Search Results - "F. Villinger"

Costimulation Blockade Alters Germinal Center Responses and Prevents Antibody‐Mediated Rejection by Kim, E. J., Kwun, J., Gibby, A. C., Hong, J. J., Farris, A. B., Iwakoshi, N. N., Villinger, F., Kirk, A. D., Knechtle, S. J.

“…De novo donor‐specific antibody (DSA) after organ transplantation promotes antibody‐mediated rejection (AMR) and causes late graft loss. Previously, we…”
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Neutralizing BAFF/APRIL With Atacicept Prevents Early DSA Formation and AMR Development in T Cell Depletion Induced Nonhuman Primate AMR Model by Kwun, J., Page, E., Hong, J. J., Gibby, A., Yoon, J., Farris, A. B., Villinger, F., Knechtle, S.

“…Depletional strategies directed toward achieving tolerance induction in organ transplantation have been associated with an increased incidence and risk of…”
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Early treatment of SIV+ macaques with an α 4 β 7 mAb alters virus distribution and preserves CD4 + T cells in later stages of infection by Santangelo, P J, Cicala, C, Byrareddy, S N, Ortiz, K T, Little, D, Lindsay, K E, Gumber, S, Hong, J J, Jelicic, K, Rogers, K A, Zurla, C, Villinger, F, Ansari, A A, Fauci, A S, Arthos, J

“…Integrin α β mediates the trafficking of leukocytes, including CD4 T cells, to lymphoid tissues in the gut. Virus mediated damage to the gut is implicated in…”
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Antibody‐Mediated Rejection in Sensitized Nonhuman Primates: Modeling Human Biology by Burghuber, C. K., Kwun, J., Page, E. J., Manook, M., Gibby, A. C., Leopardi, F. V., Song, M., Farris, A. B., Hong, J. J., Villinger, F., Adams, A. B., Iwakoshi, N. N., Knechtle, S. J.

“…We have established a model of sensitization in nonhuman primates and tested two immunosuppressive regimens. Animals underwent fully mismatched skin…”
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CD4+ and CD8+ T-Cell Responses to Latent Antigen EBNA-1 and Lytic Antigen BZLF-1 during Persistent Lymphocryptovirus Infection of Rhesus Macaques by Leskowitz, R M, Zhou, X Y, Villinger, F, Fogg, M H, Kaur, A, Lieberman, P M, Wang, F, Ertl, H C

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OP 2.2 – 00200 Characterization of the SIV tissue reservoir transcriptional environment at the single focus level during ART and post ATI by M. Arif, S. Samer, C.T. Thuruthiyil, M.D. Mcraven, F. Villinger, E. Martinelli, R. Lorenzo-Redondo, T. Hope

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Ancient co-speciation of simian foamy viruses and primates by Switzer, William M, Salemi, Marco, Shanmugam, Vedapuri, Gao, Feng, Cong, Mian-er, Kuiken, Carla, Bhullar, Vinod, Beer, Brigitte E, Vallet, Dominique, Gautier-Hion, Annie, Tooze, Zena, Villinger, Francois, Holmes, Edward C, Heneine, Walid

“…Although parasite-host co-speciation is a long-held hypothesis, convincing evidence for long-term co-speciation remains elusive, largely because of small…”
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Simian Immunodeficiency Virus (SIV) Infection Influences the Level and Function of Regulatory T Cells in SIV-Infected Rhesus Macaques but Not SIV-Infected Sooty Mangabeys by PEREIRA, L. E, VILLINGER, F, ONLAMOON, N, BRYAN, P, CARDONA, A, PATTANAPANYSAT, K, MORI, K, HAGEN, S, PICKER, L, ANSARI, A. A

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PP 1.38 – 00212 Characterization of SIV infected mast cells in early foci of rebound after ATI and HIV infection of primary mast cells in tissue culture models reveals an important new player in viral persistence and pathogenesis by T. Hope, Y. Thomas, S. Samer, M. Shoaib Arif, I. Clerc, A.M. Carias, E.J. Allen, M.D. McRaven, D.A. Vanover, M. Arainga Ramirez, P.J. Santangelo, F. Villinger, E. Martinelli

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PP 1.6 – 00047LAIR-1 is a negative regulator of SIV-specific CD8 T cells during chronic SIV infection by V. Velu, S. Govindaraj, A. Arunkumar Sharma, S. Ali, H. Babu, K. Busman-Sahay, S. Bosinger, J. Estes, R.-P. Sekaly, R. Amara, F. Villinger

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Adenovirus-based vaccines against rhesus lymphocryptovirus EBNA-1 induce expansion of specific CD8+ and CD4+ T cells in persistently infected rhesus macaques by Leskowitz, R, Fogg, M H, Zhou, X Y, Kaur, A, Silveira, E L V, Villinger, F, Lieberman, P M, Wang, F, Ertl, H C

“…The impact of Epstein-Barr virus (EBV) on human health is substantial, but vaccines that prevent primary EBV infections or treat EBV-associated diseases are…”
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Utilising correlative PET/CT and multiscale imaging to define the dynamics of SIV-infected cells from early ART initiation to the rebound after analytic treatment interruption by T. Hope, M.S. Arif, Y. Thomas, I. Clerc, A. Carias, E. Allen, M. Mcraven, M. Ramirez, P. Santangelo, F. Villinger

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Differential induction of activation and apoptosis by TCR signaling in sooty mangabeys and rhesus macaques by Yu, S, Rogers, K, Villinger, F, Kaur, A

“…Doc number: P36…”
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Pharmacokinetics, toxicity, and functional studies of the selective Kv1.3 channel blocker 5-(4-phenoxybutoxy)psoralen in rhesus macaques by Pereira, L E, Villinger, F, Wulff, H, Sankaranarayanan, A, Raman, G, Ansari, A A

“…The small molecule 5-(4-phenoxybutoxy)psoralen (PAP-1) is a selective blocker of the voltage-gated potassium channel Kv1.3 that is highly expressed in cell…”
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IL-15 is superior to IL-2 in the generation of long-lived antigen specific memory CD4 and CD8 T cells in rhesus macaques by Villinger, F., Miller, R., Mori, K., Mayne, A.E., Bostik, P., Sundstrom, J.B., Sugimoto, C., Ansari, A.A.

“…Using tetanus toxoid (TT) and influenza (Flu) immunization of rhesus macaques as a model, the effect of IL-2 and IL-15 on the generation and maintenance of…”
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Folate Is Associated with Risk of Hyperparathyroidism: Results from the National Health And Nutrition Examination Survey by Coakley, K.E, Stevens, V, Halkar, R, Villinger, F, Amancha, P.K, Safley, S.A, Muller, S, Weber, C.J, Sharma, J

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Efficient entry inhibition of human and nonhuman primate immunodeficiency virus by cell surface-expressed gp41-derived peptides by Zahn, R C, Hermann, F G, Kim, E-Y, Rett, M D, Wolinsky, S M, Johnson, R P, Villinger, F, von Laer, D, Schmitz, J E

“…Membrane-anchored C-peptides (for example, maC46) derived from human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein gp41 effectively inhibit HIV-1…”
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Hematology and serum chemistry values of sooty mangabeys (Cercocebus atys): comparison with rhesus monkeys by Sharma, P., Chennareddi, L., Greene-Hartsfield, E.Z., Villinger, F., Cohen, J.K., Herndon, J.G.

“…Background The sooty mangabey is a vulnerable West African species that naturally harbors simian immunodeficiency virus (SIV) without pathological symptoms. We…”
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Recombinant IL-21 induces perforin and granzyme B in total and virus specific CD8 Tcells in acute and early stages of SIV infection in rhesus macaques by Pallikkuth, S, Micci, L, Ende, Z, Rogers, K, Silvestry, G, Villinger, F, Paiardini, M, Pahwa, S

“…Doc number: P13…”
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Early pro-inflammatory host response to recombinant HSV-SIV vaccination in sooty mangabeys by Rout, N, Yu, S, Varner, V, Kasala-Hallinan, C, Rogers, K, Sen, J, Knipe, D, Villinger, F, Kaur, A

“…Doc number: O17…”
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