Search Results - "FASOLA, Gianpiero"

Measures of Outcome in Metastatic Breast Cancer: Insights From a Real‐World Scenario by Bonotto, Marta, Gerratana, Lorenzo, Poletto, Elena, Driol, Pamela, Giangreco, Manuela, Russo, Stefania, Minisini, Alessandro M., Andreetta, Claudia, Mansutti, Mauro, Pisa, Federica E., Fasola, Gianpiero, Puglisi, Fabio

“…No gold standard treatment exists for metastatic breast cancer (MBC). Clinical decision making is based on knowledge of prognostic and predictive factors that…”
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Immunotherapy in NSCLC Patients with Brain Metastases by Buriolla, Silvia, Pelizzari, Giacomo, Corvaja, Carla, Alberti, Martina, Targato, Giada, Bortolot, Martina, Torresan, Sara, Cortiula, Francesco, Fasola, Gianpiero, Follador, Alessandro

“…Approximately 40% of unselected non-small cell lung cancer (NSCLC) patients develop brain metastases (BMs) during their disease, with considerable morbidity…”
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Drug waste minimization as an effective strategy of cost-containment in oncology by Fasola, Gianpiero, Aprile, Giuseppe, Marini, Luisa, Follador, Alessandro, Mansutti, Mauro, Miscoria, Manuela

“…Sustainability of cancer care is a crucial issue for health care systems worldwide, even more during a time of economic recession. Low-cost measures are highly…”
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Detection of SARS-CoV-2 infection prevalence in 860 cancer patients with a combined screening procedure including triage, molecular nasopharyngeal swabs and rapid serological test. A report from the first epidemic wave by Candoni, Anna, Petruzzellis, Giuseppe, Sperotto, Alessandra, Andreotti, Victoria, Giavarra, Marco, Corvaja, Carla, Minisini, Alessandro, Comuzzi, Chiara, Tascini, Carlo, Fanin, Renato, Fasola, Gianpiero

“…Even if now we have available the weapon of vaccination against SARS-CoV-2, the patients with cancer remains a very frail population in which frequently the…”
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First- and second-line treatment strategies for hormone-receptor (HR)-positive HER2-negative metastatic breast cancer: A real-world study by Basile, Debora, Gerratana, Lorenzo, Corvaja, Carla, Pelizzari, Giacomo, Franceschin, Giorgia, Bertoli, Elisa, Palmero, Lorenza, Zara, Diego, Alberti, Martina, Buriolla, Silvia, Da Ros, Lucia, Bonotto, Marta, Mansutti, Mauro, Spazzapan, Simon, Cinausero, Marika, Minisini, Alessandro Marco, Fasola, Gianpiero, Puglisi, Fabio

“…Endocrine therapy (ET) plus cyclin-dependent-kinases 4/6 inhibitors (CDK4/6i) represents the standard treatment for luminal-metastatic breast cancer (MBC)…”
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The IMPACT study: early loss of skeletal muscle mass in advanced pancreatic cancer patients by Basile, Debora, Parnofiello, Annamaria, Vitale, Maria Grazia, Cortiula, Francesco, Gerratana, Lorenzo, Fanotto, Valentina, Lisanti, Camilla, Pelizzari, Giacomo, Ongaro, Elena, Bartoletti, Michele, Garattini, Silvio Ken, Andreotti, Victoria Josephine, Bacco, Anna, Iacono, Donatella, Bonotto, Marta, Casagrande, Mariaelena, Ermacora, Paola, Puglisi, Fabio, Pella, Nicoletta, Fasola, Gianpiero, Aprile, Giuseppe, Cardellino, Giovanni G.

“…Background Pancreatic cancer (PC) patients have multiple risk factors for sarcopenia and loss of skeletal muscle mass (LSMM), which may cause greater treatment…”
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Multidisciplinary Approach to Patients With Metastatic Spinal Cord Compression: A Diagnostic Therapeutic Algorithm to Improve the Neurological Outcome by Rispoli, Rossella, Reverberi, Chiara, Targato, Giada, D’Agostini, Serena, Fasola, Gianpiero, Trovò, Marco, Calci, Mario, Fanin, Renato, Cappelletto, Barbara

“…IntroductionThe morbidity associated with metastatic spinal disease is significant because of spinal cord and/or nerve root compression. The purpose of this…”
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Multidisciplinary management of immunotherapy‐related adverse events in solid tumors: An inter‐institutional and telemedicine‐based working team by Iaculli, Alessandro, Ghidini, Michele, Locati, Francesco, Chiappa, Laura, Nastasi, Giuseppe, Fasola, Gianpiero, Grossi, Francesco, Garrone, Ornella, Tozzi, Valeria D.

“…Background Although immune checkpoint inhibitors (ICIs) show a more favorable toxicity profile than classical cytotoxic drugs, their mechanism of action is…”
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Anti-tumor activity of all-trans retinoic acid in gastric-cancer: gene-networks and molecular mechanisms by Guarrera, Luca, Kurosaki, Mami, Garattini, Silvio-Ken, Gianni', Maurizio, Fasola, Gianpiero, Rossit, Luca, Prisciandaro, Michele, Di Bartolomeo, Maria, Bolis, Marco, Rizzo, Paola, Nastasi, Claudia, Foglia, Marika, Zanetti, Adriana, Paroni, Gabriela, Terao, Mineko, Garattini, Enrico

“…Background Gastric-cancer is a heterogeneous type of neoplastic disease and it lacks appropriate therapeutic options. There is an urgent need for the…”
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Clinico-pathological nomogram for predicting BRAF mutational status of metastatic colorectal cancer by Loupakis, Fotios, Moretto, Roberto, Aprile, Giuseppe, Muntoni, Marta, Cremolini, Chiara, Iacono, Donatella, Casagrande, Mariaelena, Ferrari, Laura, Salvatore, Lisa, Schirripa, Marta, Rossini, Daniele, De Maglio, Giovanna, Fasola, Gianpiero, Calvetti, Lorenzo, Pilotto, Sara, Carbognin, Luisa, Fontanini, Gabriella, Tortora, Giampaolo, Falcone, Alfredo, Sperduti, Isabella, Bria, Emilio

“…Background: In metastatic colorectal cancer (mCRC), BRAFV600E mutation has been variously associated to specific clinico-pathological features. Methods: Two…”
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KRAS and ERBB-family genetic alterations affect response to PD-1 inhibitors in metastatic nonsquamous NSCLC by Cinausero, Marika, Laprovitera, Noemi, Maglio, Giovanna De, Gerratana, Lorenzo, Riefolo, Mattia, Macerelli, Marianna, Fiorentino, Michelangelo, Porcellini, Elisa, Buoro, Vanessa, Gelsomino, Francesco, Squadrilli, Anna, Fasola, Gianpiero, Negrini, Massimo, Tiseo, Marcello, Ferracin, Manuela, Ardizzoni, Andrea

“…Background: Programmed cell death 1 (PD-1) and PD-ligand 1 (PD-L1) inhibitors represent novel therapeutic options for advanced non-small cell lung cancer…”
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CDK4/6 Inhibitors as Upfront Treatment in a Patient with Breast Cancer Presenting with a Clinical Critic Situation: A Case Report and Review of the Literature by Targato, Giada, Bortot, Lucia, Dri, Arianna, Bonotto, Marta, Minisini, Alessandro Marco, Fasola, Gianpiero, Mansutti, Mauro

“…CDK4/6 inhibitors have revolutionized the treatment algorithm of luminal metastatic breast cancer, becoming the recommended first-line therapy in association…”
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Biologically driven cut-off definition of lymphocyte ratios in metastatic breast cancer and association with exosomal subpopulations and prognosis by Gerratana, Lorenzo, Basile, Debora, Toffoletto, Barbara, Bulfoni, Michela, Zago, Silvia, Magini, Alessandro, Lera, Marta, Pelizzari, Giacomo, Parisse, Pietro, Casalis, Loredana, Vitale, Maria Grazia, Fanotto, Valentina, Bonotto, Marta, Caponnetto, Federica, Bartoletti, Michele, Lisanti, Camilla, Minisini, Alessandro Marco, Emiliani, Carla, Di Loreto, Carla, Fasola, Gianpiero, Curcio, Francesco, Beltrami, Antonio Paolo, Cesselli, Daniela, Puglisi, Fabio

“…High neutrophil to lymphocyte ratio (NLR) and monocyte to lymphocyte ratio (MLR) are respectively associated with systemic inflammation and immune suppression…”
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Validated clinico-pathologic nomogram in the prediction of HER2 status in gastro-oesophageal cancer by Fornaro, Lorenzo, Vivaldi, Caterina, Parnofiello, Annamaria, Ugolini, Clara, Aprile, Giuseppe, De Maglio, Giovanna, Pecora, Irene, Iacono, Donatella, Crivelli, Francesca, Catanese, Silvia, Cardellino, Giovanni Gerardo, Lencioni, Monica, Vasile, Enrico, Salani, Francesca, Clerico, Mario, Calvetti, Lorenzo, Falcone, Alfredo, Fasola, Gianpiero, Fontanini, Gabriella, Montagnani, Francesco

“…Background HER2 is the only validated predictive biomarker in gastro-oesophageal carcinoma (GOC). However, several factors, such as heterogeneity in protein…”
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Rare and Insidious Toxicities from New Combination Therapies in Metastatic Renal Cell Cancer: Lessons Learned from Real-Practice by Dri, Arianna, Garattini, Silvio Ken, Cinausero, Marika, Macerelli, Marianna, Fanelli, Martina, Puglisi, Fabio, Fasola, Gianpiero, Ermacora, Paola

“…The advent of immune checkpoint inhibitors in combination with multitarget tyrosine kinase inhibitors has become a standard first-line treatment for metastatic…”
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Multidisciplinary Team Meeting Proposal and Final Therapeutic Choice in Early Breast Cancer: Is There an Agreement? by Bortot, Lucia, Targato, Giada, Noto, Claudia, Giavarra, Marco, Palmero, Lorenza, Zara, Diego, Bertoli, Elisa, Dri, Arianna, Andreetta, Claudia, Pascoletti, Gaetano, Poletto, Elena, Russo, Stefania, Seriau, Luca, Mansutti, Mauro, Cedolini, Carla, Basile, Debora, Fasola, Gianpiero, Bonotto, Marta, Minisini, Alessandro Marco

“…A multidisciplinary team meeting (MDM) approach in breast cancer (BC) management is a standard of care. One of the roles of MDMs is to identify the best…”
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Impact of Third‐Generation Drugs on the Activity of First‐Line Chemotherapy in Advanced Non‐Small Cell Lung Cancer: A Meta‐Analytical Approach by Grossi, Francesco, Aita, Marianna, Defferrari, Carlotta, Rosetti, Francesco, Brianti, Annalisa, Fasola, Gianpiero, Vinante, Orazio, Pronzato, Paolo, Pappagallo, Giovanni

“…Background. The therapeutic equivalence of different third‐generation agents in the first‐line treatment of advanced non‐small cell lung cancer (NSCLC) has…”
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Small-Cell Lung Cancer: Clinical Management and Unmet Needs New Perspectives for an Old Problem by Lo Russo, Giuseppe, Macerelli, Marianna, Platania, Marco, Zilembo, Nicoletta, Vitali, Milena, Signorelli, Diego, Proto, Claudia, Ganzinelli, Monica, Gallucci, Rosaria, Agustoni, Francesco, Fasola, Gianpiero, de Braud, Filippo, Garassino, Marina Chiara

“…Small cell lung cancer is a highly aggressive, difficult to treat neoplasm. Among all lung tumors, small cell lung cancers account for about 20%. Patients…”
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Molecular classifications of gastric cancers: Novel insights and possible future applications by Garattini, Silvio Ken, Basile, Debora, Cattaneo, Monica, Fanotto, Valentina, Ongaro, Elena, Bonotto, Marta, Negri, Francesca V, Berenato, Rosa, Ermacora, Paola, Cardellino, Giovanni Gerardo, Giovannoni, Mariella, Pella, Nicoletta, Scartozzi, Mario, Antonuzzo, Lorenzo, Silvestris, Nicola, Fasola, Gianpiero, Aprile, Giuseppe

“…Despite some notable advances in the systemic management of gastric cancer(GC), the prognosis of patients with advanced disease remains overall poor and their…”
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Phase II randomized study of vandetanib plus gemcitabine or gemcitabine plus placebo as first-line treatment of advanced non-small-cell lung cancer in elderly patients by Gridelli, Cesare, Novello, Silvia, Zilembo, Nicoletta, Luciani, Andrea, Favaretto, Adolfo Gino, De Marinis, Filippo, Genestreti, Giovenzio, Crinò, Lucio, Grossi, Francesco, Caffo, Orazio, Ferraù, Francesco, Cruciani, Giorgio, Brandes, Alba Ariela, Galetta, Domenico, Barni, Sandro, Fasola, Gianpiero, Cerea, Giulio, Ferrari, Silvia, Iannacone, Claudio, Ciardiello, Fortunato

“…The aim of the present study was to evaluate the efficacy and tolerability of vandetanib plus gemcitabine (V/G) compared with gemcitabine alone in elderly…”
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