Search Results - "Färber, Katrin"

Functional role of calcium signals for microglial function by Färber, Katrin, Kettenmann, Helmut

“…In this review we summarize mechanisms of Ca2+ signaling in microglial cells and the impact of Ca2+ signaling and Ca2+ levels on microglial function. So far,…”
Get full text

WNT signaling in activated microglia is proinflammatory by Halleskog, Carina, Mulder, Jan, Dahlström, Jenny, Mackie, Ken, Hortobágyi, Tibor, Tanila, Heikki, Kumar Puli, Lakshman, Färber, Katrin, Harkany, Tibor, Schulte, Gunnar

“…Microglia activation is central to the neuroinflammation associated with neurological and neurodegenerative diseases, particularly because activated microglia…”
Get full text

A1 adenosine receptors in microglia control glioblastoma-host interaction by SYNOWITZ, Michael, GLASS, Rainer, KETTENMANN, Helmut, FÄRBER, Katrin, MARKOVIC, Darko, KRONENBERG, Golo, HERRMANN, Ken, SCHNERMANN, Juergen, NOLTE, Christiane, VAN ROOIJEN, Nico, KIWIT, Juergen

“…We report that experimental glioblastoma grow more vigorously in A(1) adenosine receptor (A(1)AR)-deficient mice associated with a strong accumulation of…”
Get full text

Transmitter- and hormone-activated Ca2+ responses in adult microglia/brain macrophages in situ recorded after viral transduction of a recombinant Ca2+ sensor by Seifert, Stefanie, Pannell, Maria, Uckert, Wolfgang, Färber, Katrin, Kettenmann, Helmut

“…Abstract In vitro studies show that microglia, the resident immune cells of the brain, express neurotransmitter and neuropeptide receptors which are linked to…”
Get full text

The ectonucleotidase cd39/ENTPDase1 modulates purinergic-mediated microglial migration by Färber, Katrin, Markworth, Sören, Pannasch, Ulrike, Nolte, Christiane, Prinz, Vincent, Kronenberg, Golo, Gertz, Karen, Endres, Matthias, Bechmann, Ingo, Enjyoji, Keiichi, Robson, Simon C., Kettenmann, Helmut

“…Microglia is activated by brain injury. They migrate in response to ATP and although adenosine alone has no effect on wild type microglial migration, we show…”
Get full text

Endogenous purinergic signaling is required for osmotic volume regulation of retinal glial cells by Wurm, Antje, Lipp, Stephan, Pannicke, Thomas, Linnertz, Regina, Krügel, Ute, Schulz, Angela, Färber, Katrin, Zahn, Dirk, Grosse, Johannes, Wiedemann, Peter, Chen, Ju, Schöneberg, Torsten, Illes, Peter, Reichenbach, Andreas, Bringmann, Andreas

“…J. Neurochem. (2010) 112, 1261-1272. Intense neuronal activity in the sensory retina is associated with a volume increase of neuronal cells (Uckermann et al.,…”
Get full text

Purinergic receptors on microglial cells: functional expression in acute brain slices and modulation of microglial activation in vitro by Boucsein, Clemens, Zacharias, Robert, Färber, Katrin, Pavlovic, Sanja, Hanisch, Uwe-Karsten, Kettenmann, Helmut

“…Microglial cells are the pathologic sensors in the brain. ATP released from damaged cells is a candidate for signalling neural injury to microglia. Moreover,…”
Get full text

C1q, the recognition subcomponent of the classical pathway of complement, drives microglial activation by Färber, Katrin, Cheung, Giselle, Mitchell, Daniel, Wallis, Russell, Weihe, Eberhard, Schwaeble, Wilhelm, Kettenmann, Helmut

“…Microglia, central nervous system (CNS) resident phagocytic cells, persistently police the integrity of CNS tissue and respond to any kind of damage or…”
Get full text

Acute neuroprotection by pioglitazone after mild brain ischemia without effect on long-term outcome by Ji, Shengbo, Kronenberg, Golo, Balkaya, Mustafa, Färber, Katrin, Gertz, Karen, Kettenmann, Helmut, Endres, Matthias

“…Peroxisome proliferator-activated receptor-gamma (PPAR-γ) agonists (thiazolidinediones) have anti-inflammatory effects and improve endothelium function. Here,…”
Get full text

Physiology of microglial cells by Färber, Katrin, Kettenmann, Helmut

“…Microglial cells in culture and in situ express a defined pattern of K + channels, which is distinct from that of other glial cells and neurons. This pattern…”
Get full text

Purinergic signaling and microglia by Färber, Katrin, Kettenmann, Helmut

“…Microglial cells are considered as the pathologic sensors of the brain. In this paper, we review mechanisms of purinergic signaling in microglia. As ATP is not…”
Get full text

Dopamine and noradrenaline control distinct functions in rodent microglial cells by Färber, Katrin, Pannasch, Ulrike, Kettenmann, Helmut

“…Microglial cells are the immune-competent elements of the brain. They not only express receptors for chemokines and cytokines but also for neurotransmitters…”
Get full text

An α5β1 integrin inhibitor attenuates glioma growth by Färber, Katrin, Synowitz, Michael, Zahn, Grit, Vossmeyer, Dörte, Stragies, Roland, van Rooijen, Nico, Kettenmann, Helmut

“…Integrins are heterodimeric transmembrane proteins, which mediate cell–cell and cell–extracellular matrix (ECM) interaction. We show, that an inhibitor of…”
Get full text

Functional role of calcium signals for microglial function : Calcium signaling in invertebrate glial cells by FÄRBER, Katrin, KETTENMANN, Helmut

Get full text

Bradykinin-Induced Microglial Migration Mediated by B1-Bradykinin Receptors Depends on Ca2+ Influx via Reverse-Mode Activity of the Na+/Ca2+ Exchanger by Ifuku, Masataka, Farber, Katrin, Okuno, Yuko, Yamakawa, Yukiko, Miyamoto, Taiki, Nolte, Christiane, Merrino, Vanessa F, Kita, Satomi, Iwamoto, Takahiro, Komuro, Issei, Wang, Bing, Cheung, Giselle, Ishikawa, Eiichi, Ooboshi, Hiroaki, Bader, Michael, Wada, Keiji, Kettenmann, Helmut, Noda, Mami

“…Bradykinin (BK) is produced and acts at the site of injury and inflammation. In the CNS, migration of microglia toward the lesion site plays an important role…”
Get full text

Microglia express GABA(B) receptors to modulate interleukin release by Kuhn, Susanne A, van Landeghem, Frank K H, Zacharias, Robert, Färber, Katrin, Rappert, Angelika, Pavlovic, Sanja, Hoffmann, Anja, Nolte, Christiane, Kettenmann, Helmut

“…gamma-Aminobutyric acid (GABA) can act as a neuroprotective agent besides its well-established role as the main inhibitory neurotransmitter in the CNS. Here we…”
Get full text

Involvement of A1 adenosine receptors in osmotic volume regulation of retinal glial cells in mice by Wurm, Antje, Lipp, Stephan, Pannicke, Thomas, Linnertz, Regina, Färber, Katrin, Wiedemann, Peter, Reichenbach, Andreas, Bringmann, Andreas

Get full text

Microglia express GABAB receptors to modulate interleukin release by Kuhn, SA, van Landeghem, FK, Zacharias, R, Farber, K, Rappert, A, Pavlovic, S, Hoffmann, A, Nolte, C, Kettenmann, H

“…gamma -Aminobutyric acid (GABA) can act as a neuroprotective agent besides its well-established role as the main inhibitory neurotransmitter in the CNS. Here…”
Get full text

WNT signaling in activated microglia is pro-inflammatory: WNT/β-catenin signaling in microglia by Halleskog, Carina, Mulder, Jan, Dahlström, Jenny, Mackie, Ken, Hortobágyi, Tibor, Tanila, Heikki, Puli, Lakshman Kumar, Färber, Katrin, Harkany, Tibor, Schulte, Gunnar

“…Microglia activation is central to the neuroinflammation associated with neurological and neurodegenerative diseases, particularly since activated microglia…”
Get full text

The potassium channels Kv1.5 and Kv1.3 modulate distinct functions of microglia by Pannasch, Ulrike, Färber, Katrin, Nolte, Christiane, Blonski, Mary, Yan Chiu, Shing, Messing, Albee, Kettenmann, Helmut

“…Activation of microglia by LPS leads to an induction of cytokine and NO release, reduced proliferation and increased outward K + conductance, the latter…”
Get full text