Search Results - "Ezanno, Hélène"
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Myristic Acid Increases Dihydroceramide Δ4-Desaturase 1 (DES1) Activity in Cultured Rat Hepatocytes
Published in Lipids (01-02-2012)“…Dihydroceramide Δ4-desaturase 1 (DES1) catalyzes the last step of the de novo ceramide biosynthesis, which consists of the introduction of a trans Δ4-double…”
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2
Endoplasmic Reticulum Stress Links Oxidative Stress to Impaired Pancreatic Beta-Cell Function Caused by Human Oxidized LDL
Published in PloS one (16-09-2016)“…Elevated plasma concentration of the pro-atherogenic oxidized low density lipoprotein cholesterol (LDL) triggers adverse effects in pancreatic beta-cells and…”
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The Map3k12 (Dlk)/JNK3 signaling pathway is required for pancreatic beta-cell proliferation during postnatal development
Published in Cellular and molecular life sciences : CMLS (01-01-2021)“…Unveiling the key pathways underlying postnatal beta-cell proliferation can be instrumental to decipher the mechanisms of beta-cell mass plasticity to…”
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Generation of an induced pluripotent stem cell (iPSC) line from a patient with maturity-onset diabetes of the young type 3 (MODY3) carrying a hepatocyte nuclear factor 1-alpha (HNF1A) mutation
Published in Stem cell research (01-05-2018)“…Heterozygous non-synonymous (p.S142F) mutation in HNF1A leads to maturity-onset diabetes of the young (MODY) type 3, which is a subtype of dominant inherited…”
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Influence of the cis-9, cis-12 and cis-15 double bond position in octadecenoic acid (18:1) isomers on the rat FADS2-catalyzed Delta 6-desaturation
Published in Chemistry and physics of lipids (01-04-2015)“…Oleic (cis9-18:1), linoleic (cis9,cis12-18:2) and alpha-linolenic (cis9,cis12,cis15-18:3) acids are well described substrates of the Delta 6-desaturase encoded…”
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Beneficial impact of a mix of dairy fat with rapeseed oil on n-6 and n-3 PUFA metabolism in the rat: A small enrichment in dietary alpha-linolenic acid greatly increases its conversion to DHA in the liver
Published in European journal of lipid science and technology (01-03-2015)“…The impact of the amount of dietary α‐linolenic acid (ALA) on its own tissue accumulation and conversion to longer n‐3 polyunsaturated fatty acids (PUFAs)…”
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JNK3 Is Required for the Cytoprotective Effect of Exendin 4
Published in Journal of diabetes research (01-01-2014)“…Preservation of beta cell against apoptosis is one of the therapeutic benefits of the glucagon-like peptide-1 (GLP1) antidiabetic mimetics for preserving the…”
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Islet Brain 1 Protects Insulin Producing Cells against Lipotoxicity
Published in Journal of diabetes research (01-01-2016)“…Chronic intake of saturated free fatty acids is associated with diabetes and may contribute to the impairment of functional beta cell mass. Mitogen activated…”
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9
Influence of the cis-9, cis-12 and cis-15 double bond position in octadecenoic acid (18:1) isomers on the rat FADS2-catalyzed Δ6-desaturation
Published in Chemistry and physics of lipids (01-04-2015)“…Oleic (cis9-18:1), linoleic (cis9,cis12-18:2) and α-linolenic (cis9,cis12,cis15-18:3) acids are well described substrates of the Δ6-desaturase encoded by the…”
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10
Fatty acid acylation of proteins: Emerging cellular functions for saturated fatty acids
Published in Nutrition clinique et métabolisme (01-02-2013)“…Fatty acid acylation of proteins corresponds to the co- or post-translational covalent linkage of a fatty acid, activated in the form of acyl-CoA, to an amino…”
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11
CAD-13 - C-Jun amino terminal kinase 3 (JNK3) contrôle la masse fonctionnelle de la cellule bêta en réponse à l’obésité
Published in Diabetes & metabolism (01-03-2017)Get full text
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C-Jun amino terminal kinase 3 (JNK3) contrôle la masse fonctionnelle de la cellule bêta en réponse à l’obésité
Published in Diabetes & metabolism (01-03-2017)Get full text
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13
Myristic Acid Increases Dihydroceramide [Delta]4-Desaturase 1 (DES1) Activity in Cultured Rat Hepatocytes
Published in Lipids (01-02-2012)“…Dihydroceramide Δ4-desaturase 1 (DES1) catalyzes the last step of the de novo ceramide biosynthesis, which consists of the introduction of a trans Δ4-double…”
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Journal Article -
14
acylation des protéines : une fonction cellulaire importante des acides gras saturés
Published in Nutrition clinique et métabolisme (2013)“…Fatty acid acylation of proteins corresponds to the co- or post-translational covalent linkage of a fatty acid, activated in the form of acyl-CoA, to an amino…”
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15
L’acylation des protéines : une fonction cellulaire importante des acides gras saturés
Published in Nutrition clinique et métabolisme (01-02-2013)“…L’acylation d’une protéine correspond à la formation co- ou post-traductionnelle d’une liaison covalente entre un acide gras activé en acyl-CoA et un résidu…”
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