Search Results - "FABIAN, Carol"
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Tamoxifen: Will Less Equal More in Women with Precancerous Breast Disease?
Published in Clinical cancer research (01-07-2021)“…Similar risk reduction but fewer side effects would predict more uptake and compliance with low (5 mg) versus full (20 mg) dose tamoxifen. Benefit with low…”
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Will a Low-Dose Option Improve Uptake of Tamoxifen for Breast Cancer Risk Reduction?
Published in Journal of clinical oncology (01-07-2019)Get full text
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Prevention and Monitoring of Cardiac Dysfunction in Survivors of Adult Cancers: American Society of Clinical Oncology Clinical Practice Guideline
Published in Journal of clinical oncology (10-03-2017)“…Purpose Cardiac dysfunction is a serious adverse effect of certain cancer-directed therapies that can interfere with the efficacy of treatment, decrease…”
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American Society of Clinical Oncology position statement on obesity and cancer
Published in Journal of clinical oncology (01-11-2014)“…Rates of obesity have increased significantly over the last three decades in the United States and globally. In addition to contributing to heart disease and…”
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Goserelin for Ovarian Protection during Breast-Cancer Adjuvant Chemotherapy
Published in The New England journal of medicine (05-03-2015)“…Women with hormone-receptor–negative breast cancer who received goserelin with adjuvant chemotherapy had less amenorrhea and better fertility at 2 years after…”
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Use of Endocrine Therapy for Breast Cancer Risk Reduction: ASCO Clinical Practice Guideline Update
Published in Journal of clinical oncology (20-11-2019)“…To update the ASCO guideline on pharmacologic interventions for breast cancer risk reduction and provide guidance on clinical issues that arise when deciding…”
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Reduced-Frequency Endocrine Therapy and Challenges of Noninferiority Study Designs
Published in JAMA oncology (01-05-2023)Get more information
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Exemestane for Breast-Cancer Prevention in Postmenopausal Women
Published in The New England journal of medicine (23-06-2011)“…In postmenopausal women at increased risk for breast cancer, exemestane reduced the annual incidence of invasive breast cancer by 65% after a median follow-up…”
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Use of Pharmacologic Interventions for Breast Cancer Risk Reduction: American Society of Clinical Oncology Clinical Practice Guideline
Published in Journal of clinical oncology (10-08-2013)“…To update the 2009 American Society of Clinical Oncology guideline on pharmacologic interventions for breast cancer (BC) risk reduction. A systematic review of…”
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A novel Bayesian adaptive design incorporating both primary and secondary endpoints for randomized IIB chemoprevention study of women at increased risk for breast cancer
Published in Current controlled trials in cardiovascular medicine (05-12-2022)“…Our randomized controlled clinical trial will explore the potential of bazedoxifene plus conjugated estrogen to modulate breast tissue-based risk biomarkers as…”
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The flaxseed lignan secoisolariciresinol diglucoside decreases local inflammation, suppresses NFκB signaling, and inhibits mammary tumor growth
Published in Breast cancer research and treatment (01-02-2019)“…Purpose Exposure to the polyphenolic plant lignan secoisolariciresinol diglucoside (SDG) and its metabolite enterolactone (ENL) has been associated with…”
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Early Detection of Ovarian Cancer using the Risk of Ovarian Cancer Algorithm with Frequent CA125 Testing in Women at Increased Familial Risk - Combined Results from Two Screening Trials
Published in Clinical cancer research (15-07-2017)“…Women at familial/genetic ovarian cancer risk often undergo screening despite unproven efficacy. Research suggests each woman has her own CA125 baseline;…”
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Omega-3 fatty acids for breast cancer prevention and survivorship
Published in Breast cancer research : BCR (04-05-2015)“…Women with evidence of high intake ratios of the marine omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) relative to the omega-6…”
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Final Analysis of the Prevention of Early Menopause Study (POEMS)/SWOG Intergroup S0230
Published in JNCI : Journal of the National Cancer Institute (01-02-2019)“…Premature menopause is a serious long-term side effect of chemotherapy. We evaluated long-term pregnancy and disease-related outcomes for patients in…”
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Germline BRCA mutation evaluation in a prospective triple-negative breast cancer registry: implications for hereditary breast and/or ovarian cancer syndrome testing
Published in Breast cancer research and treatment (01-06-2014)“…NCCN guidelines recommend genetic testing for all triple-negative breast cancer (TNBC) patients aged ≤60 years. However, due to the lack of prospective…”
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Effects of Weight Loss and Weight Regain on Circulating Biomarkers in Overweight/Obese Breast Cancer Survivors Enrolled in a Weight Loss Trial in the Rural Midwest
Published in Cancer epidemiology, biomarkers & prevention (01-07-2020)“…Obesity is associated with worse breast cancer prognosis, however little is known about the level of weight loss required to improve pathway biomarkers. The…”
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Phase II Study of Eribulin Mesylate, a Halichondrin B Analog, in Patients With Metastatic Breast Cancer Previously Treated With an Anthracycline and a Taxane
Published in Journal of clinical oncology (20-06-2009)“…Eribulin mesylate (E7389), a nontaxane microtubule dynamics inhibitor, is a structurally simplified, synthetic analog of the marine natural product…”
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Adiponectin: a risk biomarker and attractive target for chemoprevention
Published in Journal of clinical oncology (10-01-2012)Get full text
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Translating energy balance research from the bench to the clinic to the community: Parallel animal‐human studies in cancer
Published in CA: a cancer journal for clinicians (01-07-2023)“…Advances in energy balance and cancer research to date have largely occurred in siloed work in rodents or patients. However, substantial benefit can be derived…”
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Breast cancer and fertility preservation
Published in Fertility and sterility (01-04-2011)“…Objective To review the benefits of adjuvant systemic therapy given to women with breast cancer of reproductive age, its effects on fertility, and options for…”
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