Search Results - "FEHRER, CHRISTINE"
-
1
Biosynthesis of a D-Amino Acid in Peptide Linkage by an Enzyme from Frog Skin Secretions
Published in Proceedings of the National Academy of Sciences - PNAS (22-03-2005)“…D-amino acids are present in some peptides from amphibian skin. These residues are derived from the corresponding L-amino acids present in the respective…”
Get full text
Journal Article -
2
Leptin receptor/CD295 is upregulated on primary human mesenchymal stem cells of advancing biological age and distinctly marks the subpopulation of dying cells
Published in Experimental gerontology (01-01-2009)“…During the lifetime of an adult organism, stem cells face extrinsic and intrinsic aging. Mesenchymal stem cells (MSC) can be expanded in culture, and the…”
Get full text
Journal Article -
3
Mesenchymal stem cell aging
Published in Experimental gerontology (01-12-2005)“…Stem cells are located throughout the adult body of higher organisms, supporting a continuous renewal and repair of tissues. Unique abilities of stem cells are…”
Get full text
Journal Article -
4
Reduced oxygen tension attenuates differentiation capacity of human mesenchymal stem cells and prolongs their lifespan
Published in Aging cell (01-12-2007)“…Summary Mesenchymal stem cells (MSC) are capable of differentiating into bone, fat, cartilage, tendon and other organ progenitor cells. Despite the abundance…”
Get full text
Journal Article -
5
Aging of Murine Mesenchymal Stem Cells
Published in Annals of the New York Academy of Sciences (01-05-2006)“…: Mesenchymal stem cells (MSCs) are able to differentiate into distinct lineages such as adipo‐, osteo‐, and chondrocytes. MSCs were isolated from three mouse…”
Get full text
Journal Article -
6
Age-associated functional changes of human mesenchymal stem cells
Published in Experimental gerontology (01-02-2011)Get full text
Journal Article -
7
Strong binding of bioactive BMP-2 to nanocrystalline diamond by physisorption
Published in Biomaterials (01-09-2006)“…Nano-crystalline diamond (NCD)-coated surfaces were efficiently functionalized with bone morphogenetic protein-2 (BMP-2) by means of physisorption. Due to…”
Get full text
Journal Article -
8
Age-specific changes of mesenchymal stem cells are paralleled by upregulation of CD106 expression as a response to an inflammatory environment
Published in Rejuvenation research (01-04-2011)“…Regeneration, tissue remodeling, and organ repair after injury, which rely on the regulated activity of tissue-borne stem cells, become increasingly…”
Get more information
Journal Article -
9
Mouse testicular hyaluronidase-like proteins SPAM1 and HYAL5 but not HYALP1 degrade hyaluronan
Published in Biochemical journal (01-01-2007)“…Besides SPAM1 (sperm adhesion molecule 1; formerly named PH-20), further hyaluronidase-like proteins, HYAL5 (hyaluronoglucosaminidase 5) and HYALP1…”
Get full text
Journal Article -
10
High-yield recombinant expression of the extremophile enzyme, bee hyaluronidase in Pichia pastoris
Published in Protein expression and purification (01-02-2008)“…Hyaluronidase from honey bee was recombinantly expressed as a secreted glycoprotein in Pichia pastoris. The active enzyme was produced in milligram quantities…”
Get full text
Journal Article -
11
CD25-Expressing CD8+ T Cells Are Potent Memory Cells in Old Age
Published in The Journal of immunology (1950) (01-08-2005)“…We have recently described an IL-2/IL-4-producing CD8+CD25+ non-regulatory memory T cell population that occurs in a subgroup of healthy elderly persons who…”
Get full text
Journal Article -
12
Techniques in gerontology: Cell lines as standards for telomere length and telomerase activity assessment
Published in Experimental gerontology (01-06-2006)“…The length of telomeres is believed to critically influence cellular aging processes and disease development. In order to reliably monitor telomere length and…”
Get full text
Journal Article -
13
lin-Sca-1+ cells and age-dependent changes of their proliferation potential are reliant on mesenchymal stromal cells and are leukemia inhibitory factor dependent
Published in Gerontology (Basel) (01-01-2008)“…Aging as a process is paralleled by a variety of hematological alterations. Characteristic features are a diminished homeostatic control of blood cell…”
Get more information
Journal Article -
14
CD25-Expressing CD8 super(+) T Cells Are Potent Memory Cells in Old Age
Published in The Journal of immunology (1950) (01-08-2005)“…We have recently described an IL-2/IL-4-producing CD8 super(+)CD25 super(+) nonregulatory memory T cell population that occurs in a subgroup of healthy elderly…”
Get full text
Journal Article