Search Results - "Ezekowitz, A. B."

Phylogenetic Perspectives in Innate Immunity by Hoffmann, Jules A., Kafatos, Fotis C., Janeway, Charles A., Ezekowitz, R. A. B.

“…The concept of innate immunity refers to the first-line host defense that serves to limit infection in the early hours after exposure to microorganisms. Recent…”
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systems biology analysis of the Drosophila phagosome by Stuart, L.M, Boulais, J, Charriere, G.M, Hennessy, E.J, Brunet, S, Jutras, I, Goyette, G, Rondeau, C, Letarte, S, Huang, H

“…Phagocytes have a critical function in remodelling tissues during embryogenesis and thereafter are central effectors of immune defence. During phagocytosis,…”
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Characterization and Quantification of Mouse Mannan‐Binding Lectins (MBL‐A and MBL‐C) and Study of Acute Phase Responses by Liu, H., Jensen, L., Hansen, S., Petersen, S. V., Takahashi, K., Ezekowitz, A. B., Hansen, F. D., Jensenius, J. C., Thiel, S.

“…Rat monoclonal antibodies (MoAbs) against mouse mannan‐binding lectin (MBL)‐A and MBL‐C were generated and assays for MBL‐A and MBL‐C were constructed. This…”
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Uptake of Pneumocystis carinii mediated by the macrophage mannose receptor by Ezekowitz, R. A. B, Williams, D. J, Koziel, H, Armstrong, M. Y. K, Warner, A, Richards, F. F, Rose, R. M

“…Human exposure to Pneumocystis carinii is common but, in the absence of acquired or genetic dysfunction of either cellular or humoral immunity, exposure rarely…”
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The Gly-54-->Asp allelic form of human mannose-binding protein (MBP) fails to bind MBP-associated serine protease by Matsushita, M, Ezekowitz, R A, Fujita, T

“…The human mannose-binding protein (MBP) is a pattern recognition molecule that appears to play a role in initial host defence. MBP activates the complement…”
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Restriction of interferon γ responsiveness and basal expression of the myeloid human FcγR1b gene is mediated by a functional PU.1 site and a transcription initiator consensus by EICHBAUM, Q. G, IYER, R, RAVEH, D. P, MATHIEU, C, EZEKOWITZ, R. A. B

“…The restricted expression of the human Fc gamma R1b gene to myeloid cells is likely to be regulated by a combination of transcription factors that may not be…”
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Characterization of murine mannose-binding protein genes Mbl1 and Mbl2 reveals features common to other collectin genes by Sastry, R, Wang, J S, Brown, D C, Ezekowitz, R A, Tauber, A I, Sastry, K N

“…Mannose-binding protein (MBP) is a member of a family of collagenous lectins (collectins), which are believed to play an important role in first-line host…”
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The structure and function of vertebrate mannose lectin-like proteins by Ezekowitz, R A, Stahl, P D

“…Sugar-specific recognition is now well established as an important determinant of cell-cell interactions and host defence mechanisms. Macrophages, in…”
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Distinct and overlapping functions of allelic forms of human mannose binding protein by Super, M, Gillies, S. D, Foley, S, Sastry, K, Schweinle, J.-E, Silverman, V. J, Ezekowitz, R. A. B

“…Human mannose binding protein (MBP) is a C-type serum lectin involved in first-line host defense against a variety of bacterial, fungal and viral pathogens…”
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Complement-dependent neutralization of influenza virus by a serum mannose-binding lectin by Anders, E. Margot, Hartley, Carol A, Reading, Patrick C, Ezekowitz, R. Alan B

“…1 Department of Microbiology, University of Melbourne, Parkville, Victoria 3052, Australia and 2 Division of Hematology/Oncology, Children's Hospital and…”
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Mannose-binding protein B allele confers protection against tuberculous meningitis by Hoal-Van Helden, E G, Epstein, J, Victor, T C, Hon, D, Lewis, L A, Beyers, N, Zurakowski, D, Ezekowitz, A B, Van Helden, P D

“…Inhalation is the principal mode of entry for Mycobacterium tuberculosis in humans. Primary infection is usually restricted to the lungs and contiguous lymph…”
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Definition of interferon γ-response elements in a novel human Fcγ receptor gene (FcγRIb) and characterization of the gene structure by BENECH, P. D, SASTRY, K, IYER, R. R, EICHBAUM, Q. G, RAVEH, D. P, EZEKOWITZ, R. A. B

“…The human Fc gamma RI (CD64) is a high affinity receptor for the Fc portion of immunoglobulin (Ig), and its constitutively low expression on the cell surface…”
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The murine mannose-binding protein genes (Mbl 1 and Mbl 2) localize to chromosomes 14 and 19 by White, R A, Dowler, L L, Adkison, L R, Ezekowitz, R A, Sastry, K N

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Requirement for croquemort in phagocytosis of apoptotic cells in Drosophila by Franc, N.C, Heitzler, P, Ezekowitz, R.A.B, White, K

“…Macrophages in the Drosophila embryo are responsible for the phagocytosis of apoptotic cells and are competent to engulf bacteria. Croquemort (CRQ) is a…”
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Characterization of the Murine Macrophage Mannose Receptor: Demonstration That the Downregulation of Receptor Expression Mediated by Interferon-γ Occurs at the Level of Transcription by Harris, Neil, Super, Michael, Rits, Miriam, Chang, Grace, Ezekowitz, R. Alan B.

“…The macrophage mannose receptor (MMR) is a 175-Kd cell-surface transmembrane glycoprotein that is expressed on tissue macrophages where it functions both to…”
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Spastic diplegia as a complication of interferon Alfa-2a treatment of hemangiomas of infancy by Barlow, Charles F., Priebe, Cedric J., Mulliken, John B., Barnes, Patrick D., Mac Donald, Dorothy, Folkman, Judah, Ezekowitz, R.Alan B.

“…We report the development of spastic diplegia in infants during the course of interferon Alfa-2a (IFN) therapy for potentially life-endangering hemangiomas…”
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Interferon Alfa-2a Therapy for Life-Threatening Hemangiomas of Infancy by Ezekowitz, R. Alan B, Mulliken, John B, Folkman, Judah

“…HEMANGIOMA of infancy is an angiomatous disorder characterized by the proliferation of capillary endothelium, with multilamination of the basement membrane 1 ,…”
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Cerebral vasculopathy and neurologic sequelae in infants with cervicofacial hemangioma: report of eight patients by Burrows, P E, Robertson, R L, Mulliken, J B, Beardsley, D S, Chaloupka, J C, Ezekowitz, R A, Scott, R M

“…To determine the association of cerebral arterial anomalies and progressive cerebral arterial occlusive disease in infants with facial hemangiomas. The cases…”
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Molecular characterization of the human macrophage mannose receptor : demonstration of multiple carbohydrate recognition-like domains and phagocytosis of yeasts in cos-1 cells by EZEKOWITZ, R. A. B, SASTRY, K, BAILLY, P, WARNER, A

“…The macrophage mannose receptor is an integral membrane protein expressed on the surface of tissue macrophages. After ligation of mannose-rich glycoconjugates…”
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Hepatic vascular anomalies in infancy: A twenty-seven-year experience by Boon, Laurence M., Burrows, Patricia E., Paltiel, Harriet J., Lund, Dennis P., Ezekowitz, R.Alan B., Folkman, Judah, Mulliken, John B.

“…OBJECTIVE: Infantile hemangioma and arteriovenous malformation (AVM) of the liver have a similar presentation but a different natural history, and therefore…”
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