Search Results - "Fırat, Seyhan"
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Sağlık kurumlarında çalışan personelin yeşil tedarik zinciri hakkında bilgi düzeylerinin belirlenmesi
Published in İşletme Araştırmaları Dergisi (01-03-2021)“…Amaç – Bu çalışmanın amacı, kaynakların sınırlı, atık depolama ve imha alanlarının yetersiz, tehlikeli madde kullanımı ve atılması ile ilgili personel…”
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Characteristics of Engineered Waste Materials Used for Road Subbase Layers
Published in KSCE journal of civil engineering (01-09-2020)“…Coal fly ash (FA) and basic oxygen furnace (BOF) slag are the by-products of coal combustion in power stations and steel plants, respectively. The disposal of…”
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Numerical investigation of stone columns in liquefiable soils
Published in Arabian journal of geosciences (01-03-2022)“…Under earthquake motions, effective stress decreases with pore water pressures. It falls to zero or near-zero values in saturated sandy soils, and…”
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The mediating role of job satisfaction in the relationship between quality of work life and turnover: The moderating role of gender
Published in İşletme Araştırmaları Dergisi (29-09-2020)“…Purpose – The purpose of this study is to examine-using a moderation role of gender- the mediating role of job satisfaction between quality of work life and…”
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Rho-kinase inhibitor, Y-27632, has an antinociceptive effect in mice
Published in European journal of pharmacology (10-07-2006)“…The possible antinociceptive effect of a Rho-kinase inhibitor, (+)-( R)- trans-4-(1-aminoethyl)- N-(4-pyridyl) cyclohexanecarboxamide dihydrochloride…”
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Role of cytokine gene polymorphisms on ramipril-altered inflammatory response and myocardial injury in patients undergoing coronary artery bypass surgery
Published in Cukurova Medical Journal (01-03-2017)“…Purpose: Ramipril is effective in treating inflammatory myocardial injury by reducing cytokines such as TNF-α, IL-6, and IL-8. In this study, we investigated…”
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Contribution of Rho-kinase in human gallbladder contractions
Published in European journal of pharmacology (01-07-2006)“…Rho/Rho-kinase-mediated pathway has been involved in a variety of physiological processes, including Ca 2+ sensitization, which enhances smooth muscle…”
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Soluble epoxide hydrolase inhibitor trifluoromethoxyphenyl‐3‐(1‐propionylpiperidin‐4‐yl)urea prevents hyperalgesia through regulating NLRC4 inflammasome‐related pro‐inflammatory and anti‐inflammatory signaling pathways in the lipopolysaccharide‐induced pain mouse model
Published in Drug development research (01-09-2021)“…Epoxyeicosatrienoic acids (EETs) have anti‐inflammatory effects and soluble epoxide hydrolase (sEH) inhibition might be a useful therapeutic approach to manage…”
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Rho kinase expression and its central role in ovine gallbladder contractions elicited by a variety of excitatory stimuli
Published in European journal of pharmacology (28-12-2005)“…Rho kinase has contractile activity, which induces Ca 2+ sensitization in various cells. Several receptors are linked to the Rho/Rho-kinase pathway. Therefore,…”
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Suppression of TLR4/MyD88/TAK1/NF-κB/COX-2 Signaling Pathway in the Central Nervous System by Bexarotene, a Selective RXR Agonist, Prevents Hyperalgesia in the Lipopolysaccharide-Induced Pain Mouse Model
Published in Neurochemical research (01-03-2021)“…A selective RXR agonist, bexarotene, has been shown to have anti-inflammatory, anti-nociceptive, and neuroprotective effects in several models of numerous…”
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NF‐κB activation mediates LPS‐or zymosan‐induced hypotension and inflammation reversed by BAY61‐3606, a selective Syk inhibitor, in rat models of septic and non‐septic shock
Published in Clinical and experimental pharmacology & physiology (01-02-2019)“…Summary We have previously demonstrated that the activation of the spleen tyrosine kinase (Syk)/inhibitory‐κB (IκB)‐α/nuclear factor‐κB (NF‐κB) p65 signalling…”
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Inhibition of mTOR protects against skeletal muscle and kidney injury following hindlimb ischemia-reperfusion in rats by regulating MEK1/ERK1/2 activity
Published in Cukurova Medical Journal (01-01-2022)“…Purpose: We have previously demonstrated that activation of the mammalian target of rapamycin (mTOR)/inhibitory-κB-α/nuclear factor-κB p65 signaling pathway…”
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Role of ACE I/D gene polymorphisms on the effect of ramipril in inflammatory response and myocardial injury in patients undergoing coronary artery bypass grafts
Published in European journal of clinical pharmacology (01-12-2014)“…Background Angiotensin-converting enzyme (ACE) inhibitors block angiotensin II formation and release bradykinin, which is effective in the regulation of…”
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The role of Syk/IĸB‐α/NF‐ĸB pathway activation in the reversal effect of BAY 61‐3606, a selective Syk inhibitor, on hypotension and inflammation in a rat model of zymosan‐induced non‐septic shock
Published in Clinical and experimental pharmacology & physiology (01-02-2018)“…Summary Spleen tyrosine kinase (Syk), a non‐receptor tyrosine kinase, plays an important role in allergic diseases and inflammation. Syk triggers several…”
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17 Ağustos 1999 Marmara Depreminde Sıkça Rastlanan Çatı Hasarları
Published in Politeknik Dergisi (01-02-2007)“…Deprem yer kabuğunun yavaş hareketleri sonucunda belirli bölgelerde meydana gelen gerilme birikiminin ani boşalması olayına denilmektedir. Depremde yapılar…”
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Contribution of RhoA/Rho-kinase/MEK1/ERK1/2/iNOS pathway to ischemia/reperfusion-induced oxidative/nitrosative stress and inflammation leading to distant and target organ injury in rats
Published in European journal of pharmacology (15-01-2014)“…The small G protein RhoA and its downstream effector Rho-kinase play an important role in various physiopathological processes including ischemia/reperfusion…”
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mTORC2 inhibition by JR-AB2-011 improves IL-1β-induced inflammation, catabolic response, and apoptosis in human chondrocytes through IκB-α/NF-κB p65
Published in Cellular and Molecular Biology (08-10-2024)“…Osteoarthritis (OA) is a very common chronic joint condition marked by inflammation and cartilage loss. mTOR is a well-known mediator of inflammation, cell…”
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Effects of 5,14-HEDGE, a 20-HETE mimetic, on lipopolysaccharide-induced changes in MyD88/TAK1/IKKβ/IκB-α/NF-κB pathway and circulating miR-150, miR-223, and miR-297 levels in a rat model of septic shock
Published in Inflammation research (01-09-2014)“…Objectives We have previously demonstrated that a stable synthetic analog of 20-hydroxyeicosatetraenoic acid (20-HETE), N -(20-hydroxyeicosa-5[ Z ],14[ Z…”
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Pro-inflammatory GPR75 and anti-apoptotic phospholipase signaling pathways contribute to the ameliorating effect of soluble epoxide hydrolase inhibition on chronic experimental autoimmune encephalomyelitis in mice
Published in Cellular and Molecular Biology (31-10-2023)Get full text
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