Search Results - "FAVEREAUX, Alexandre"
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Emerging Roles of Extracellular Vesicles in the Central Nervous System: Physiology, Pathology, and Therapeutic Perspectives
Published in Frontiers in cellular neuroscience (23-02-2021)“…Extracellular vesicles or EVs are secreted by most, if not all, eukaryote cell types and recaptured by neighboring or distant cells. Their cargo, composed of a…”
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MicroRNA and chronic pain: From mechanisms to therapeutic potential
Published in Pharmacology & therapeutics (Oxford) (01-12-2017)“…Chronic pain is a major public health issue with an incidence of 20-25% worldwide that can take different forms like neuropathic, cancer-related or…”
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miRNA-Dependent Control of Homeostatic Plasticity in Neurons
Published in Frontiers in cellular neuroscience (05-12-2019)“…Homeostatic plasticity is a form of plasticity in which neurons compensate for changes in neuronal activity through the control of key physiological parameters…”
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MDGAs are fast-diffusing molecules that delay excitatory synapse development by altering neuroligin behavior
Published in eLife (09-05-2022)“…MDGA molecules can bind neuroligins and interfere with trans-synaptic interactions to neurexins, thereby impairing synapse development. However, the…”
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LRRTM2 controls presynapse nano-organization and AMPA receptor sub-positioning through Neurexin-binding interface
Published in Nature communications (11-10-2024)“…Synapses are organized into nanocolumns that control synaptic transmission efficacy through precise alignment of postsynaptic neurotransmitter receptors and…”
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Inositol-requiring enzyme 1α is a key regulator of angiogenesis and invasion in malignant glioma
Published in Proceedings of the National Academy of Sciences - PNAS (31-08-2010)“…Inositol-requiring enzyme 1 (IRE1) is a proximal endoplasmic reticulum (ER) stress sensor and a central mediator of the unfolded protein response. In a human…”
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Bidirectional integrative regulation of Cav1.2 calcium channel by microRNA miR-103: role in pain
Published in The EMBO journal (14-09-2011)“…Chronic pain states are characterized by long‐term sensitization of spinal cord neurons that relay nociceptive information to the brain. Among the mechanisms…”
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MULTIMODAL PROFILING OF DEVELOPING PURKINJE CELLS USING PATCH SEQ
Published in IBRO neuroscience reports (01-10-2023)Get full text
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Acquisition of analgesic properties by the cholecystokinin (CCK)/CCK2 receptor system within the amygdala in a persistent inflammatory pain condition
Published in Pain (Amsterdam) (01-02-2019)“…Pain is associated with negative emotions such as anxiety, but the underlying neurocircuitry and modulators of the association of pain and anxiety remain…”
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Physical exercise restores adult neurogenesis deficits induced by simulated microgravity
Published in NPJ microgravity (21-06-2024)“…Cognitive impairments have been reported in astronauts during spaceflights and documented in ground-based models of simulated microgravity (SMG) in animals…”
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Spinal miRNA-124 regulates synaptopodin and nociception in an animal model of bone cancer pain
Published in Scientific reports (08-09-2017)“…Strong breakthrough pain is one of the most disabling symptoms of cancer since it affects up to 90% of cancer patients and is often refractory to treatments…”
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In Silico , In Vitro and In Cellulo Models for Monitoring SARS-CoV-2 Spike/Human ACE2 Complex, Viral Entry and Cell Fusion
Published in Viruses (25-02-2021)“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the etiologic agent responsible for the recent coronavirus disease 2019 (COVID-19) pandemic…”
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A NEW KNOCK-IN MOUSE MODEL TO INVESTIGATE THE SYNAPTIC LOCALIZATION OF ENDOGENOUS NEUROLIGIN-1
Published in IBRO neuroscience reports (01-10-2023)Get full text
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Group I metabotropic glutamate receptor plasticity after peripheral inflammation alters nociceptive transmission in the dorsal horn of the spinal cord in adult rats
Published in Molecular pain (01-01-2017)“…The dorsal horn of the spinal cord is a crucial site for pain transmission and modulation. Dorsal horn neurons of the spinal cord express group I metabotropic…”
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Time-restricted feeding prevents memory impairments induced by obesogenic diet consumption, via hippocampal thyroid hormone signaling
Published in Molecular metabolism (Germany) (01-12-2024)“…The early consumption of calorie-rich diet disrupts circadian rhythms and has adverse effects on memory, yet the effects of time-restricted feeding (TRF) and…”
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Spinal Inhibition of GABAB Receptors by the Extracellular Matrix Protein Fibulin-2 in Neuropathic Rats
Published in Frontiers in cellular neuroscience (15-07-2020)“…In the central nervous system, the inhibitory GABAB receptor is the archetype of heterodimeric G protein-coupled receptors (GPCRs). Receptor interaction with…”
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Classification of sharks in the Egyptian Mediterranean waters using morphological and DNA barcoding approaches
Published in PloS one (02-11-2011)“…The identification of species constitutes the first basic step in phylogenetic studies, biodiversity monitoring and conservation. DNA barcoding, i.e. the…”
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microRNAs in nociceptive circuits as predictors of future clinical applications
Published in Frontiers in molecular neuroscience (17-10-2013)“…Neuro-immune alterations in the peripheral and central nervous system play a role in the pathophysiology of chronic pain, and non-coding RNAs - and microRNAs…”
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Mitochondrial DNA-based identification of developmental stages and empty puparia of forensically important flies in Egypt
Published in Journal of forensic science and medicine (01-07-2018)“…Relying on morphology in the estimation of postmortem intervals is not always accurate for all life phases of flies, especially for immature stages. The…”
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Genetic Alterations in Primary Glioblastomas in Japan
Published in Journal of neuropathology and experimental neurology (01-01-2006)“…ABSTRACTCurrent knowledge of genetic alterations in glioblastomas is based largely on genetic analyses of tumors from mainly caucasian patients in the United…”
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