Search Results - "Förstner, Konrad"

High-resolution transcriptome maps reveal strain-specific regulatory features of multiple Campylobacter jejuni isolates by Dugar, Gaurav, Herbig, Alexander, Förstner, Konrad U, Heidrich, Nadja, Reinhardt, Richard, Nieselt, Kay, Sharma, Cynthia M

“…Campylobacter jejuni is currently the leading cause of bacterial gastroenteritis in humans. Comparison of multiple Campylobacter strains revealed a high…”
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Evolution of Resistance to a Last-Resort Antibiotic in Staphylococcus aureus via Bacterial Competition by Koch, Gudrun, Yepes, Ana, Förstner, Konrad U., Wermser, Charlotte, Stengel, Stephanie T., Modamio, Jennifer, Ohlsen, Knut, Foster, Kevin R., Lopez, Daniel

“…Antibiotic resistance is a key medical concern, with antibiotic use likely being an important cause. However, here we describe an alternative route to…”
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Grad-seq guides the discovery of ProQ as a major small RNA-binding protein by Smirnov, Alexandre, Förstner, Konrad U., Holmqvist, Erik, Otto, Andreas, Günster, Regina, Becher, Dörte, Reinhardt, Richard, Vogel, Jörg

“…The functional annotation of transcriptomes and identification of noncoding RNA (ncRNA) classes has been greatly facilitated by the advent of next-generation…”
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Ten simple rules for implementing electronic lab notebooks (ELNs) by Vandendorpe, Justine, Adam, Beatrix, Wilbrandt, Jeanne, Lindstädt, Birte, Förstner, Konrad U

“…[...]ELNs enable researchers to collaborate [3], whether within their own group or with others, through a common medium. [...]ELNs make an important…”
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In Vivo Cleavage Map Illuminates the Central Role of RNase E in Coding and Non-coding RNA Pathways by Chao, Yanjie, Li, Lei, Girodat, Dylan, Förstner, Konrad U., Said, Nelly, Corcoran, Colin, Śmiga, Michał, Papenfort, Kai, Reinhardt, Richard, Wieden, Hans-Joachim, Luisi, Ben F., Vogel, Jörg

“…Understanding RNA processing and turnover requires knowledge of cleavages by major endoribonucleases within a living cell. We have employed TIER-seq…”
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Global transcriptional start site mapping using differential RNA sequencing reveals novel antisense RNAs in Escherichia coli by Thomason, Maureen K, Bischler, Thorsten, Eisenbart, Sara K, Förstner, Konrad U, Zhang, Aixia, Herbig, Alexander, Nieselt, Kay, Sharma, Cynthia M, Storz, Gisela

“…While the model organism Escherichia coli has been the subject of intense study for decades, the full complement of its RNAs is only now being examined. Here…”
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Grad-seq shines light on unrecognized RNA and protein complexes in the model bacterium Escherichia coli by Hör, Jens, Di Giorgio, Silvia, Gerovac, Milan, Venturini, Elisa, Förstner, Konrad U, Vogel, Jörg

“…Abstract Stable protein complexes, including those formed with RNA, are major building blocks of every living cell. Escherichia coli has been the leading…”
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READemption-a tool for the computational analysis of deep-sequencing-based transcriptome data by Förstner, Konrad U, Vogel, Jörg, Sharma, Cynthia M

“…RNA-Seq has become a potent and widely used method to qualitatively and quantitatively study transcriptomes. To draw biological conclusions based on RNA-Seq…”
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Differential RNA-seq of Vibrio cholerae identifies the VqmR small RNA as a regulator of biofilm formation by Papenfort, Kai, Förstner, Konrad U, Cong, Jian-Ping, Sharma, Cynthia M, Bassler, Bonnie L

“…Significance To our knowledge, this work describes the first genome-wide annotation of transcriptional start sites in Vibrio cholerae and the discovery and…”
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CoLoC-seq probes the global topology of organelle transcriptomes by Jeandard, Damien, Smirnova, Anna, Fasemore, Akinyemi Mandela, Coudray, Léna, Entelis, Nina, Förstner, Konrad U, Tarassov, Ivan, Smirnov, Alexandre

“…Proper RNA localisation is essential for physiological gene expression. Various kinds of genome-wide approaches permit to comprehensively profile subcellular…”
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Characterization of the transcriptome of Haloferax volcanii, grown under four different conditions, with mixed RNA-Seq by Laass, Sebastian, Monzon, Vivian A, Kliemt, Jana, Hammelmann, Matthias, Pfeiffer, Friedhelm, Förstner, Konrad U, Soppa, Jörg

“…Haloferax volcanii is a well-established model species for haloarchaea. Small scale RNomics and bioinformatics predictions were used to identify small…”
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Primary transcriptome map of the hyperthermophilic archaeon Thermococcus kodakarensis by Jäger, Dominik, Förstner, Konrad U, Sharma, Cynthia M, Santangelo, Thomas J, Reeve, John N

“…Prokaryotes have relatively small genomes, densely-packed with protein-encoding sequences. RNA sequencing has, however, revealed surprisingly complex…”
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GT‐rich promoters can drive RNA pol II transcription and deposition of H2A.Z in African trypanosomes by Wedel, Carolin, Förstner, Konrad U, Derr, Ramona, Siegel, T Nicolai

“…Genome‐wide transcription studies are revealing an increasing number of “dispersed promoters” that, unlike “focused promoters”, lack well‐conserved sequence…”
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Functional high-throughput screening identifies the miR-15 microRNA family as cellular restriction factors for Salmonella infection by Maudet, Claire, Mano, Miguel, Sunkavalli, Ushasree, Sharan, Malvika, Giacca, Mauro, Förstner, Konrad U., Eulalio, Ana

“…Increasing evidence suggests an important role for miRNAs in the molecular interplay between bacterial pathogens and host cells. Here we perform a fluorescence…”
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Gene autoregulation by 3' UTR-derived bacterial small RNAs by Hoyos, Mona, Huber, Michaela, Förstner, Konrad U, Papenfort, Kai

“…Negative feedback regulation, that is the ability of a gene to repress its own synthesis, is the most abundant regulatory motif known to biology. Frequently…”
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Cytosolic Sensing of Intracellular Staphylococcus aureus by Mast Cells Elicits a Type I IFN Response That Enhances Cell-Autonomous Immunity by Goldmann, Oliver, Sauerwein, Till, Molinari, Gabriella, Rohde, Manfred, Förstner, Konrad U, Medina, Eva

“…Strategically located at mucosal sites, mast cells are instrumental in sensing invading pathogens and modulating the quality of the ensuing immune responses…”
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Insights into Microalga and Bacteria Interactions of Selected Phycosphere Biofilms Using Metagenomic, Transcriptomic, and Proteomic Approaches by Krohn-Molt, Ines, Alawi, Malik, Förstner, Konrad U, Wiegandt, Alena, Burkhardt, Lia, Indenbirken, Daniela, Thieß, Melanie, Grundhoff, Adam, Kehr, Julia, Tholey, Andreas, Streit, Wolfgang R

“…Microalga are of high relevance for the global carbon cycling and it is well-known that they are associated with a microbiota. However, it remains unclear, if…”
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Genome organization and DNA accessibility control antigenic variation in trypanosomes by Müller, Laura S. M., Cosentino, Raúl O., Förstner, Konrad U., Guizetti, Julien, Wedel, Carolin, Kaplan, Noam, Janzen, Christian J., Arampatzi, Panagiota, Vogel, Jörg, Steinbiss, Sascha, Otto, Thomas D., Saliba, Antoine-Emmanuel, Sebra, Robert P., Siegel, T. Nicolai

“…Many evolutionarily distant pathogenic organisms have evolved similar survival strategies to evade the immune responses of their hosts. These include antigenic…”
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The Primary Transcriptome of Barley Chloroplasts: Numerous Noncoding RNAs and the Dominating Role of the Plastid-Encoded RNA Polymerase by Zhelyazkova, Petya, Sharma, Cynthia M., Förstner, Konrad U., Liere, Karsten, Vogel, Jörg, Börner, Thomas

“…Gene expression in plastids of higher plants is dependent on two different transcription machineries, a plastid-encoded bacterial-type RNA polymerase (PEP) and…”
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The small DUF1127 protein CcaF1 from Rhodobacter sphaeroides is an RNA-binding protein involved in sRNA maturation and RNA turnover by Grützner, Julian, Billenkamp, Fabian, Spanka, Daniel-Timon, Rick, Tim, Monzon, Vivian, Förstner, Konrad U, Klug, Gabriele

“…Abstract Many different protein domains are conserved among numerous species, but their function remains obscure. Proteins with DUF1127 domains number >17 000…”
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