Search Results - "F G Walz, Jr"

Mapping of genes for cytochromes P-450b, P-450e, P-450g, and P-450h in the rat. Demonstration of two gene clusters with P450-b,e localized on chromosome 1 by Rampersaud, A., Walz, F.G.

“…Inbred ACI, WF, and RCS rats having characteristic markers for albino (c), hemoglobin beta-chain (Hbb), and pink-eyed dilution (p) on chromosome 1 and…”
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At Least Six Forms of Extremely Homologous Cytochromes P-450 in Rat Liver are Encoded at Two Closely Linked Genetic Loci by Rampersaud, Arfaan, Walz, Frederick G.

“…A subpopulation of phenobarbital-induced cytochrome P-450 in rat liver has been shown to consist of four closely related forms of the enzyme that appeared to…”
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Multiple, immunoidentical forms of phenobarbital-induced rat liver cytochromes P-450 are encoded by different mRNAs by Walz, F G, Vlasuk, G P, Omiecinski, C J, Bresnick, E, Thomas, P E, Ryan, D E, Levin, W

“…It was shown previously that four immunochemically identical forms of phenobarbital-induced hepatic cytochrome P-450 exist in unique combinations which…”
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Phenobarbital induction of rat liver cytochromes P-450b and P-450e. Quantitation of specific RNAs by hybridization to synthetic oligodeoxyribonucleotide probes by Omiecinski, C J, Walz, F G, Vlasuk, G P

“…Cytochromes P-450b and P-450e are extremely homologous and immunochemically indistinguishable proteins that are coordinately induced by phenobarbital in rat…”
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Genetic and developmental diversity of hepatic cytochromes P450. Warfarin and progesterone metabolism by hepatic microsomes from four inbred strains of rat by Kitareewan, S, Walz, Jr, F G

“…Hepatic microsomes from immature and sexually mature male and female ACI/SEGHsd, F344/NHsd, SHR/NHsd, and WKY/NCrl inbred rats were used to study cytochrome…”
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Cytochrome P-450 polypeptides in pulmonary microsomes from rats by Rampersaud, A, Walz, Jr, F G

“…Pulmonary microsomal polypeptides from different strains of rats were resolved using two-dimensional electrophoresis and were further characterized by in situ…”
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Spermine stabilization of folded ribonuclease T1 by F G Walz, Jr, S Kitareewan

“…The interaction of ribonuclease T1 with tetraprotonated spermine (SPM4+), Mg2+, phosphate and other ionic ligands at pH 6.0 was investigated in binding…”
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Null phenotype for cytochrome P450 2B2 in the rat results from a deletion of its structural gene by Omiecinski, C J, Ramsden, R, Rampersaud, A, Walz, Jr, F G

“…The absence of phenobarbital (PB)-inducible cytochrome P450 2B2 (CYP2B2) in hepatic microsomes from Marshall 520 (M520) and Wistar Munich (WM) inbred strains…”
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Polymorphisms of four hepatic cytochromes P-450 in twenty-eight inbred strains of rat by ARFAAN RAMPERSAUD, WALZ, F. G. JR

“…Two-dimensional gel electrophoresis of hepatic microsomes from phenobarbital-treated animals was used to analyze electrophoretic/regulatory polymorphisms for…”
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Multiplicity, strain differences, and topology of phenobarbital-induced cytochromes P-450 in rat liver microsomes by Vlasuk, George P, Ghrayeb, John, Ryan, Dene E, Reik, Linda, Thomas, Paul E, Levin, Wayne, Walz, Frederick G

“…The multiplicity of phenobarbital-induced cytochromes P-450 in live microsomes from male rats was investigated by using two-dimensional gel electrophoresis,…”
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A regulatory polymorphism for rat hepatic cytochrome P-450g by Rampersaud, A, Bandiera, S, Ryan, D E, Levin, W, Thomas, P E, Walz, Jr, F G

“…Rat hepatic cytochrome P-450g is a male-specific hemoprotein found at significant levels only in adult animals. In the present study, two-dimensional gel…”
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Probing Functional Perfection in Substructures of Ribonuclease T1:  Double Combinatorial Random Mutagenesis Involving Asn43, Asn44, and Glu46 in the Guanine Binding Loop by Kumar, Kapil, Walz, Frederick G

“…Combinatorial random mutageneses involving either Asn43 with Asn44 (set 1) or Glu46 with an adjacent insertion (set 2) were undertaken to explore the…”
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Three-Dimensional Structure of Ribonuclease T1 Complexed with an Isosteric Phosphonate Substrate Analogue of GpU:  Alternate Substrate Binding Modes and Catalysis by Arni, Raghuvir K, Watanabe, Leandra, Ward, Richard J, Kreitman, Robert J, Kumar, Kapil, Walz, Frederick G

“…The X-ray crystal structure of a complex between ribonuclease T1 and guanylyl(3‘-6‘)-6‘-deoxyhomouridine (GpcU) has been determined at 2.0 Å resolution. This…”
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Probing Functional Perfection in Substructures of Ribonuclease T sub(1): Double Combinatorial Random Mutagenesis Involving Asn43, Asn44, and Glu46 in the Guanine Binding Loop by Kumar, K, Walz, FG Jr

“…Combinatorial random mutageneses involving either Asn43 with Asn44 (set 1) or Glu46 with an adjacent insertion (set 2) were undertaken to explore the…”
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Comparisons of highly purified hepatic microsomal cytochromes P-450 from Holtzman and Long-Evans rats by Ryan, D E, Wood, A W, Thomas, P E, Walz, Jr, F G, Yuan, P M, Shively, J E, Levin, W

“…The present study describes the purification and characterization of strain variant forms of a major phenobarbital-inducible microsomal hemoprotein, cytochrome…”
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Adult-male-specific S-warfarin (11S-OH) and progesterone (20β-OH) keto-reductases in rat hepatic microsomes are not identical by Apanovitch, Don, Walz, Frederick G.

“…Adult-male-specific reductase activities in rat hepatic microsomes use NADPH to reduce S-warfarin and progesterone to their 11S-OH and 20β-OH products,…”
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Upstream subsite interactions for oligonucleotide binding with ribonuclease T1 by Walz, Jr, F G

“…Ribonuclease T1 (RNase T1) specifically cleaves RNA at guanylyl residues. Previous studies revealed the presence of an enzyme-subsite interaction for adenosine…”
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Exocyclic-keto reductase activities for progesterone and S-warfarin in hepatic microsomes from adult male rats by Apanovitch, D, Kitareewan, S, Walz, Jr, F G

“…Hepatic microsomes from adult male rats representing six inbred strains catalyzed quantitatively significant, NADPH dependent reductions of progesterone to the…”
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Three-dimensional structure of Gln25-ribonuclease T1 at 1.84-A resolution: structural variations at the base recognition and catalytic sites by Arni, R K, Pal, G P, Ravichandran, K G, Tulinsky, A, Walz, Jr, F G, Metcalf, P

“…The structure of the Gln25 variant of ribonuclease T1 (RNase T1) crystallized at pH 7 and at high ionic strength has been solved by molecular replacement using…”
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Three-Dimensional Structure of Ribonuclease T sub(1) Complexed with an Isosteric Phosphonate Substrate Analogue of GpU: Alternate Substrate Binding Modes and Catalysis by Arni, R K, Watanabe, L, Ward, R J, Kreitman, R J, Kumar, K, Walz, FG Jr

“…The X-ray crystal structure of a complex between ribonuclease T sub(1) and guanylyl(3'-6')-6'-deoxyhomouridine (GpcU) has been determined at 2.0 Ae resolution…”
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