Search Results - "F.M., Ruemmele"

Management Guidelines of Eosinophilic Esophagitis in Childhood by Papadopoulou, A., Koletzko, S., Heuschkel, R., Dias, J.A., Allen, K.J., Murch, S.H., Chong, S., Gottrand, F., Husby, S., Lionetti, P., Mearin, M.L., Ruemmele, F.M., Schäppi, M.G., Staiano, A., Wilschanski, M., Vandenplas, Y.

“…ABSTRACT Objectives: Eosinophilic esophagitis (EoE) represents a chronic, immune/antigen‐mediated esophageal disease characterized clinically by symptoms…”
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Diagnostic Approach and Management of Cowʼs-Milk Protein Allergy in Infants and Children: ESPGHAN GI Committee Practical Guidelines by Koletzko, S, Niggemann, B, Arato, A, Dias, J.A, Heuschkel, R, Husby, S, Mearin, M.L, Papadopoulou, A, Ruemmele, F.M, Staiano, A, Schäppi, M.G, Vandenplas, Y

“…OBJECTIVES:This guideline provides recommendations for the diagnosis and management of suspected cowʼs-milk protein allergy (CMPA) in Europe. It presents a…”
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A Practical Guide for the Diagnosis of Primary Enteric Nervous System Disorders by Schäppi, M.G., Staiano, A., Milla, P.J., Smith, V.V., Dias, J.A., Heuschkel, R., Husby, S., Mearin, M.L., Papadopoulou, A., Ruemmele, F.M., Vandenplas, Yvan, Koletzko, S.

“…ABSTRACT Objective: Primary gastrointestinal neuropathies are a heterogeneous group of enteric nervous system (ENS) disorders that continue to cause…”
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Diagnostic Approach and Management of Cow's‐Milk Protein Allergy in Infants and Children by Koletzko, S., Niggemann, B., Arato, A., Dias, J.A., Heuschkel, R., Husby, S., Mearin, M.L., Papadopoulou, A., Ruemmele, F.M., Staiano, A., Schäppi, M.G., Vandenplas, Y.

“…ABSTRACT Objectives: This guideline provides recommendations for the diagnosis and management of suspected cow's‐milk protein allergy (CMPA) in Europe. It…”
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The Susceptibility to Fas-Induced Apoptosis in Normal Enterocytes Is Regulated on the Level of cIAP1 and 2 by Ruemmele, F.M., Beaulieu, J.F., O'Connell, J., Bennett, M.W., Seidman, E.G., Lentze, M.J.

“…Various members of the tumor necrosis factor receptor superfamily are implicated in the regulation of enterocyte apoptosis. Previously, we observed that human…”
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Susceptibility to FAS-induced apoptosis in human nontumoral enterocytes: Role of costimulatory factors by Ruemmele, F.M., Russo, P., Beaulieu, J.-F., Dionne, S., Levy, E., Lentze, M.J., Seidman, E.G.

“…FAS–FAS ligand interaction has been implicated in increased enterocyte apoptosis seen in immune‐mediated bowel injury. However, scant information exists on the…”
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Consensus guidelines of ECCO/ESPGHAN on the medical management of pediatric Crohn's disease by Ruemmele, F.M., Veres, G., Kolho, K.L., Griffiths, A., Levine, A., Escher, J.C., Amil Dias, J., Barabino, A., Braegger, C.P., Bronsky, J., Buderus, S., Martín-de-Carpi, J., De Ridder, L., Fagerberg, U.L., Hugot, J.P., Kierkus, J., Kolacek, S., Koletzko, S., Lionetti, P., Miele, E., Navas López, V.M., Paerregaard, A., Russell, R.K., Serban, D.E., Shaoul, R., Van Rheenen, P., Veereman, G., Weiss, B., Wilson, D., Dignass, A., Eliakim, A., Winter, H., Turner, D.

“…Children and adolescents with Crohn’s disease (CD) present often with a more complicated disease course compared to adult patients. In addition, the potential…”
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Efficacy of adalimumab as first-line therapy in pediatric Crohn's disease by Zenzeri, L., Pigneur, B., Norsa, L., Farinelli, E., Esposito, S., Ruemmele, F.M.

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Severe Food Allergy as a Variant of IPEX Syndrome Caused by a Deletion in a Noncoding Region of the FOXP3 Gene by Torgerson, Troy R, Linane, Avriel, Moes, Nicolette, Anover, Stephanie, Mateo, Véronique, Rieux–Laucat, Frédéric, Hermine, Olivier, Vijay, Shashi, Gambineri, Eleonora, Cerf–Bensussan, Nadine, Fischer, Alain, Ochs, Hans D, Goulet, Olivier, Ruemmele, Frank M

“…Background & Aims: Immune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX; OMIM 304930) syndrome is a congenital syndrome characterized by…”
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Compartmentalized expression of Th1 and Th17 cytokines in pediatric inflammatory bowel diseases by Verdier, J., Begue, B., Cerf‐Bensussan, N., Ruemmele, F.M.

“…Background: Interleukin (IL)‐23, IL‐17A, IL‐17F, and interferon‐gamma (IFN‐γ) are important mediators of inflammatory colitis and are potential therapeutic…”
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Cutaneous manifestations of immune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX) syndrome by Halabi-Tawil, M., Ruemmele, F.M., Fraitag, S., Rieux-Laucat, F., Neven, B., Brousse, N., De Prost, Y., Fischer, A., Goulet, O., Bodemer, C.

“…Summary Background  Immune dysregulation, polyendocrinopathy, enteropathy, X‐linked (IPEX) syndrome is a rare disorder characterized by neonatal autoimmune…”
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Efficacy of methotrexate in pediatric Crohn's disease: A French multicenter study by Uhlen, S., Belbouab, R., Narebski, K., Goulet, O., Schmitz, J., Cézard, J.P., Turck, D., Ruemmele, F.M.

“…Background: Immunosuppressors play a major role in maintaining remission in Crohn's disease (CD). In patients who do not tolerate or escape therapy with…”
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Butyrate induced Caco-2 cell apoptosis is mediated via the mitochondrial pathway by Ruemmele, F M, Schwartz, S, Seidman, E G, Dionne, S, Levy, E, Lentze, M J

“…Background:During the process of tumorigenesis most colon cancer cells acquire resistance to apoptosis. The short chain fatty acid butyrate is well established…”
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P384 Relationship between adalimumab concentration and efficacy for the maintenance of clinical remission in pediatric patients with moderate to severe Crohn's disease by Sharma, S., Pradhan, R., Thakkar, R., Robinson, A., Hyams, J., Rosh, J., Ruemmele, F.M., Awni, W.

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P385 Relationship between adalimumab concentration and efficacy for the induction of clinical remission in pediatric patients with moderate to severe Crohn's disease by Pradhan, R., Sharma, S., Thakkar, R., Robinson, A., Hyams, J., Rosh, J., Ruemmele, F.M., Awni, W.

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Interleukin-17 is a potent immuno-modulator and regulator of normal human intestinal epithelial cell growth by Schwartz, S., Beaulieu, J.F., Ruemmele, F.M.

“…Upregulation of the T-cell derived cytokine interleukin (IL-17) was reported in the inflamed intestinal mucosa of patients with inflammatory bowel disorders…”
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Microbial induction of CARD15 expression in intestinal epithelial cells via toll-like receptor 5 triggers an antibacterial response loop by Begue, B., Dumant, C., Bambou, J.C., Beaulieu, J.F., Chamaillard, M., Hugot, J.P., Goulet, O., Schmitz, J., Philpott, D.J., Cerf-Bensussan, N., Ruemmele, F.M.

“…With the discovery of CARD15 as susceptibility gene for Crohn's disease (CD) a first link to a potential defect in the innate immune system was made. In this…”
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P411 Pharmacokinetics of adalimumab in pediatric patients with moderate to severe Crohn's disease by Eckert, D., Mensing, S., Sharma, S., Thakkar, R., Robinson, A., Hyams, J., Rosh, J., Ruemmele, F.M., Awni, W.

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Lipopolysaccharide modulation of normal enterocyte turnover by toll-like receptors is mediated by endogenously produced tumour necrosis factor α by Ruemmele, F M, Beaulieu, J F, Dionne, S, Levy, E, Seidman, E G, Cerf-Bensussan, N, Lentze, M J

“…Background: Circulating levels of endotoxin (or lipopolysaccharide (LPS)) and anti-endotoxin antibodies are increased in patients with inflammatory bowel…”
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Pro-inflammatory environment dictates the IL-17-producing capacity of human invariant NKT cells by Moreira-Teixeira, L., Resende, M., Coffre, M., Devergne, O., J.P., Herbeuval, Hermine, O., Schneider, E., Rogge, L., F.M., Ruemmele, M., Dy, Cordeiro-Da-Silva, Anabela, de Moraes M.C., Leite

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