Search Results - "FAZIO, Leonardo"
-
1
Multivariate classification of schizophrenia and its familial risk based on load-dependent attentional control brain functional connectivity
Published in Neuropsychopharmacology (New York, N.Y.) (01-03-2020)“…Patients with schizophrenia (SCZ), as well as their unaffected siblings (SIB), show functional connectivity (FC) alterations during performance of tasks…”
Get full text
Journal Article -
2
Polymorphisms in human dopamine D2 receptor gene affect gene expression, splicing, and neuronal activity during working memory
Published in Proceedings of the National Academy of Sciences - PNAS (18-12-2007)“…Subcortical dopamine D2 receptor (DRD2) signaling is implicated in cognitive processes and brain disorders, but the effect of DRD2 variants remains ambiguous…”
Get full text
Journal Article -
3
Emotion-body connection dispositions modify the insulae-midcingulate effective connectivity during anger processing
Published in PloS one (13-02-2020)“…The link between anger and bodily states is readily apparent based on the autonomic and behavioral responses elicited. In everyday life angry people react in…”
Get full text
Journal Article -
4
A generative-discriminative framework that integrates imaging, genetic, and diagnosis into coupled low dimensional space
Published in NeuroImage (Orlando, Fla.) (01-09-2021)“…We propose a novel optimization framework that integrates imaging and genetics data for simultaneous biomarker identification and disease classification. The…”
Get full text
Journal Article -
5
Association between Ability Emotional Intelligence and Left Insula during Social Judgment of Facial Emotions
Published in PloS one (09-02-2016)“…The human ability of identifying, processing and regulating emotions from social stimuli is generally referred as Emotional Intelligence (EI). Within EI,…”
Get full text
Journal Article -
6
Illness-related variables and abnormalities of resting-state brain activity in schizophrenia
Published in Frontiers in psychiatry (06-08-2024)“…The development of neuroimaging biomarkers in patients with schizophrenia (SCZ) requires a refined clinical characterization. A limitation of the neuroimaging…”
Get full text
Journal Article -
7
Understanding the relationship between childhood emotional abuse and neglect and psychological distress in pregnant women: the role of prenatal attachment
Published in BMC Psychology (01-10-2024)“…Childhood abuse and neglect pose important risk factors for the development of psychopathology during pregnancy. However, only a few studies have assessed the…”
Get full text
Journal Article -
8
Ruminative thinking mediates the effects of exposure to adverse life events on psychotic-like experiences
Published in Frontiers in psychology (12-11-2024)“…Introduction:A growing literature has shown that exposure to adverse life events during childhood or adolescence is associated with the presence of…”
Get full text
Journal Article -
9
Genetic control of variability in subcortical and intracranial volumes
Published in Molecular psychiatry (01-08-2021)“…Sensitivity to external demands is essential for adaptation to dynamic environments, but comes at the cost of increased risk of adverse outcomes when facing…”
Get full text
Journal Article -
10
Functional variants of the dopamine receptor D2 gene modulate prefronto-striatal phenotypes in schizophrenia
Published in Brain (London, England : 1878) (01-02-2009)“…Dopamine D2 receptor signalling is strongly implicated in the aetiology of schizophrenia. We have recently characterized the function of three DRD2 SNPs:…”
Get full text
Journal Article -
11
Rasd2 Modulates Prefronto-Striatal Phenotypes in Humans and 'Schizophrenia-Like Behaviors' in Mice
Published in Neuropsychopharmacology (New York, N.Y.) (01-02-2016)“…Rasd2 is a thyroid hormone target gene, which encodes for a GTP-binding protein enriched in the striatum where, among other functions, it modulates…”
Get full text
Journal Article -
12
DRD2/AKT1 interaction on D2 c-AMP independent signaling, attentional processing, and response to olanzapine treatment in schizophrenia
Published in Proceedings of the National Academy of Sciences - PNAS (18-01-2011)“…The D2/AKT1/GSK-3β signaling pathway has been involved in the downstream intracellular effects of dopamine, in the pathophysiology of cognitive deficits and…”
Get full text
Journal Article -
13
Prefrontal Activity and Connectivity with the Basal Ganglia during Performance of Complex Cognitive Tasks Is Associated with Apathy in Healthy Subjects
Published in PloS one (31-10-2016)“…Convergent evidence indicates that apathy affects cognitive behavior in different neurological and psychiatric conditions. Studies of clinical populations have…”
Get full text
Journal Article -
14
BDNF rs6265 methylation and genotype interact on risk for schizophrenia
Published in Epigenetics (02-01-2016)“…Epigenetic mechanisms can mediate gene-environment interactions relevant for complex disorders. The BDNF gene is crucial for development and brain plasticity,…”
Get full text
Journal Article -
15
Genetically determined measures of striatal D2 signaling predict prefrontal activity during working memory performance
Published in PloS one (22-02-2010)“…Variation of the gene coding for D2 receptors (DRD2) has been associated with risk for schizophrenia and with working memory deficits. A functional intronic…”
Get full text
Journal Article -
16
Resting-State Brain Activity Dysfunctions in Schizophrenia and Their Associations with Negative Symptom Domains: An fMRI Study
Published in Brain sciences (01-01-2023)“…The aim of the present study was to examine the neurobiological correlates of the two negative symptom domains of schizophrenia, the Motivational Deficit…”
Get full text
Journal Article -
17
DRD2/CHRNA5 interaction on prefrontal biology and physiology during working memory
Published in PloS one (12-05-2014)“…Prefrontal behavior and activity in humans are heritable. Studies in animals demonstrate an interaction between dopamine D2 receptors and nicotinic…”
Get full text
Journal Article -
18
Affective response to a loved one's pain: insula activity as a function of individual differences
Published in PloS one (16-12-2010)“…Individual variability in emotion processing may be associated with genetic variation as well as with psychological predispositions such as dispositional…”
Get full text
Journal Article -
19
Expression of DISC1-interactome members correlates with cognitive phenotypes related to schizophrenia
Published in PloS one (18-06-2014)“…Cognitive dysfunction is central to the schizophrenia phenotype. Genetic and functional studies have implicated Disrupted-in-Schizophrenia 1 (DISC1), a leading…”
Get full text
Journal Article -
20
Activity in medial prefrontal cortex during cognitive evaluation of threatening stimuli as a function of personality style
Published in Brain research bulletin (28-09-2007)“…Abstract Cognitive evaluation of emotional stimuli involves a network of brain regions including the medial prefrontal cortex (mPFC). However, threatening…”
Get full text
Journal Article