Search Results - "FATTORUSSO, Ernesto"
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Isolation and Structure Elucidation of Ovatoxin-a, the Major Toxin Produced by Ostreopsis ovata
Published in Journal of the American Chemical Society (25-01-2012)“…Since 2005, the benthic dinoflagellate Ostreopsis cf. ovata has bloomed across the Mediterranean basin, provoking serious toxic outbreaks. LC/MS studies have…”
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2
Marine antimalarials
Published in Marine Drugs (23-04-2009)“…Malaria is an infectious disease causing at least 1 million deaths per year, and, unfortunately, the chemical entities available to treat malaria are still too…”
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3
Alkaloids from Marine Ascidians
Published in Molecules (01-10-2011)“…About 300 alkaloid structures isolated from marine ascidians are discussed in term of their occurrence, structural type and reported pharmacological activity…”
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4
Influence of temperature and salinity on Ostreopsis cf. ovata growth and evaluation of toxin content through HR LC-MS and biological assays
Published in Water research (Oxford) (2012)“…In the Mediterranean Sea, blooms of Ostreopsis cf. ovata and Ostreopsis siamensis have become increasingly frequent in the last decade and O. cf. ovata was…”
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5
Complex palytoxin-like profile of Ostreopsis ovata. Identification of four new ovatoxins by high-resolution liquid chromatography/mass spectrometry
Published in Rapid communications in mass spectrometry (30-09-2010)“…Over the past decades, Italian coastlines have been plagued by recurring presence of the benthic dinoflagellate Ostreopsis ovata. Such an alga has caused…”
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6
Tedarenes A and B: Structural and Stereochemical Analysis of Two New Strained Cyclic Diarylheptanoids from the Marine Sponge Tedania ignis
Published in Journal of organic chemistry (03-08-2012)“…Ring strain causes planar chirality in tedarenes A and B, two cyclic diarylheptanoids isolated from the marine sponge Tedania ignis. In both molecules, the…”
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7
New insights on cytological and metabolic features of Ostreopsis cf. ovata Fukuyo (Dinophyceae): a multidisciplinary approach
Published in PloS one (27-02-2013)“…The harmful dinoflagellate Ostreopsis cf. ovata has been causing toxic events along the Mediterranean coasts and other temperate and tropical areas, with…”
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8
Comparative growth and toxin profile of cultured Ostreopsis ovata from the Tyrrhenian and Adriatic Seas
Published in Toxicon (Oxford) (01-02-2010)“…Massive blooms of the benthic dinoflagellate Ostreopsis ovata Fukuyo have recently occurred along the whole Italian coastlines, both Tyrrhenian and Adriatic,…”
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9
Potent antioxidant and genoprotective effects of boeravinone G, a rotenoid isolated from Boerhaavia diffusa
Published in PloS one (20-05-2011)“…Free radicals are implicated in the aetiology of some gastrointestinal disorders such as gastric ulcer, colorectal cancer and inflammatory bowel disease. In…”
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10
Bromopyrrole alkaloids as lead compounds against protozoan parasites
Published in Marine drugs (14-07-2010)“…In the present study, 13 bromopyrrole alkaloids, including the oroidin analogs hymenidin (2), dispacamide B (3) and dispacamide D (4), stevensine (5) and…”
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11
Toxin levels and profiles in microalgae from the north-Western Adriatic Sea--15 years of studies on cultured species
Published in Marine Drugs (01-01-2012)“…The Northern Adriatic Sea is the area of the Mediterranean Sea where eutrophication and episodes related to harmful algae have occurred most frequently since…”
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12
Palytoxin and an Ostreopsis toxin extract increase the levels of mRNAs encoding inflammation-related proteins in human macrophages via p38 MAPK and NF-κB
Published in PloS one (01-06-2012)“…Palytoxin and, likely, its analogues produced by the dinoflagellate genus Ostreopsis, represent a class of non-proteinaceous compounds displaying high toxicity…”
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13
Evaluation of the Antiproliferative Activity of Diterpene Isonitriles from the Sponge Pseudoaxinella flava in Apoptosis-Sensitive and Apoptosis-Resistant Cancer Cell Lines
Published in Journal of natural products (Washington, D.C.) (28-10-2011)“…One new (1) and three known (2–4) isonitrile diterpenes, isolated from the Caribbean sponge Pseudoaxinella flava, were assayed in human cancer cell lines in…”
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14
Chloroscabrolides, chlorinated norcembranoids from the Indonesian soft coral Sinularia sp
Published in Tetrahedron (14-10-2011)“…Chemical analysis of the Indonesian soft coral Sinularia sp. (order Alcyonacea, family Alcyoniidae) afforded two known and three new C-4 norcembranoids, named…”
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Manadoperoxides A−D from the Indonesian Sponge Plakortis cfr. simplex. Further Insights on the Structure−Activity Relationships of Simple 1,2-Dioxane Antimalarials
Published in Journal of natural products (Washington, D.C.) (25-06-2010)“…The new endoperoxyketal polyketides manadoperoxides A−D (2−5) have been isolated from the Indonesian sponge Plakortis cfr. simplex and their stereostructures…”
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16
Chemical Composition of Shallot (Allium ascalonicum Hort.)
Published in Journal of agricultural and food chemistry (25-09-2002)“…An extensive phytochemical analysis of the polar extracts from bulbs of shallot, Allium ascalonicum Hort., led to the isolation of two new furostanol saponins,…”
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17
Further investigation of the Mediterranean sponge Axinella polypoides: isolation of a new cyclonucleoside and a new betaine
Published in Marine drugs (09-11-2012)“…An exhaustive exploration into the metabolic content of the Mediterranean sponge Axinella-polypoides resulted in the isolation of the new betaine 5 and the new…”
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18
Novel bioactive bromopyrrole alkaloids from the Mediterranean sponge Axinella verrucosa
Published in Bioorganic & medicinal chemistry (2006)“…The Mediterranean sponge Axinella verrucosa has been investigated for its alkaloid composition and has been found to produce a complex mixture of bromopyrrole…”
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19
Artarborol, a nor-Caryophyllane Sesquiterpene Alcohol from Artemisia arborescens . Stereostructure Assignment through Concurrence of NMR Data and Computational Analysis
Published in Organic letters (07-06-2007)“…A nor-caryophyllane derivative, artarborol, has been isolated from wormwood (Artemisia arborescens) and its stereostructure established by using a combination…”
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20
Amphiceramide A and B, Novel Glycosphingolipids from the Marine Sponge Amphimedon compressa
Published in European Journal of Organic Chemistry (01-05-2009)“…Glycolipid analysis of the Caribbean sponge Amphimedon compressa has shown it to contain two novel glycosphingolipids, amphiceramide A (1a) and B (2a), which…”
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