Search Results - "FEDERICO PERNO, Carlo"

Diagnostic performance of molecular and serological tests of SARS-CoV-2 on well-characterised specimens from COVID-19 individuals: The EDCTP "PERFECT-study" protocol (RIA2020EF-3000) by Fokam, Joseph, Alteri, Claudia, Colagrossi, Luna, Genevieve, Anne-Marie, Takou, Désiré, Ndjolo, Alexis, Colizzi, Vittorio, Ndembi, Nicaise, Perno, Carlo-Federico

“…The SARS-CoV-2 pandemic is a global threat affecting 210 countries, with 2,177,469 confirmed cases and 6.67% case fatality rate as of April 16, 2020. In…”
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Twenty-Five Years of Lamivudine: Current and Future Use for the Treatment of HIV-1 Infection by Quercia, Romina, Perno, Carlo-Federico, Koteff, Justin, Moore, Katy, McCoig, Cynthia, St. Clair, Marty, Kuritzkes, Daniel

“…ABSTRACTInnovation in medicine is a dynamic, complex, and continuous process that cannot be isolated to a single moment in time. Anniversaries offer…”
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Hepatitis B surface antigen genetic elements critical for immune escape correlate with hepatitis B virus reactivation upon immunosuppression by Salpini, Romina, Colagrossi, Luna, Bellocchi, Maria Concetta, Surdo, Matteo, Becker, Christina, Alteri, Claudia, Aragri, Marianna, Ricciardi, Alessandra, Armenia, Daniele, Pollicita, Michela, Di Santo, Fabiola, Carioti, Luca, Louzoun, Yoram, Mastroianni, Claudio Maria, Lichtner, Miriam, Paoloni, Maurizio, Esposito, Mariarosaria, D'Amore, Chiara, Marrone, Aldo, Marignani, Massimo, Sarrecchia, Cesare, Sarmati, Loredana, Andreoni, Massimo, Angelico, Mario, Verheyen, Jens, Perno, Carlo‐Federico, Svicher, Valentina

“…Hepatitis B virus (HBV) reactivation during immunosuppression can lead to severe acute hepatitis, fulminant liver failure, and death. Here, we investigated…”
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Global burden of SARS-CoV-2 infection, hospitalization and case fatality rate among COVID-19 vaccinated individuals and its associated factors: A systematic review and meta-analysis protocol by Nka, Alex Durand, Ka'e, Aude Christelle, Bouba, Yagai, Ngoufack Jagni Semengue, Ezechiel, Tommo Tchouaket, Michel Carlos, Takou, Désiré, Pabo, Willy, Fainguem, Nadine, Sosso, Samuel Martin, Colizzi, Vittorio, Perno, Carlo-Federico, Fokam, Joseph

“…Background COVID-19 has been the most important public health concern worldwide since 2020. Several vaccines are now available to help in controlling COVID-19…”
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Evaluation of archived drug resistance mutations in HIV‐1 DNA among vertically infected adolescents under antiretroviral treatment in Cameroon: Findings during the COVID‐19 pandemic by Ka'e, Aude Christelle, Fokam, Joseph, Togna Pabo, Willy Le Roi, Nanfack, Aubin, Ngoufack Jagni Semengue, Ezechiel, Bouba, Yagai, Nka, Alex Durand, Tetang, Suzie, Beloumou, Grace, Takou, Desire, Chenwi, Collins, Tommo Tchouaket, Michel Carlos, Abba, Aissatou, Djupsa, Sandrine, Sosso, Samuel Martin, Pamen, Nounouce Bouba, Otshudiema, John O., Boum, Yap, Colizzi, Vittorio, Ndjolo, Alexis, Perno, Carlo‐Federico, Ceccherini‐Silberstein, Francesca, Santoro, Maria M.

“…Background With the success of antiretroviral therapy (ART), children born with HIV are more likely to reach adolescence. However, frequent non‐adherence to…”
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Detection of Gag C-terminal mutations among HIV-1 non-B subtypes in a subset of Cameroonian patients by Teto, Georges, Nka, Alex Durand, Fokam, Joseph, Bouba, Yagai, Takou, Désiré, Fabeni, Lavinia, Carioti, Luca, Armenia, Daniele, Semengue, Ezéchiel Ngoufack Jagni, Dambaya, Béatrice, Sosso, Samuel Martin, Colizzi, Vittorio, Perno, Carlo-Federico, Ceccherini-Silberstein, Francesca, Santoro, Maria Mercedes, Ndjolo, Alexis

“…Response to ritonavir-boosted-protease inhibitors (PI/r)-based regimen is associated with some Gag mutations among HIV-1 B-clade. There is limited data on Gag…”
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HIV-1 Gag gene mutations, treatment response and drug resistance to protease inhibitors: A systematic review and meta-analysis protocol by Nka, Alex Durand, Teto, Georges, Santoro, Maria Mercedes, Ngum Ndze, Valantine, Takou, Désiré, Dambaya, Beatrice, Ngoufack Jagni Semengue, Ezechiel, Fabeni, Lavinia, Perno, Carlo-Federico, Colizzi, Vittorio, Ceccherini-Silberstein, Francesca, Fokam, Joseph

“…Some mutations in the HIV-1 Gag gene are known to confer resistance to ritonavir-boosted protease inhibitors (PI/r), but their clinical implications remain…”
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A snapshot of virological presentation and outcome of immunosuppression‐driven HBV reactivation from real clinical practice: Evidence of a relevant risk of death and evolution from silent to chronic infection by Salpini, Romina, Battisti, Arianna, Colagrossi, Luna, Di Carlo, Domenico, Fabeni, Lavinia, Piermatteo, Lorenzo, Cerva, Carlotta, Lichtner, Miriam, Mastroianni, Claudio, Marignani, Massimo, Maylin, Sarah, Delaugerre, Constance, Morisco, Filomena, Coppola, Nicola, Marrone, Aldo, Angelico, Mario, Sarmati, Loredana, Andreoni, Massimo, Perno, Carlo‐Federico, Ceccherini‐Silberstein, Francesca, Svicher, Valentina, Bertoli, Ada, Fini, Vanessa, Pollicita, Michela, Salpini, Romina, Maffongelli, Gaetano, Ricciardi, Alessandra, Sarrecchia, Cesare, Baiocchi, Leonardo, Brega, Arianna, Daniele Di Paolo, Francioso, Simona, Lenci, Ilaria, Arcese, William, Cudillo, Laura, Mariotti, Benedetta, Claudio Miriam Lichtner, Marocco, Raffaella, Mastroianni, Maria, Taliani, Gloria, Tieghi, Tiziana, Esposito, Maria Rosaria, Mari, Terenzio, Mazzoni, Ettore, Spaziani, Fabrizio, Casinelli, Katia, Paoloni, Maurizio, Iapadre, Nerio, Grimaldi, Alessandro, Begini, Paola, Imperatrice, Barbara, Vanvitelli, Luigi, Macera, Margherita, Pisaturo, Mariantonietta, Vanvitelli, Luigi, more, Chiara, Siniscalchi, Isabella, Esposito, Maria Rosaria

“…The study was undertaken in order to provide a snapshot from real clinical practice of virological presentation and outcome of patients developing…”
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Pre-treatment drug resistance and HIV-1 genetic diversity in the rural and urban settings of Northwest-Cameroon by Fokam, Joseph, Takou, Desire, Teto, Georges, Nforbih, Shu E, Kome, Odine P, Santoro, Maria M, Ngoufack, Ezechiel S, Eyongetah, Mbuh, Palmer, Denis, Fokunang, Estella T, Fokunang, Charles N, Colizzi, Vittorio, Perno, Carlo-Federico, Ndjolo, Alexis, Ceccherini-Silberstein, Francesca

“…Background With the scale-up of antiretroviral therapy (ART), pre-treatment drug resistance (PDR) appears [greater than or equal to]10% amongst ART-initiators…”
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Characterisation of HIV-1 reservoirs in paediatric populations: protocol for a systematic review and meta-analysis by Ka’e, Aude Christelle, Nanfack, Aubin, Santoro, Maria-Mercedes, Yagai, Bouba, Ambada, Georgia, Sagnia, Bertrand, Nka, Alex Durand, Ngoufack Jagni Semengue, Ezechiel, Pabo, Willy, Takou, Désiré, Sonela, Nelson, Colizzi, Vittorio, Perno, Carlo-Federico, Ceccherini-Silberstein, Francesca, Lewin, Sharon R, Tiemessen, Caroline T, Fokam, Joseph

“…IntroductionThe success of antiretroviral therapy (ART) has changed HIV from a deadly to a chronic infection, thus increasing the transitioning from infancy…”
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Pre-existing immunity to SARS-CoV-2 before the COVID-19 pandemic era in Cameroon: A comparative analysis according to HIV-status by Aissatou, Abba, Fokam, Joseph, Semengue, Ezechiel Ngoufack Jagni, Takou, Désiré, Ka'e, Aude Christelle, Ambe, Collins Chenwi, Nka, Alex Durand, Djupsa, Sandrine Claire, Beloumou, Grâce, Ciaffi, Laura, Tchouaket, Michel Carlos Tommo, Nayang, Audrey Rachel Mundo, Pabo, Willy Leroi Togna, Essomba, René Ghislain, Halle, Edie G E, Okomo, Marie-Claire, Bissek, Anne-Cecile Zk, Leke, Rose, Boum, 2nd, Yap, Mballa, Georges Alain Etoundi, Montesano, Carla, Perno, Carlo-Federico, Colizzi, Vittorio, Ndjolo, Alexis

“…The lower burden of COVID-19 in tropical settings may be due to preexisting cross-immunity, which might vary according to geographical locations and potential…”
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Laboratory Based Surveillance of HIV-1 Acquired Drug Resistance in Cameroon: Implications for Use of Tenofovir-Lamivudine-Dolutegravir (TLD) as Second- or Third-Line Regimens by Fokam, Joseph, Chenwi, Collins Ambe, Takou, Desire, Santoro, Maria Mercedes, Tala, Valere, Teto, George, Beloumou, Grace, Semengue, Ezechiel Ngoufack Jagni, Dambaya, Beatrice, Djupsa, Sandrine, Kembou, Etienne, Bouba, Nounouce Pamen, Ajeh, Rogers, Cappelli, Giulia, Mbanya, Dora, Colizzi, Vittorio, Ceccherini-Silberstein, Francesca, Perno, Carlo-Federico, Ndjolo, Alexis

“…Increased HIV drug resistance (HIVDR) with antiretroviral therapy (ART) rollout may jeopardize therapeutic options, especially in this era of transition to…”
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Pre-Treatment HIV Drug Resistance and Genetic Diversity in Cameroon: Implications for First-Line Regimens by Fokam, Joseph, Chenwi, Collins Ambe, Tala, Valère, Takou, Désiré, Santoro, Maria Mercedes, Teto, George, Dambaya, Beatrice, Anubodem, Felix, Semengue, Ezechiel Ngoufack Jagni, Beloumou, Grace, Djupsa, Sandrine, Assomo, Edgar, Fokunang, Charles, Alteri, Claudia, Billong, Serge, Bouba, Nounouce Pamen, Ajeh, Rogers, Colizzi, Vittorio, Mbanya, Dora, Ceccherini-Silberstein, Francesca, Perno, Carlo-Federico, Ndjolo, Alexis

“…The efficacy of first-line antiretroviral therapy (ART) may be hampered by the presence of HIV drug resistance (HIVDR). We described HIV-1 pre-treatment drug…”
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Viral suppression in adults, adolescents and children receiving antiretroviral therapy in Cameroon: adolescents at high risk of virological failure in the era of "test and treat" by Fokam, Joseph, Sosso, Samuel Martin, Yagai, Bouba, Billong, Serge Clotaire, Djubgang Mbadie, Rina Estelle, Kamgaing Simo, Rachel, Edimo, Serge Valery, Nka, Alex Durand, Tiga Ayissi, Aline, Yimga, Junie Flore, Takou, Désiré, Moudourou, Sylvie, Ngo Nemb, Marinette, Nfetam Elat, Jean-Bosco, Santoro, Maria-Mercedes, Perno, Carlo-Federico, Colizzi, Vittorio, Ndjolo, Alexis

“…After the launching of the « Test & Treat » strategy and the wider accessibility to viral load (VL), evaluating virological success (VS) would help in meeting…”
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HIV-1 drug resistance testing is essential for heavily-treated patients switching from first- to second-line regimens in resource-limited settings: evidence from routine clinical practice in Cameroon by Takou, Desire, Fokam, Joseph, Teto, Georges, Santoro, Maria-Mercedes, Ceccherini-Silberstein, Francesca, Nanfack, Aubin Joseph, Sosso, Samuel Martin, Dambaya, Béatrice, Salpini, Romina, Billong, Serge Clotaire, Gori, Caterina, Fokunang, Charles Ntungwen, Cappelli, Giulia, Colizzi, Vittorio, Perno, Carlo-Federico, Ndjolo, Alexis

“…With the phase-out of stavudine (d4T), change to first-line regimens with zidovudine (AZT) or tenofovir (TDF) in resource-limited settings (RLS) might increase…”
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Evaluation of treatment response, drug resistance and HIV-1 variability among adolescents on first- and second-line antiretroviral therapy: a study protocol for a prospective observational study in the centre region of Cameroon (EDCTP READY-study) by Fokam, Joseph, Santoro, Maria Mercedes, Takou, Desire, Njom-Nlend, Anne-Esther, Ndombo, Paul Koki, Kamgaing, Nelly, Kamta, Cedric, Essiane, Andre, Sosso, Samuel Martin, Ndjolo, Alexis, Colizzi, Vittorio, Perno, Carlo-Federico

“…Sub-Saharan Africa (SSA) alone has nine out of every 10 children living with HIV globally and monitoring in this setting remains suboptimal, even as these…”
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Study of Genotypic and Phenotypic HIV-1 Dynamics of Integrase Mutations During Raltegravir Treatment: A Refined Analysis by Ultra-Deep 454 Pyrosequencing by Armenia, Daniele, Vandenbroucke, Ina, Fabeni, Lavinia, Van Marck, Herwig, Cento, Valeria, D'Arrigo, Roberta, Van Wesenbeeck, Liesbeth, Scopelliti, Fernanda, Micheli, Valeria, Bruzzone, Bianca, Caputo, Sergio Lo, Aerssens, Jeroen, Rizzardini, Giuliano, Tozzi, Valerio, Narciso, Pasquale, Antinori, Andrea, Stuyver, Lieven, Perno, Carlo Federico, Ceccherini-Silberstein, Francesca

“…Background. The dynamics of raltegravir-resistant variants and their impact on virologie response in 23 HIV-1-infected patients, who started a salvage…”
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Overcoming resistance to existing therapies in HIV-infected patients: The role of new antiretroviral drugs by Perno, Carlo-Federico, Moyle, Graeme, Tsoukas, Chris, Ratanasuwan, Winai, Gatell, Jose, Schechter, Mauro

“…Resistance to available antiretroviral (ARV) agents is of increasing concern, and development of novel agents that address this problem has been identified as…”
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Programme quality indicators of HIV drug resistance among adolescents in urban versus rural settings of the centre region of Cameroon by Fokam, Joseph, Nangmo, Armanda, Wandum, Carlson, Takou, Desire, Santoro, Maria Mercedes, Nlend, Anne-Esther Njom, Ateba, Francis Ndongo, Ndombo, Paul Koki, Kamgaing, Nelly, Kamta, Cedric, Essiane, Andre, Lambo, Virginie, Fokunang, Charles, Mbanya, Dora, Colizzi, Vittorio, Perno, Carlo-Federico, Ndjolo, Alexis

“…The high rate of mortality among HIV-vertically infected adolescents might be favoured by HIV drug resistance (HIVDR) emergence, which calls for timeous…”
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Identification of Merkel cell polyomavirus in the lower respiratory tract of Italian patients by Babakir-Mina, Muhammed, Ciccozzi, Massimo, Lo Presti, Alessandra, Greco, Francesco, Perno, Carlo Federico, Ciotti, Marco

“…Merkel cell polyomavirus (MCPyV) has been found to be integrated monoclonally in a rare skin cancer named Merkel cell carcinoma. More recently, MCPyV has been…”
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