Search Results - "Fæste, Christiane Kruse"
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Prediction of deoxynivalenol toxicokinetics in humans by in vitro-to-in vivo extrapolation and allometric scaling of in vivo animal data
Published in Archives of toxicology (01-07-2018)“…Deoxynivalenol (DON) is the most prevalent mycotoxin in cereals worldwide. It can cause adverse health effects in humans and animals, and maximum levels in…”
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Biotransformation of the mycotoxin enniatin B1 in pigs: A comparative in vitro and in vivo approach
Published in Food and chemical toxicology (01-07-2017)“…Enniatins (ENNs) are hexadepsipeptidic mycotoxins produced by Fusarium species. They occur in mg/kg levels in grain from Northern climate areas. Major ENNs…”
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Transfer of Deoxynivalenol (DON) through Placenta, Colostrum and Milk from Sows to Their Offspring during Late Gestation and Lactation
Published in Toxins (04-12-2018)“…Deoxynivalenol (DON) contamination of feed may result in reduced growth, feed refusal, immunosuppression, and health problems in swine. Piglets can be exposed…”
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Deoxynivalenol Exposure in Norway, Risk Assessments for Different Human Age Groups
Published in Toxins (04-02-2017)“…Deoxynivalenol (DON) is the most common mycotoxin in Norwegian cereals, and DON is detected in most samples of crude cereal grain and cereal food commodities…”
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Identification and cross-species comparison of in vitro phase I brevetoxin (BTX-2) metabolites in northern Gulf of Mexico fish and human liver microsomes by UHPLC-HRMS(/MS)
Published in Toxicon X (01-09-2023)“…Brevetoxins (BTX) are a group of marine neurotoxins produced by the harmful alga Karenia brevis. Numerous studies have shown that BTX are rapidly accumulated…”
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Metabolomics and Multi-Omics Determination of Potential Plasma Biomarkers in PRV-1-Infected Atlantic Salmon
Published in Metabolites (02-07-2024)“…Metabolomic analysis has been explored to search for disease biomarkers in humans for some time. The application to animal species, including fish, however, is…”
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Development and Validation of a Liquid Chromatography High-Resolution Mass Spectrometry Method for the Simultaneous Determination of Mycotoxins and Phytoestrogens in Plant-Based Fish Feed and Exposed Fish
Published in Toxins (13-04-2019)“…New protein sources in fish feed require the assessment of the carry-over potential of contaminants and anti-nutrients from feed ingredients into the fish, and…”
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Impact of Plasma-Activated Water Treatment on Quality and Shelf-Life of Fresh Spinach Leaves Evaluated by Comprehensive Metabolomic Analysis
Published in Foods (09-12-2021)“…Fresh baby spinach leaves are popular in salads and are sold as chilled and plastic-packed products. They are of high nutritional value but very perishable due…”
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In Vitro Glucuronidation of Caribbean Ciguatoxins in Fish: First Report of Conjugative Ciguatoxin Metabolites
Published in Chemical research in toxicology (16-08-2021)“…Ciguatoxins (CTX) are potent marine neurotoxins, which can bioaccumulate in seafood, causing a severe and prevalent human illness known as ciguatera poisoning…”
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Potential plasma biomarkers for the onset of heart and skeletal muscle inflammation from Piscine orthoreovirus-1 infection in Atlantic salmon (Salmo salar)
Published in Aquaculture (15-09-2024)“…Biomarkers that give quantifiable information about disease development are valuable diagnostic indicators providing opportunities to thwart adverse outcomes…”
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Metabolomics workflow for quality control of differently-processed pre-cooked chicken fillets
Published in Food chemistry (15-02-2022)“…•Untargeted metabolomics is valid tool to access effect of food preservation methods.•Stringent chemometric workflow helps avoiding misinterpretations.•Vacuum…”
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Biotransformation of phytoestrogens from soy in enzymatically characterized liver microsomes and primary hepatocytes of Atlantic salmon
Published in Ecotoxicology and environmental safety (01-07-2020)“…Efficient aquaculture is depending on sustainable protein sources. The shortage in marine raw materials has initiated a shift to “green aquafeeds” based on…”
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Enzyme-Assisted Synthesis and Structural Characterization of the 3‑, 8‑, and 15-Glucuronides of Deoxynivalenol
Published in Journal of agricultural and food chemistry (27-02-2013)“…4-Deoxynivalenol is one of the most prevalent mycotoxins in grain-based food and feed products worldwide. Conjugation of deoxynivalenol to glucuronic acid and…”
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Development of liquid chromatography-tandem mass spectrometry methods for the quantitation of Anisakis simplex proteins in fish
Published in Journal of Chromatography A (05-02-2016)“…•Identification of unique Anisakis simplex reporter peptides (URPs).•nLC-nESI-Orbitrap-MS/MS method for A. simplex protein semi-quantitation in fish…”
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A ranking method of chemical substances in foods for prioritisation of monitoring, based on health risk and knowledge gaps
Published in Food research international (01-11-2020)“…[Display omitted] •Occurrence data for chemical compounds in foods are critical for food safety.•Linear semi-quantitative method to rank chemicals in foods for…”
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Hazard characterization of Alternaria toxins to identify data gaps and improve risk assessment for human health
Published in Archives of toxicology (01-02-2024)“…Fungi of the genus Alternaria are ubiquitous plant pathogens and saprophytes which are able to grow under varying temperature and moisture conditions as well…”
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Effects and biotransformation of the mycotoxin deoxynivalenol in growing pigs fed with naturally contaminated pelleted grains with and without the addition of Coriobacteriaceum DSM 11798
Published in Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment (03-07-2018)“…Deoxynivalenol (DON) is one of the most prevalent Fusarium mycotoxins in grain and can cause economic losses in pig farming due to reduced feed consumption and…”
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Neurotoxic Potential of Deoxynivalenol in Murine Brain Cell Lines and Primary Hippocampal Cultures
Published in Toxins (01-01-2022)“…Chronic exposure to the mycotoxin deoxynivalenol (DON) from grain-based food and feed affects human and animal health. Known consequences include…”
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Tissue distribution and elimination of deoxynivalenol and ochratoxin A in dietary-exposed Atlantic salmon (Salmo salar)
Published in Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment (03-07-2017)“…Post-smolt Atlantic salmon (Salmo salar) were fed standard feed with added 2 or 6 mg kg -1 pure deoxynivalenol (DON), 0.8 or 2.4 mg kg -1 pure ochratoxin A…”
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Atlantic Salmon Gill Epithelial Cell Line (ASG-10) as a Suitable Model for Xenobiotic Biotransformation
Published in Metabolites (01-06-2023)“…Fish are exposed to xenobiotics in the water. Uptake occurs mainly through the gills, which function as an exchange point with the environment. The gills'…”
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