Search Results - "FAIR, D. S"

Local abnormalities in coagulation and fibrinolytic pathways predispose to alveolar fibrin deposition in the adult respiratory distress syndrome by IDELL, S, JAMES, K. K, LEVIN, E. G, SCHWARTZ, B. S, MANCHANDA, N, MAUNDER, R. J, MARTIN, T. R, MCLARTY, J, FAIR, D. S

“…To determine the possible mechanism(s) promoting alveolar fibrin deposition in the adult respiratory distress syndrome (ARDS), we investigated the initiation…”
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Serial abnormalities of fibrin turnover in evolving adult respiratory distress syndrome by Idell, S, Koenig, K B, Fair, D S, Martin, T R, McLarty, J, Maunder, R J

“…We studied the changes of coagulation and fibrinolysis in bronchoalveolar lavage (BAL) and plasma obtained serially at intervals after the onset of adult…”
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Quantitation of Factor VII in the Plasma of Normal and Warfarin-Treated Individuals by Radioimmunoassay by Fair, Daryl S.

“…Highly purified single-chain factor VII was isolated from plasma and used to generate monospecific antibodies. A double-antibody equilibrium radioimmunoassay…”
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Biosynthesis and Secretion of Factor VII, Protein C, Protein S, and the Protein C Inhibitor From a Human Hepatoma Cell Line by Fair, Daryl S., Marlar, Richard A.

“…Using specific radioimmunoassays, 8 day cultures of Hep G2 cells were shown to contain in their supernatants 16, 74, and 828 ng/mL and in their cell lysates,…”
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Molecular recognition sites on factor Xa which participate in the prothrombinase complex by CHATTOPADHYAY, A, JAMES, H. L, FAIR, D. S

“…Coagulation factor X, when activated to factor Xa by proteolytic cleavage, itself becomes an active serine protease which participates as a component of the…”
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Human Endothelial Cells Synthesize Protein S by Fair, Daryl S., Marlar, Richard A., Levin, Eugene G.

“…Human umbilical vein endothelial cells were analyzed for the presence of prothrombin, factor VII, protein C, and protein S in culture supernatants and cell…”
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Cooperative interaction between factor VII and cell surface-expressed tissue factor by Fair, D S, MacDonald, M J

“…Assembly of the extrinsic pathway on cell surfaces was investigated by studying the binding and activity of factor VII on the bladder carcinoma cell line J82…”
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Molecular Defect in Coagulation Factor XFriuli Results From a Substitution of Serine for Proline at Position 343 by James, Harold L., Girolami, Antonio, Fair, Daryl S.

“…Our previous findings suggested that coagulation factor XmFriuli could be functionally defective owing to a point mutation in the portion of the factor X gene…”
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Local abnormalities of coagulation and fibrinolytic pathways that promote alveolar fibrin deposition in the lungs of baboons with diffuse alveolar damage by IDELL, S, PETERS, J, JAMES, K. K, FAIR, D. S, COALSON, J. J

“…Because alveolar fibrin is a prominent histologic feature of diffuse lung injury in baboons, we hypothesized that local abnormalities of pathways of fibrin…”
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Molecular Recognition in the Activation of Human Blood Coagulation Factor X by Chattopadhyay, A, Fair, D S

“…Factor X can be activated by the extrinsic activation complex (factor VIIa:tissue factor), the intrinsic activation complex (factor IXa:factor VIIIa) and by an…”
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Abnormalities of pathways of fibrin turnover in lung lavage of rats with oleic acid and bleomycin-induced lung injury support alveolar fibrin deposition by Idell, S, James, KK, Gillies, C, Fair, DS, Thrall, RS

“…Alveolar fibrin deposition commonly accompanies acute lung injury, but the nature of the local abnormalities of coagulation and fibrinolysis that support…”
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Hereditary Factor VII Deficiency: Heterogeneity Defined by Combined Functional and Immunochemical Analysis by Triplett, Douglas A., Brandt, John T., Batard, Mary Ann McGann, Dixon, Janis L. Schaeffer, Fair, Darvl S.

“…Twenty-six patients with hereditary factor VII deficiency (VII:C < 10%) were evaluated using a panel of three thromboplastins of varying species and tissue…”
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Monoclonal antibody analysis of purified and cell-associated tissue factor by Morrissey, J H, Fair, D S, Edgington, T S

“…Tissue factor (TF), one of the cell-surface initiators of blood coagulation, has been implicated as the major molecule of this type and as a critical…”
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Initiation of the extrinsic pathway of coagulation. Association of factor VIIa with a cell line expressing tissue factor by Ploplis, V A, Edgington, T S, Fair, D S

“…We have examined initial assembly of the extrinsic pathway of blood coagulation on cell surfaces with radiolabeled human factor VIIa and a human fetal lung…”
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Immunologic Relationship between Platelet Membrane Glycoprotein GPIIb/IIIa and Cell Surface Molecules Expressed by a Variety of Cells by Plow, Edward F., Loftus, Joseph C., Levin, Eugene G., Fair, Daryl S., Dixon, Douglas, Forsyth, Jane, Ginsberg, Mark H.

“…A polyclonal antiserum to platelet membrane glycoprotein GPIIb/IIIa was used to detect antigenically related molecules on a diverse panel of human cells…”
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Inhibition of factor Xa-mediated procoagulant activity of human lung fibroblasts and pleural mesothelial cells by Kumar, A, Koenig, KB, Johnson, AR, Fair, DS, Idell, S

“…Extravascular fibrin deposition characterizes diverse forms of lung and pleural injury. Fibrin formation in these compartments is locally potentiated by the…”
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Resolution of monomeric and heterodimeric forms of tissue factor, the high-affinity cellular receptor for factor VII by Morrissey, J H, Revak, D, Tejada, P, Fair, D S, Edgington, T S

“…Tissue factor (TF) is the high affinity cell surface receptor and obligatory cofactor for plasma coagulation factor VII. Purification of TF from human brain…”
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Identification of molecular sites on factor VII which mediate its assembly and function in the extrinsic pathway activation complex by Kumar, A, Blumenthal, D K, Fair, D S

“…Factor VII-VIIa, in association with tissue factor, participates in the complex which initiates blood coagulation through the extrinsic pathway. To identify…”
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Hereditary factor VII deficiency: heterogeneity defined by combined functional and immunochemical analysis by Triplett, DA, Brandt, JT, Batard, MA, Dixon, JL, Fair, DS

“…Twenty-six patients with hereditary factor VII deficiency (VII:C less than 10%) were evaluated using a panel of three thromboplastins of varying species and…”
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Human Hepatoma Cells Secrete Single Chain Factor X, Prothrombin, and Antithrombin III by Fair, Daryl S., Bahnak, Bruce R.

“…The human hepatoma cell line, Hep G2, was analyzed for the ability to synthesize and secrete several coagulation proteins. Using specific radioimmunoassays,…”
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