Search Results - "FALLET, Vincent"
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Lung cancer is also a hereditary disease
Published in European respiratory review (31-12-2021)“…Pathogenic genetic variants (formerly called mutations) present in the germline of some individuals are associated with a clinically relevant increased risk of…”
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Sarcomatoid lung carcinomas show high levels of Programmed Death Ligand-1 (PD-L1) and strong immune-cell infiltration by TCD3 cells and macrophages
Published in Lung cancer (Amsterdam, Netherlands) (01-08-2016)“…Highlights • PD-L1, tumor-infiltrating lymphocytes (TIL) were higher in SC than in NSCLC. • High levels of TIL constituted a factor of good prognosis. • PD-L1…”
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Pulmonary complications of immune checkpoint inhibitors in patients with nonsmall cell lung cancer
Published in European respiratory review (30-09-2019)“…Immune checkpoint inhibitor-related pneumonitis (ICI-P) during cancer treatment is rarely observed (<5%). ICI-P is more often observed in patients with…”
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Mpox Hepatic and Pulmonary Lesions in HIV/Hepatitis B Virus Co-Infected Patient, France
Published in Emerging infectious diseases (01-11-2024)“…We report a case of persistent disseminated mpox evolving over >6 months in an HIV/hepatitis B virus co-infected patient in France who had <200 CD4+ cells/mm ,…”
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Dramatic Radiation Recall Pneumonitis Induced by Osimertinib after Palliative Thoracic Radiotherapy for Lung Cancer
Published in Journal of thoracic oncology (01-10-2019)Get more information
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Therapeutic strategies to overcome EGFR mutations as acquired resistance mechanism in ALK-rearranged non-small-cell lung cancer: Case Reports
Published in Frontiers in oncology (28-06-2023)“…ALK tyrosine kinase inhibitors (ALK TKIs) have improved prognosis in -rearranged ( ) non-small-cell lung cancer (NSCLC). However, drug resistance mechanisms…”
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Blood vessel invasion is a major feature and a factor of poor prognosis in sarcomatoid carcinoma of the lung
Published in Lung cancer (Amsterdam, Netherlands) (01-08-2014)“…Highlights • A dedifferentiation process in NSCLC could lead to sarcomatoid carcinoma (SC). • NSCLC and SC share morphological, immunohistochemical and…”
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MET exon 14 mutations as targets in routine molecular analysis of primary sarcomatoid carcinoma of the lung
Published in Oncotarget (27-06-2017)“…MET exon 14 splicing mutations are new targetable oncogenic drivers reported in 3% of non-small cell lung cancer (NSCLC) cases and have been shown to be more…”
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Exposure-Response Analysis of Osimertinib in Patients with Advanced Non-Small-Cell Lung Cancer
Published in Pharmaceutics (01-09-2022)“…High interindividual variability (IIV) of the clinical response to epidermal growth factor receptor (EGFR) inhibitors such as osimertinib in non-small-cell…”
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Prospective screening for ALK : Clinical features and outcome according to ALK status
Published in European journal of cancer (1990) (01-05-2014)“…Abstract The aim of this study was to analyse the clinico-pathological characteristics and outcomes of a cohort of French patients who were prospectively…”
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Anti-PD-1 immune-related adverse events are associated with high therapeutic antibody fixation on T cells
Published in Frontiers in immunology (20-12-2022)“…Immune checkpoint inhibitors (ICI) widely improved the treatment of solid and hematologic malignancies. Yet, a remarkable proportion of patients receiving ICI…”
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Efficacy of next treatment received after nivolumab progression in patients with advanced nonsmall cell lung cancer
Published in ERJ open research (01-04-2018)“…Nivolumab for the treatment of advanced nonsmall cell lung cancer (NSCLC) evaluated in phase III trials showed 50% progression at first evaluation, but better…”
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Percutaneous Image-Guided Electrochemotherapy of Spine Metastases: Initial Experience
Published in Cardiovascular and interventional radiology (01-12-2019)Get full text
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Secondary resistance to erlotinib: acquired T790M mutation and small-cell lung cancer transformation in the same patient
Published in Journal of thoracic oncology (01-06-2012)Get more information
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Emerging cancer risks in BRCA2 pathogenic germline variant carriers
Published in European journal of human genetics : EJHG (01-12-2023)Get full text
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Do Female BRCA2 Pathogenic Variant Carriers Have an Increased Risk of Lung Cancer?
Published in Journal of clinical oncology (01-08-2022)Get full text
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Pralsetinib and Sequential MET Inhibitors to Overcome MET Amplification Resistance in a Patient With a RET Fusion Driven Lung Cancer – Case Report
Published in Clinical lung cancer (01-12-2022)“…What is already known about this subject?•Rearranged during transfection (RET) gene fusion are unfrequent (1%-2%) but validated as target mutations in…”
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Multimodal machine learning model prediction of “individual” response to immunotherapy in 1L stage IV NSCLC
Published in Journal of clinical oncology (01-06-2022)“…e21151 Background: Immunotherapy (IO) is the standard of care in 1L stage IV non-small cell lung cancer (NSCLC) cases that are not eligible for targeted…”
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Circulating tumour cells as a potential biomarker for lung cancer screening: a prospective cohort study
Published in The lancet respiratory medicine (01-07-2020)“…Lung cancer screening with low-dose chest CT (LDCT) reduces the mortality of eligible individuals. Blood signatures might act as a standalone screening tool,…”
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Invited editorial: Q and A on hereditary lung cancer
Published in Respiratory medicine and research (01-05-2022)“…Advances in the field of genetic susceptibility to respiratory diseases (e.g. pulmonary fibrosis, emphysema, cystic fibrosis, pulmonary hypertension) have led…”
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