Search Results - "Földes, Gábor"
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Application of Human Induced Pluripotent Stem Cell Technology for Cardiovascular Regenerative Pharmacology
Published in Methods in molecular biology (Clifton, N.J.) (2022)“…Cardiovascular diseases are one of the leading causes of mortality in the western world. Myocardial infarction is among the most prevalent and results in…”
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New Modalities of 3D Pluripotent Stem Cell-Based Assays in Cardiovascular Toxicity
Published in Frontiers in pharmacology (29-03-2021)“…The substantial progress of the human induced pluripotent stem cell (hiPSC) technologies over the last decade has provided us with new opportunities for…”
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Generation and Analysis of Pluripotent Stem Cell-Derived Cardiomyocytes and Endothelial Cells for High Content Screening Purposes
Published in Methods in molecular biology (Clifton, N.J.) (2020)“…Human-induced pluripotent stem cells (hiPSCs) and their differentiated derivatives became a new, promising source for in vitro screening techniques. Cell lines…”
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Monitoring correlates of SARS-CoV-2 infection in cell culture using a two-photon-active calcium-sensitive dye
Published in Cellular & molecular biology letters (19-07-2024)“…The organism-wide effects of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral infection are well studied, but little is known about the…”
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Generation of iPSC lines from peripheral blood mononuclear cells of identical twins both suffering from type 2 diabetes mellitus and one of them additionally diagnosed with atherosclerosis
Published in Stem cell research (01-12-2020)“…Here we describe the generation of induced pluripotent stem cell (iPSC) lines from peripheral blood samples of identical twin sisters with type 2 diabetes…”
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Modulation of human embryonic stem cell-derived cardiomyocyte growth: A testbed for studying human cardiac hypertrophy?
Published in Journal of molecular and cellular cardiology (01-02-2011)“…Abstract Human embryonic stem cell-derived cardiomyocytes (hESC-CM) are being developed for tissue repair and as a model system for cardiac physiology and…”
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ESC Heart Failure increases its impact factor
Published in ESC Heart Failure (01-12-2020)“…The journal's main topics include basic and translational research questions regarding the pathophysiology, electrophysiology, and biology of heart failure;…”
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3D culturing of human pluripotent stem cells-derived endothelial cells for vascular regeneration
Published in Theranostics (01-01-2022)“…Human induced pluripotent stem cell-derived endothelial cells can be candidates for engineering therapeutic vascular grafts. Here, we studied the role of…”
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Nuclear pore rearrangements and nuclear trafficking in cardiomyocytes from rat and human failing hearts
Published in Cardiovascular research (01-01-2015)“…During cardiac hypertrophy, cardiomyocytes (CMs) increase in the size and expression of cytoskeletal proteins while reactivating a foetal gene programme. The…”
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Innate immunity in human embryonic stem cells: comparison with adult human endothelial cells
Published in PloS one (05-05-2010)“…Treatment of human disease with human embryonic stem cell (hESC)-derived cells is now close to reality, but little is known of their responses to physiological…”
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Apelin, the Novel Endogenous Ligand of the Orphan Receptor APJ, Regulates Cardiac Contractility
Published in Circulation research (06-09-2002)“…ABSTRACT—The orphan receptor APJ and its recently identified endogenous ligand, apelin, exhibit high levels of mRNA expression in the heart. However, the…”
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Prevention of liver cancer cachexia-induced cardiac wasting and heart failure
Published in European heart journal (01-04-2014)“…Symptoms of cancer cachexia (CC) include fatigue, shortness of breath, and impaired exercise capacity, which are also hallmark symptoms of heart failure (HF)…”
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Atorvastatin Modulates Th1/Th2 Response in Patients With Chronic Heart Failure
Published in Journal of cardiac failure (01-08-2009)Get full text
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Modeling Transposition of the Great Arteries with Patient-Specific Induced Pluripotent Stem Cells
Published in International journal of molecular sciences (09-12-2021)“…The dextro-transposition of the great arteries (d-TGA) is one of the most common congenital heart diseases. To identify biological processes that could be…”
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Factors Derived from Adrenals Are Required for Activation of Cardiac Gene Expression in Angiotensin II-Induced Hypertension
Published in Endocrinology (Philadelphia) (01-10-2001)“…The mechanisms mediating the activation of cardiac gene expression during pressure overload are not fully understood. We examined whether angiotensin…”
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Three Huntington's Disease Specific Mutation-Carrying Human Embryonic Stem Cell Lines Have Stable Number of CAG Repeats upon In Vitro Differentiation into Cardiomyocytes
Published in PloS one (20-05-2015)“…Huntington disease (HD; OMIM 143100), a progressive neurodegenerative disorder, is caused by an expanded trinucleotide CAG (polyQ) motif in the HTT gene…”
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Fluvastatin reduces increased blood monocyte Toll-like receptor 4 expression in whole blood from patients with chronic heart failure
Published in International journal of cardiology (20-02-2008)“…Abstract Background Innate immune activation mediated by myocardial Toll-like receptors (TLRs) is involved in cardiovascular disease. The function and role of…”
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It Takes Two: Endothelial-Perivascular Cell Cross-Talk in Vascular Development and Disease
Published in Frontiers in cardiovascular medicine (30-10-2018)“…The formation of new blood vessels is a crucial step in the development of any new tissue both during embryogenesis and models as without sufficient perfusion…”
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Aberrant α-Adrenergic Hypertrophic Response in Cardiomyocytes from Human Induced Pluripotent Cells
Published in Stem cell reports (11-11-2014)“…Cardiomyocytes from human embryonic stem cells (hESC-CMs) and induced pluripotent stem cells (hiPSC-CMs) represent new models for drug discovery. Although…”
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Evidence for a functional role of angiotensin II type 2 receptor in the cardiac hypertrophic process in vivo in the rat heart
Published in Circulation (New York, N.Y.) (11-11-2003)“…The precise function of angiotensin II type 2 receptor (AT2-R) in the mammalian heart in vivo is unknown. Here, we investigated the role of AT2-R in cardiac…”
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