Search Results - "F. Peyvandi"
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Advances in the treatment of bleeding disorders
Published in Journal of thrombosis and haemostasis (01-11-2016)“…Summary Historically, the bleeding episodes in subjects with coagulation disorders were treated with substitution therapy, initially with whole blood and fresh…”
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A critical appraisal of one‐stage and chromogenic assays of factor VIII activity
Published in Journal of thrombosis and haemostasis (01-02-2016)“…Summary Accurate and precise potency determination by manufacturers of different types of factor VIII product (plasma‐derived and recombinant FVIII [rFVIII])…”
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Factor XIII deficiency diagnosis: Challenges and tools
Published in International journal of laboratory hematology (01-02-2018)“…Factor XIII deficiency (FXIIID) is a rare hereditary bleeding disorder arising from heterogeneous mutations, which can lead to life‐threatening hemorrhage. The…”
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Consensus on the standardization of terminology in thrombotic thrombocytopenic purpura and related thrombotic microangiopathies
Published in Journal of thrombosis and haemostasis (01-02-2017)“…Essentials An international collaboration provides a consensus for clinical definitions. This concerns thrombotic microangiopathies and thrombotic…”
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Coagulation factor activity and clinical bleeding severity in rare bleeding disorders: results from the European Network of Rare Bleeding Disorders
Published in Journal of thrombosis and haemostasis (01-04-2012)“…Background: The European Network of Rare Bleeding Disorders (EN‐RBD) was established to bridge the gap between knowledge and practise in the care of patients…”
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Future of coagulation factor replacement therapy
Published in Journal of thrombosis and haemostasis (01-06-2013)“…Summary Over a million patients worldwide currently suffer from hemophilia and other congenital clotting factor deficiencies. Patients affected with hemophilia…”
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Rare bleeding disorders - bleeding assessment tools, laboratory aspects and phenotype and therapy of FXI deficiency
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01-05-2014)“…Summary Rare bleeding disorders (RBDs) are inherited deficiencies of coagulation factors such as fibrinogen, factor (F) II, FV, FVII, combined FV+FVIII, FX,…”
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Caplacizumab reduces the frequency of major thromboembolic events, exacerbations and death in patients with acquired thrombotic thrombocytopenic purpura
Published in Journal of thrombosis and haemostasis (01-07-2017)“…Essentials Acquired thrombotic thrombocytopenic purpura (aTTP) is linked with significant morbidity/mortality. Caplacizumab's effect on major thromboembolic…”
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Molecular diagnosis of von Willebrand disease
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01-03-2017)“…The role of molecular characterization in the diagnosis of von Willebrand disease (VWD) is not essential if the patients have been extensively investigated…”
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Evolution of Haemophilia Care in Europe: 10 years of the principles of care
Published in Orphanet journal of rare diseases (13-07-2020)“…Abstract Introduction The European principles of care in haemophilia marked their first decade in 2018. These guiding principles were the beginning of the…”
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Fibrinogen replacement therapy for congenital fibrinogen deficiency
Published in Journal of thrombosis and haemostasis (01-09-2011)“…This review of published studies was conducted to derive data on patients with congenital fibrinogen deficiency (CFD), including dosing of fibrinogen…”
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Phase 3 study of recombinant von Willebrand factor in patients with severe von Willebrand disease who are undergoing elective surgery
Published in Journal of thrombosis and haemostasis (01-01-2019)“…Summary Essentials Recombinant von Willebrand factor (rVWF) is effective in von Willebrand disease (VWD). A phase 3 study of rVWF, with/without recombinant…”
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SIPPET: methodology, analysis and generalizability
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01-05-2017)“…The development of anti‐FVIII neutralizing alloantibodies (inhibitors), occurring in about one‐third of previously untreated patients (PUPs) with severe…”
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Gynecological and obstetrical manifestations of inherited bleeding disorders in women
Published in Journal of thrombosis and haemostasis (01-07-2011)“…Patients affected by bleeding disorders present a wide spectrum of clinical symptoms that vary from a mild or moderate bleeding tendency to significant…”
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Plasma ADAMTS‐13 levels and the risk of myocardial infarction: an individual patient data meta‐analysis
Published in Journal of thrombosis and haemostasis (01-08-2015)“…Summary Background Low ADAMTS‐13 levels have been repeatedly associated with an increased risk of ischemic stroke, but results concerning the risk of…”
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Reduced circulating FABP2 in patients with moderate to severe COVID-19 may indicate enterocyte functional change rather than cell death
Published in Scientific reports (05-11-2022)“…The gut is of importance in the pathology of COVID-19 both as a route of infection, and gut dysfunction influencing the severity of disease. Systemic changes…”
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Inhibitor development in haemophilia
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01-01-2017)Get full text
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Minimal factor XIII activity level to prevent major spontaneous bleeds: reply
Published in Journal of thrombosis and haemostasis (01-11-2017)Get full text
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Timing and severity of inhibitor development in recombinant versus plasma‐derived factor VIII concentrates: a SIPPET analysis
Published in Journal of thrombosis and haemostasis (01-01-2018)“…Essentials Recombinant factor VIII (rFVIII) was contrasted with plasma‐derived FVIII (pdFVIII). In previously untreated patients with hemophilia A, rFVIII led…”
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