Search Results - "Fällmar, Helena"
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Mutagenesis and Computational Modeling of Human G‑Protein-Coupled Receptor Y2 for Neuropeptide Y and Peptide YY
Published in Biochemistry (Easton) (12-11-2013)“…Neuropeptide Y and peptide YY receptor type 2 (Y2) is involved in appetite regulation and several other physiological processes. We have investigated the…”
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Neuropeptide Y/peptide YY receptor Y2 duplicate in zebrafish with unique introns displays distinct peptide binding properties
Published in Comparative Biochemistry and Physiology - Part B (01-12-2011)“…The neuropeptide Y-family peptides and receptors are involved in a broad range of functions including appetite regulation. Both the peptide genes and the…”
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Identification of positions in the human neuropeptide Y/peptide YY receptor Y2 that contribute to pharmacological differences between receptor subtypes
Published in Neuropeptides (Edinburgh) (01-08-2011)“…Abstract The members of the neuropeptide Y (NPY) family are key players in food-intake regulation. In humans this family consists of NPY, peptide YY (PYY) and…”
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Mutagenesis of human neuropeptide Y/peptide YY receptor Y2 reveals additional differences to Y1 in interactions with highly conserved ligand positions
Published in Regulatory peptides (09-08-2010)“…Neuropeptide Y (NPY) and peptide YY (PYY) share ∼ 70% of their 36 amino acids and bind to the same three human receptor subtypes, Y1, Y2 and Y5, even though…”
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