Search Results - "Ezeonwuka, Chinelo"
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Brain region-specific expression of MeCP2 isoforms correlates with DNA methylation within Mecp2 regulatory elements
Published in PloS one (03-03-2014)“…MeCP2 is a critical epigenetic regulator in brain and its abnormal expression or compromised function leads to a spectrum of neurological disorders including…”
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Evolution of Outbreak-Causing Carbapenem-Resistant Klebsiella pneumoniae ST258 at a Tertiary Care Hospital over 8 Years
Published in mBio (03-09-2019)“…Carbapenem-resistant (CRKP) strains belonging to sequence type 258 (ST258) are frequent causes of hospital-associated outbreaks and are a major contributor to…”
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3
Novel MeCP2 isoform-specific antibody reveals the endogenous MeCP2E1 expression in murine brain, primary neurons and astrocytes
Published in PloS one (19-11-2012)“…Rett Syndrome (RTT) is a severe neurological disorder in young females, and is caused by mutations in the X-linked MECP2 gene. MECP2/Mecp2 gene encodes for two…”
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Use of online tools for antimicrobial resistance prediction by whole-genome sequencing in methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococci (VRE)
Published in Journal of global antimicrobial resistance. (01-12-2019)“…•Whole-genome sequencing can rapidly deliver genetic antimicrobial resistance (AMR) data.•Using genetic AMR data, phenotypic resistance can be predicted.•This…”
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5
Genomic Diversity of Hospital-Acquired Infections Revealed through Prospective Whole-Genome Sequencing-Based Surveillance
Published in mSystems (28-06-2022)“…Healthcare-associated infections (HAIs) cause mortality, morbidity, and waste of health care resources. HAIs are also an important driver of antimicrobial…”
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6
MeCP2-Related Diseases and Animal Models
Published in Diseases (27-01-2014)“…The role of epigenetics in human disease has become an area of increased research interest. Collaborative efforts from scientists and clinicians have led to a…”
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Journal Article Book Review -
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Draft Genome Sequences of Four Hospital-Associated Pseudomonas putida Isolates
Published in Genome announcements (Washington, DC) (29-09-2016)“…We present here the draft genome sequences of four Pseudomonas putida isolates belonging to a single clone suspected for nosocomial transmission between…”
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Whole-Genome Sequencing Surveillance and Machine Learning of the Electronic Health Record for Enhanced Healthcare Outbreak Detection
Published in Clinical infectious diseases (31-08-2022)“…Most hospitals use traditional infection prevention (IP) methods for outbreak detection. We developed the Enhanced Detection System for Healthcare-Associated…”
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Outbreak of Vancomycin-resistant Enterococcus faecium in Interventional Radiology: Detection Through Whole-genome Sequencing-based Surveillance
Published in Clinical infectious diseases (23-05-2020)“…Abstract Background Vancomycin-resistant enterococci (VRE) are a major cause of hospital-acquired infections. The risk of infection from interventional…”
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Transmission Dynamics and Microevolution of Neisseria meningitidi s During Carriage and Invasive Disease in High School Students in Georgia and Maryland, 2006–2007
Published in The Journal of infectious diseases (15-06-2021)“…Abstract Background The mechanisms by which Neisseria meningitidis cause persistent human carriage and transition from carriage to invasive disease have not…”
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Outbreak of Pseudomonas aeruginosa Infections from a Contaminated Gastroscope Detected by Whole Genome Sequencing Surveillance
Published in Clinical infectious diseases (02-08-2021)“…Traditional methods of outbreak investigations utilize reactive whole genome sequencing (WGS) to confirm or refute the outbreak. We have implemented WGS…”
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Transmission Dynamics and Microevolution of Neisseria meningitidis During Carriage and Invasive Disease in High School Students in Georgia and Maryland, 2006–2007
Published in The Journal of infectious diseases (15-06-2021)“…Abstract Background The mechanisms by which Neisseria meningitidis cause persistent human carriage and transition from carriage to invasive disease have not…”
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13
Clostridioides difficile: a potential source of NpmA in the clinical environment
Published in Journal of antimicrobial chemotherapy (01-02-2019)Get full text
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14
Neisseria meningitidis disease-associated clones in Amazonas State, Brazil
Published in Infectious diseases (London, England) (02-09-2018)“…Background: The aim of this study is to describe the molecular epidemiology of Neisseria meningitidis invasive disease before the introduction of serogroup C…”
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The use of Online Tools for Antimicrobial Resistance Prediction by Whole Genome Sequencing in MRSA and VRE
Published in Journal of global antimicrobial resistance. (18-04-2019)Get full text
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Brain Region-Specific Expression of MeCP2 Isoforms Correlates with DNA Methylation within Mecp2 Regulatory Elements: e90645
Published in PloS one (01-03-2014)“…MeCP2 is a critical epigenetic regulator in brain and its abnormal expression or compromised function leads to a spectrum of neurological disorders including…”
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Journal Article