Search Results - "FARFEL, José Marcelo"
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Equal numbers of neuronal and nonneuronal cells make the human brain an isometrically scaled-up primate brain
Published in Journal of comparative neurology (1911) (10-04-2009)“…The human brain is often considered to be the most cognitively capable among mammalian brains and to be much larger than expected for a mammal of our body…”
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Association between health literacy and glycemic control in elderly patients with type 2 diabetes and modifying effect of social support
Published in Einstein (São Paulo, Brazil) (01-01-2020)“…To investigate the association between inadequate functional health literacy, considering the Short Assessment of Health Literacy for Portuguese-speaking…”
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3
Estimating premorbid cognitive abilities in low-educated populations
Published in PloS one (21-03-2013)“…To develop an informant-based instrument that would provide a valid estimate of premorbid cognitive abilities in low-educated populations. A questionnaire was…”
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Olfaction in Neurologic and Neurodegenerative Diseases: A Literature Review
Published in International Archives of Otorhinolaryngology (01-04-2015)“…Abstract Introduction Loss of smell is involved in various neurologic and neurodegenerative diseases, such as Parkinson disease and Alzheimer disease…”
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Validity of the Katz Index to assess activities of daily living by informants in neuropathological studies
Published in Revista da Escola de Enfermagem da U S P (01-12-2015)“…To analyze the evidences of construct validity of the Katz Index for the retrospective assessment of activities of daily living (ADL) by informants, to assist…”
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Applicability of the Spoken Knowledge in Low Literacy Patients with Diabetes in Brazilian elderly
Published in Einstein (São Paulo, Brazil) (01-10-2016)“…To translate, adapt and evaluate the properties of a Brazilian Portuguese version of the Spoken Knowledge in Low Literacy Patients with Diabetes, which is a…”
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Association between adiposity and systemic atherosclerosis: a protocol of a cross-sectional autopsy study
Published in Open heart (01-08-2016)“…IntroductionAdiposity has been associated with atherosclerosis in clinical studies. However, few autopsy studies have investigated this association, and they…”
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Argyrophilic Grain Disease: Demographics, Clinical, and Neuropathological Features From a Large Autopsy Study
Published in Journal of neuropathology and experimental neurology (01-07-2016)“…Argyrophilic grain disease (AGD) is a frequent late-onset, 4-repeat tauopathy reported in Caucasians with high educational attainment. Little is known about…”
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Vascular Risk as a Predictor of Cognitive Decline in a Cohort of Elderly Patients with Mild to Moderate Dementia
Published in Dementia and geriatric cognitive disorders extra (29-10-2014)“…Background/Aims: The purpose of our study was to evaluate vascular risk factors and other clinical variables as predictors of cognitive and functional decline…”
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10
DNA methylation of the promoter region at the CREB1 binding site is a mechanism for the epigenetic regulation of brain-specific PKMζ
Published in Biochimica et biophysica acta. Gene regulatory mechanisms (01-03-2023)“…Protein kinase M zeta, PKMζ, is a brain enriched kinase with a well characterized role in Long-Term Potentiation (LTP), the activity-dependent strengthening of…”
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Layer-specific reduced neuronal density in the orbitofrontal cortex of older adults with obsessive–compulsive disorder
Published in Brain Structure and Function (01-01-2019)“…Neurobiological models have provided consistent evidence of the involvement of cortical–subcortical circuitry in obsessive–compulsive disorder (OCD). The…”
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Complex Network-Driven View of Genomic Mechanisms Underlying Parkinson’s Disease: Analyses in Dorsal Motor Vagal Nucleus, Locus Coeruleus, and Substantia Nigra
Published in BioMed research international (01-01-2014)“…Parkinson’s disease (PD)—classically characterized by severe loss of dopaminergic neurons in the substantia nigra pars compacta—has a caudal-rostral…”
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Is Olfactory Epithelium Biopsy Useful for Confirming Alzheimer’s Disease?
Published in Annals of otology, rhinology & laryngology (01-03-2019)“…Objectives: The clinical symptoms of Alzheimer’s disease (AD) are preceded by a long asymptomatic period associated with “silent” deposition of aberrant paired…”
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Adverse drug events leading to emergency department visits in elderly: the role of inappropriate prescription
Published in Einstein (São Paulo, Brazil) (01-06-2010)“…Adverse drug reactions are more incident among the elderly and are frequently associated to inappropriate prescription for this group. The objective of the…”
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Brain bank of the Brazilian aging brain study group- : a milestone reached and more than 1,600 collected brains
Published in Cell and tissue banking (01-06-2007)“…Brain banking remains a necessity for the study of aging brain processes and related neurodegenerative diseases. In the present paper, we report the methods…”
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Depression and cardiovascular risk factors: evidence from a large postmortem sample
Published in International journal of geriatric psychiatry (01-05-2013)“…Objectives We aimed to investigate the association of depression with cardiovascular risk factors and diseases (CVRFD) in a large population‐based sample…”
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Factors associated with morphometric brain changes in cognitively normal aging
Published in Dementia & neuropsychologia (01-06-2015)“…Cognitive impairment is associated with reductions in brain weight and volume. The factors related to morphometric brain changes in cognitively normal aging…”
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Initial findings of striatum tripartite model in OCD brain samples based on transcriptome analysis
Published in Scientific reports (28-02-2019)“…Obsessive-compulsive disorder (OCD) is a psychiatric disorder characterized by obsessions and/or compulsions. Different striatal subregions belonging to the…”
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Higher Prevalence of TDP-43 Proteinopathy in Cognitively Normal Asians: A Clinicopathological Study on a Multiethnic Sample
Published in Brain pathology (Zurich, Switzerland) (01-03-2016)“…Transactive response DNA binding protein 43 (TDP‐43) proteinopathy is the major hallmark of frontotemporal lobar degeneration and amyotrophic lateral…”
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Factors related to the occurrence of iatrogenesis in elderly patients hospitalized in a geriatric ward: a prospective study
Published in Einstein (São Paulo, Brazil) (01-09-2008)“…Objective: The proliferation of drugs, therapeutic and diagnostic procedures in the modern medical practice leads to an increased incidence of iatrogenesis…”
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