase 2A potentiates activity of promoters containing AP-1-binding elements by Alberts, A S, Deng, T, Lin, A, Meinkoth, J L, Schönthal, A, Mumby, M C, Karin, M, Feramisco, J R

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A requirement for Ras protein function in thrombin-stimulated mitogenesis in astrocytoma cells by LAMORTE, V. J, KENNEDY, E. D, COLLINS, L. R, GOLDSTEIN, D, HAROOTUNIAN, A. T, BROWN, J. H, FERAMISCO, J. R

“…Thrombin stimulation of 1321N1 astrocytoma cells results in polyphosphoinositide hydrolysis, Ca2+ mobilization, AP-1-mediated transcriptional activation, and…”
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A rapid purification of alpha-actinin, filamin, and a 130,000-dalton protein from smooth muscle by Feramisco, J R, Burridge, K

“…Brief, low ionic strength extraction of chicken gizzard at 37 degrees C yields a solution containing a limited number of proteins including alpha-actinin,…”
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