Search Results - "FARAH, CLAUDE S."
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Mepolizumab effectiveness and identification of super-responders in severe asthma
Published in The European respiratory journal (01-05-2020)“…Severe asthma is a high-burden disease. Real-world data on mepolizumab in patients with severe eosinophilic asthma is needed to assess whether the data from…”
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Clinical significance and applications of oscillometry
Published in European respiratory review (31-03-2022)“…Recently, "Technical standards for respiratory oscillometry" was published, which reviewed the physiological basis of oscillometric measures and detailed the…”
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Asthma and obesity: A known association but unknown mechanism
Published in Respirology (Carlton, Vic.) (01-04-2012)“…ABSTRACT The obese asthma phenotype is an increasingly common encounter in our clinical practice. Epidemiological data indicate that obesity increases the…”
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The role of the small airways in the clinical expression of asthma in adults
Published in Journal of allergy and clinical immunology (01-02-2012)“…Background The clinical relevance of increased ventilation heterogeneity, a marker of small-airways disease, in asthmatic patients is unclear. Ventilation…”
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Day-to-day variability of forced oscillatory mechanics for early detection of acute exacerbations in COPD
Published in The European respiratory journal (01-09-2020)“…Telemonitoring trials for early detection of acute exacerbations of chronic obstructive pulmonary disease (AECOPD) have provided mixed results. Day-to-day…”
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Reduced lung elastic recoil and fixed airflow obstruction in asthma
Published in Respirology (Carlton, Vic.) (01-06-2020)“…ABSTRACT Background and objective Fixed airflow obstruction (FAO) in asthma occurs despite optimal inhaled treatment and no smoking history, and remains a…”
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Ventilation heterogeneity predicts asthma control in adults following inhaled corticosteroid dose titration
Published in Journal of allergy and clinical immunology (01-07-2012)“…Background Asthma guidelines recommend inhaled corticosteroid (ICS) dose titration for patients on the basis of an assessment of current asthma control…”
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Exercise-Induced Bronchoconstriction Identified Using the Forced Oscillation Technique
Published in Frontiers in physiology (15-11-2019)“…Objective: Lung mechanics using the forced oscillation technique (FOT) is suggested to be equivalent and more sensitive in determining exercise-induced…”
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Obesity Is a Determinant of Asthma Control Independent of Inflammation and Lung Mechanics
Published in Chest (01-09-2011)“…Background It is unclear why obesity is associated with worse asthma control. We hypothesized that (1) obesity affects asthma control independent of…”
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An example of ventilatory limitation during cardiopulmonary exercise testing in a patient with COPD
Published in Respirology case reports (01-05-2024)“…A 64‐year‐old obese gentleman attended for further evaluation of ongoing dyspnoea in the context of a previous diagnosis of moderate COPD treated with dual…”
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Mechanisms of gas transfer impairment utilizing nitric oxide following severe COVID‐19 pneumonitis
Published in Physiological reports (01-04-2023)“…Reduced carbon monoxide diffusing capacity (DLCO) is common after recovery from severe COVID‐19 pneumonitis. The extent to which this relates to alveolar…”
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Quality assessment pathway for respiratory oscillometry
Published in ERJ open research (01-01-2022)“…https://bit.ly/3G4r0X1…”
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Obesity, expiratory flow limitation and asthma symptoms
Published in Pulmonary pharmacology & therapeutics (01-08-2013)“…Abstract Obesity is associated with poor asthma control, but the reason for this is unclear. Reduction in operating lung volume, as occurs in obesity, and…”
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Preventing adverse cardiac events (PACE) in chronic obstructive pulmonary disease (COPD): study protocol for a double-blind, placebo controlled, randomised controlled trial of bisoprolol in COPD
Published in BMJ open (27-08-2021)“…IntroductionHeart disease in chronic obstructive pulmonary disease (COPD) is a common but neglected comorbidity. Patients with COPD are frequently excluded…”
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Within-session variability as quality control for oscillometry in health and disease
Published in ERJ open research (01-10-2021)“…Oscillometry is increasingly adopted in respiratory clinics, but many recommendations regarding measurement settings and quality control remain subjective. The…”
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Predictors of Airway Hyperresponsiveness Differ Between Old and Young Patients With Asthma
Published in Chest (01-06-2011)“…Background Age-related increases in morbidity and mortality due to asthma may be due to changes in pathophysiology as patients with asthma get older. There is…”
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Normal limits for oscillometric bronchodilator responses and relationships with clinical factors
Published in ERJ open research (01-10-2021)“…We aimed to determine normal thresholds for positive bronchodilator responses for oscillometry in an Australian general population sample aged ≥40 years, to…”
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Assessment of Airway Distensibility by the Forced Oscillation Technique: Reproducible and Potentially Simplifiable
Published in Frontiers in physiology (12-04-2017)“…A non-invasive index of airway distensibility is required to track airway remodeling over time. The forced oscillation technique (FOT) provides such an index…”
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Airways wide shut: A physiological phenotype of asthma?
Published in Respirology (Carlton, Vic.) (01-07-2019)“…See related Article See related Article…”
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Bronchodilator Response Assessed by the Forced Oscillation Technique Identifies Poor Asthma Control With Greater Sensitivity Than Spirometry
Published in Chest (01-06-2020)“…Persistent bronchodilator response (BDR) following diagnosis of asthma is an underrecognized treatable trait, associated with worse lung function and asthma…”
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