Search Results - "FAUTSCH, M. P"

Topography of neuron loss in the retinal ganglion cell layer in human glaucoma by Lei, Y, Garrahan, N, Hermann, B, Fautsch, M P, Johnson, D H, Hernandez, M R, Boulton, M, Morgan, J E

“…To determine if retinal ganglion cell (RGC) loss influences the loss of surrounding RGCs to generate clustered patterns of cell death in human glaucoma. It is…”
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Characterization of Myocilin-Myocilin Interactions by Fautsch, Michael P, Johnson, Douglas H

“…To determine whether myocilin (MYOC; also referred to as TIGR) is present as a complex in human aqueous humor, whether part of the complex formation may be due…”
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Recombinant TIGR/MYOC Increases Outflow Resistance in the Human Anterior Segment by Fautsch, Michael P, Bahler, Cindy K, Jewison, David J, Johnson, Douglas H

“…To determine the effect of human recombinant TIGR/myocilin (MYOC) protein on outflow resistance in the human anterior segment. A cDNA for MYOC was inserted…”
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Quantitative analysis of three-dimensional fibrillar collagen microstructure within the normal, aged and glaucomatous human optic nerve head by Jones, H. J., Girard, M. J., White, N., Fautsch, M. P., Morgan, J. E., Ethier, C. R., Albon, J.

“…The aim of this study was to quantify connective tissue fibre orientation and alignment in young, old and glaucomatous human optic nerve heads (ONH) to…”
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Transretinal degeneration in ageing human retina: a multiphoton microscopy analysis by Lei, Y, Garrahan, N, Hermann, B, Fautsch, M P, Johnson, D H, Hernandez, M R, Boulton, M, Morgan, J E

“…Retinal cell remodelling has been reported as a consistent feature of ageing. However, the degree to which this results in transretinal degeneration is…”
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TGFβ-Inducible Early Gene (TIEG) Also Codes for Early Growth Response α (EGRα): Evidence of Multiple Transcripts from Alternate Promoters by Fautsch, Michael P, Vrabel, Anne, Subramaniam, Malayannan, Hefferen, Theresa E, Spelsberg, Thomas C, Wieben, Eric D

“…TGFβ-inducible early gene (TIEG) and early growth response α (EGRα) are putative transcription factors based on homology to known zinc finger proteins SP1,…”
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Transcriptional regulation of the small nuclear ribonucleoprotein E protein gene. Identification of cis-acting sequences with homology to genes encoding ribosomal proteins by FAUTSCH, M. P, WIEBEN, E. D

“…The 5'-upstream region of the small nuclear ribonucleoprotein E protein (snRNP E) gene has multiple sequence similarities to elements found to be integral in…”
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Genetic modification of human trabecular meshwork with lentiviral vectors by Loewen, N, Fautsch, M P, Peretz, M, Bahler, C K, Cameron, J D, Johnson, D H, Poeschla, E M

“…Glaucoma, a group of optic neuropathies, is the leading cause of irreversible blindness. Neuronal apoptosis in glaucoma is primarily associated with high…”
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Conservation of coding and transcriptional control sequences within the snRNP E protein gene by Fautsch, M P, Thompson, M A, Holicky, E L, Schultz, P J, Hallett, J B, Wieben, E D

“…The snRNP E protein is one of several proteins associated with the U family of small nuclear RNAs that are involved in RNA processing. Isolation and…”
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Characterization of the mouse TGFβ-inducible early gene (TIEG): conservation of exon and transcriptional regulatory sequences with evidence of additional transcripts by Fautsch, Michael P., Vrabel, Anne, Rickard, David, Subramaniam, Malayannan, Spelsberg, Thomas C., Wieben, Eric D.

“…The human TGF beta Inducible Early Gene (TIEG) cDNA was originally isolated as a transcript that was rapidly induced by transforming growth factor beta (TGF…”
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Recombinant human proteinase 3, the Wegener's autoantigen, expressed in HMC-1 cells is enzymatically active and recognized by c-ANCA by Specks, Ulrich, Fass, David N., Fautsch, Michael P., Hummel, Amber M., Viss, Margaret A.

“…We developed a stable expression system for conformationally intact recombinant human PR3 (rPR3) using the human mast cell line HMC-1. Like in U937 cells, the…”
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Exons lost and found. Unusual evolution of a seminal vesicle transglutaminase substrate by Hagstrom, J E, Fautsch, M P, Perdok, M, Vrabel, A, Wieben, E D

“…The GP1G gene codes for three of the four abundant androgen-regulated secretory proteins produced by the guinea pig seminal vesicle. Sequencing of the entire…”
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Cyclin-dependent kinase 5 is expressed in both Sertoli cells and metaphase spermatocytes by Session, D R, Fautsch, M P, Avula, R, Jones, W R, Nehra, A, Wieben, E D

“…To gain insight into the function of cyclin-dependent kinase 5 (Cdk5) in spermatogenesis. The expression of the Cdk5 protein was determined with the use of…”
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Dissociation of p34cdc2 complex formation from phosphorylation and histone H1 kinase activity by EBLEN, S. T, FAUTSCH, M. P, BURNETTE, R. J, SNYDER, M, LEOF, E. B

“…The cell cycle inhibitor mimosine was used to examine the activation of the p34cdc2 protein kinase in S phase of the cell cycle. Addition of mimosine to…”
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Production of SVP-1/-3/-4 in guinea pig testis. Characterization of novel transcripts containing long 5'-untranslated regions and multiple upstream AUG codons by Fautsch, M P, Perdok, M M, Wieben, E D

“…The GP1G gene of the guinea pig codes for three of the four abundant seminal vesicle secretory proteins produced in this species. This gene is expressed at…”
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Effects of Intense Pulsed Light on Tear Film TGF-β and Microbiome in Ocular Rosacea with Dry Eye by Sagaser, Samantha, Butterfield, Richard, Kosiorek, Heidi, Kusne, Yael, Maldonado, Juan, Fautsch, Michael P, Patel, Dharmendra, Shen, Joanne F

“…To assess tear film transforming growth factor-beta (TGF-β) and ocular microbiome changes after intense pulsed light with meibomian gland expression (IPL-MGX)…”
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Midget retinal ganglion cell dendritic and mitochondrial degeneration is an early feature of human glaucoma by Tribble, James R, Vasalauskaite, Asta, Redmond, Tony, Young, Robert D, Hassan, Shoaib, Fautsch, Michael P, Sengpiel, Frank, Williams, Pete A, Morgan, James E

“…Glaucoma is characterized by the progressive dysfunction and loss of retinal ganglion cells. However, the earliest degenerative events that occur in human…”
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Conditional binding to and cell cycle-regulated inhibition of cyclin-dependent kinase complexes by p27Kip1 by EBLEN, S. T, FAUTSCH, M. P, ANDERS, R. A, LEOF, E. B

“…Mammalian cultures primarily regulate cell cycle traverse during G1. For progression through G1 and commitment to DNA synthesis, the activity of a family of…”
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The identification of myocilin-associated proteins in the human trabecular meshwork by Fautsch, Michael P., Vrabel, Anne M., Johnson, Douglas H.

“…Myocilin forms high molecular weight complexes in vivo presumably due to interaction with itself and other myocilin binding proteins. To identify myocilin…”
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Perfusion of His-Tagged Eukaryotic Myocilin Increases Outflow Resistance in Human Anterior Segments in the Presence of Aqueous Humor by Fautsch, Michael P, Bahler, Cindy K, Vrabel, Anne M, Howell, Kyle G, Loewen, Nils, Teo, Wulin L, Poeschla, Eric M, Johnson, Douglas H

“…A previous study by the authors has shown that recombinant myocilin purified from a prokaryotic expression system increases outflow resistance in cultured…”
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