Search Results - "FADI XU"

An advanced recording and analysis system for the differentiation of guinea pig cough responses to citric acid and prostaglandin E2 in real time by Zhuang, Jianguo, Zhao, Lei, Gao, Xiuping, Xu, Fadi

“…Cough number and/or sound have been used to assess cough sensitivity/intensity and to discriminate cough patterns in clinical settings. However, to date, only…”
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Cross-effect of TRPV1 and EP3 receptor on coughs and bronchopulmonary C-neural activities by Gao, Xiuping, Zhuang, Jianguo, Zhao, Lei, Wei, Wan, Xu, Fadi

“…Prostaglandin E2 (PGE2)-induced coughs in vivo and vagal nerve depolarization in vitro are inhibited by systemic and local administration of prostaglandin EP3…”
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Apneic response to fentanyl in adult rats: Role of laryngeal afferents by Zhuang, Jianguo, Gao, Xiuping, Shi, Shan, Xu, Fadi

“…Intravenous (systemic) bolus injection of fentanyl (FNT) reportedly induces an immediate vagal-mediated apnea; however, the precise origin of vagal afferents…”
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Mu-Opioid Receptors in the Caudomedial NTS Are Critical for Respiratory Responses to stimulation of bronchopulmonary C-fibers and Carotid Body in Conscious Rats by Zhuang, Jianguo, Gao, Xiuping, Gao, Franklin, Xu, Fadi, MD

“…Highlights • The cmNTS presents the highest MORs in the caudal medulla. • Activation of cmNTS MORs blocks or almost eliminates the PCF-mediated apnea and HVR…”
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DT-0111: a novel drug-candidate for the treatment of COPD and chronic cough by Pelleg, Amir, Xu, Fadi, Zhuang, Jianguo, Undem, Bradley, Burnstock, Geoffrey

“…Background: Extracellular adenosine 5′-triphosphate (ATP) plays important mechanistic roles in pulmonary disorders in general and chronic obstructive pulmonary…”
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Highly Efficient Production of Cellulosic Ethanol from Poplar Using an Optimal C6/C5 Co-Fermentation Strain of Saccharomyces cerevisiae by Xu, Fadi, Sun, Dongming, Wang, Zhaojiang, Li, Menglei, Yin, Xiaolong, Li, Hongxing, Xu, Lili, Zhao, Jianzhi, Bao, Xiaoming

“…Cellulosic ethanol is the key technology to alleviate the pressure of energy supply and climate change. However, the ethanol production process, which is close…”
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Roles of Bronchopulmonary C-fibers in airway Hyperresponsiveness and airway remodeling induced by house dust mite by Yang, Zhimei, Zhuang, Jianguo, Zhao, Lei, Gao, Xiuping, Luo, Zhengxiu, Liu, Enmei, Xu, Fadi, Fu, Zhou

“…Asthma is characterized by chronic airway inflammation, airway hyperresponsiveness (AHR), and airway remodeling. While exposure of house dust mites (HDM) is a…”
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High-Efficient Production of Cellulosic Ethanol from Corn Fiber Based on the Suitable C5/C6 Co-Fermentation Saccharomyces cerevisiae Strain by Li, Menglei, Xu, Fadi, Zhao, Yuping, Sun, Dongming, Liu, Jiao, Yin, Xiaolong, Li, Zailu, Zhao, Jianzhi, Li, Hongxing, Bao, Xiaoming

“…As a potential alternative to fossil-based fuels, cellulosic ethanol has attracted much attention due to its great benefit to energy sustainability and…”
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Activation of opioid μ receptors in caudal medullary raphe region inhibits the ventilatory response to hypercapnia in anesthetized rats by Zhang, Zhenxiong, Xu, Fadi, Zhang, Cancan, Liang, Xiaomin

“…: Opioids, extensively used as analgesics, markedly depress ventilation, particularly the ventilatory responsiveness to hypercapnia in humans and animals…”
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Depressed Hypoxic and Hypercapnic Ventilatory Responses at Early Stage of Lethal Avian Influenza A Virus Infection in Mice by Zhuang, Jianguo, Gao, Peng, Pollock, Zemmie, Harrod, Kevin S, Xu, Fadi

“…H5N1 virus infection results in ~60% mortality in patients primarily due to respiratory failure, but the underlying causes of mortality are unclear. The goal…”
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Activation of Opioid μ-Receptors in the Commissural Subdivision of the Nucleus Tractus Solitarius Abolishes the Ventilatory Response to Hypoxia in Anesthetized Rats by Zhang, Zhenxiong, Zhuang, Jianguo, Zhang, Cancan, Xu, Fadi

“…: The commissural subnucleus of the nucleus tractus solitarius (comNTS) is a key region in the brainstem responsible for the hypoxic ventilatory response (HVR)…”
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Contribution of central μ-receptors to switching pulmonary C-fibers-mediated rapid shallow breathing into an apnea by fentanyl in anesthetized rats by Zhang, Zhenxiong, Zhang, Cancan, Zhuang, Jianguo, Xu, Fadi

“…Abstract Our previous study has shown that activating peripheral μ-receptors is necessary for switching the bronchopulmonary C-fibers (PCFs)-mediated rapid…”
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A critical role of acute bronchoconstriction in the mortality associated with high-dose sarin inhalation: Effects of epinephrine and oxygen therapies by Gundavarapu, Sravanthi, Zhuang, Jianguo, Barrett, Edward G., Xu, Fadi, Russell, Robert G., Sopori, Mohan L.

“…Sarin is an organophosphate nerve agent that is among the most lethal chemical toxins known to mankind. Because of its vaporization properties and ease and low…”
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Postnatal development of right atrial injection of capsaicin-induced apneic response in rats by Wang, Rurong, Xu, Fadi

“…Pathophysiology Program, Lovelace Respiratory Research Institute, Albuquerque, New Mexico Submitted 24 January 2006 ; accepted in final form 21 March 2006…”
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Opioid μ-receptors in medullary raphe region affect the hypoxic ventilation in anesthetized rats by Zhang, Zhenxiong, Xu, Fadi, Zhang, Cancan, Liang, Xiaomin

“…Abstract Opioids can attenuate the peripheral chemoreceptor-mediated hypoxic ventilatory response (HVR) by acting on central μ-type opioid receptors. Since the…”
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IL-1β acutely increases pulmonary SP and permeability without associated changes in airway resistance and ventilation in anesthetized rats by Zhuang, Jianguo, Xu, Junyang, Zhang, Cancan, Xu, Fadi

“…Abstract Bronchopulmonary C-fibers (PCFs), when activated, promote substance P (SP) release, increase microvascular leak, and produce bronchoconstriction and…”
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Hyperventilation evoked by activation of the vicinity of the caudal inferior olivary nucleus depends on the fastigial nucleus in anesthetized rats by Zhuang, Jianguo, Xu, Fadi, Frazier, Donald T

“…1 Pathophysiology Program, Lovelace Respiratory Research Institute, Albuquerque, New Mexico; and 2 Department of Physiology, University of Kentucky, Lexington,…”
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Respiratory syncytial virus infection in anesthetized weanling rather than adult rats prolongs the apneic responses to right atrial injection of capsaicin by Peng, Wenhong, Zhuang, Jianguo, Harrod, Kevin S, Xu, Fadi

“…Pathophysiology Program, Lovelace Respiratory Research Institute, Albuquerque, New Mexico Submitted 18 December 2006 ; accepted in final form 14 March 2007…”
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Systemic 8-OH-DPAT challenge causes hyperventilation largely via activating pre-botzinger complex 5-HT1A receptors by Zhuang, Jianguo, Xu, Fadi

“…•Activation of PBC 5-HT1A receptors induces tachypnea via disinhibition of local GABAA neurons; however, the role of these receptors in the respiratory…”
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Inhalation of the nerve gas sarin impairs ventilatory responses to hypercapnia and hypoxia in rats by Zhuang, Jianguo, Xu, Fadi, Campen, Matthew J., Zhang, Cancan, Pena-Philippides, Juan C., Sopori, Mohan L.

“…Sarin, a highly toxic nerve gas, is believed to cause bronchoconstriction and even death primarily through respiratory failure; however, the mechanism…”
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