Anthelmintic treatment follow up in a rural community in Camamu, Bahia, Brazil

Enteroparasites are an important public health problem and the treatment seeks to cure and reduce transmission. The aim of this study was to evaluate the therapeutic efficacy of anthelmintic treatment in individuals living in a rural community area in Camamu, Bahia, Brazil. The parasitological diagn...

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Published in:	Anais da Academia Brasileira de Ciências Vol. 95; no. 3; p. e20230323
Main Authors:	FARIAS, MARINA M.B., BARRETO, NILO MANOEL P.V., ARAÚJO, WESLEI A.C., OLIVEIRA, CÍNTIA DE LIMA, GONÇALVES, NOILSON LÁZARO S., CAMPAGNOLLO, KAMILA S.S., TEIXEIRA, MÁRCIA CRISTINA A., GALVÃO-CASTRO, BERNARDO, SOARES, NECI M., SOUZA, JOELMA N. DE
Format:	Journal Article
Language:	English
Published:	Academia Brasileira de Ciências 01-01-2023
Subjects:	Diagnosis Enteroparasites Follow-up MULTIDISCIPLINARY SCIENCES Treatment Treatment Diagnosis Enteroparasites Follow-up
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Summary:	Enteroparasites are an important public health problem and the treatment seeks to cure and reduce transmission. The aim of this study was to evaluate the therapeutic efficacy of anthelmintic treatment in individuals living in a rural community area in Camamu, Bahia, Brazil. The parasitological diagnosis was performed by spontaneous sedimentation, Baermann-Moraes and Agar Plate Culture methods. A total of 212 individuals were evaluated. The most frequent helminth was Trichuris trichiura, 24.5% (52/212), followed by Ascaris lumbricoides, 21.2% (45/212), hookworms, 16.5% (35/212), and S. stercoralis, 4.7% (10/212). In the anthelmintic treatment follow up, T. trichiura infection presented the lowest parasitological cure rate, only 60.6% (20/33). Hookworm, Ascaris lumbricoides and Strongyloides stercoralis infections demonstrated cure rates of 70.5 (12/17), 78.1 (25/32) and 100% (5/5), respectively. Individuals who remained infected underwent a new drug therapy. The second parasitological cure rate for T. trichiura was 38.5% (5/13), and 66.7% (2/3) and 75% (3/4) for hookworms and Ascaris lumbricoides, respectively. Trichuris trichiura infection presented the lowest parasitological cure rate at this second evaluation. This reinforces the need to perform a follow-up of all treated individuals. The possibility of drug resistance denotes the necessity for studies to clarify the mechanisms and to evaluate new therapeutic approaches.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0001-3765 1678-2690 1678-2690
DOI:	10.1590/0001-3765202320230323