Search Results - "Eyras, E."
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Prediction of m6A and m5C at single-molecule resolution reveals a transcriptome-wide co-occurrence of RNA modifications
Published in Nature communications (09-05-2024)“…The epitranscriptome embodies many new and largely unexplored functions of RNA. A significant roadblock hindering progress in epitranscriptomics is the…”
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The prognostic potential of alternative transcript isoforms across human tumors
Published in Genome medicine (17-08-2016)“…Phenotypic changes during cancer progression are associated with alterations in gene expression, which can be exploited to build molecular signatures for tumor…”
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The Ensembl genome database project
Published in Nucleic acids research (01-01-2002)“…The Ensembl (http://www.ensembl.org/) database project provides a bioinformatics framework to organise biology around the sequences of large genomes. It is a…”
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4
Ensembl 2002: accommodating comparative genomics
Published in Nucleic acids research (01-01-2003)“…The Ensembl (http://www.ensembl.org/) database project provides a bioinformatics framework to organise biology around the sequences of large genomes. It is a…”
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5
Ensembl 2004
Published in Nucleic acids research (01-01-2004)“…The Ensembl (http://www.ensembl.org/) database project provides a bioinformatics framework to organize biology around the sequences of large genomes. It is a…”
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Chromatin and alternative splicing
Published in Cold Spring Harbor Symposia on Quantitative Biology (2010)“…Alternative splicing affects more than 90% of human genes. Coupling between transcription and splicing has become crucial in the complex network underlying…”
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Multiple intersections of D-branes and M-branes
Published in Nuclear physics. B (09-06-1997)“…We give a classification of all multiple intersections of D-branes in ten dimensions and M-branes in eleven dimensions that correspond to threshold BPS bound…”
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Gauged supergravity from dimensional reduction
Published in Physics letters. B (06-11-1997)“…We perform a generalised Scherk-Schwarz reduction of the effective action of the heterotic string on T 6 to obtain a massive N = 4 supergravity theory in four…”
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Space-time-filling branes and strings with sixteen supercharges
Published in Nuclear physics. B (03-01-2000)“…We discuss branes whose world-volume dimension equals the target space-time dimension, i.e. “space-time-filling branes”. In addition to the D9-branes, there…”
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IRFinder: assessing the impact of intron retention on mammalian gene expression
Published in Genome Biology (15-03-2017)“…Intron retention (IR) occurs when an intron is transcribed into pre-mRNA and remains in the final mRNA. We have developed a program and database called…”
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The BioMart community portal: an innovative alternative to large, centralized data repositories
Published in Nucleic acids research (01-07-2015)“…The BioMart Community Portal (www.biomart.org) is a community-driven effort to provide a unified interface to biomedical databases that are distributed…”
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The ENCODE (ENCyclopedia of DNA Elements) Project
Published in Science (American Association for the Advancement of Science) (22-10-2004)“…The ENCyclopedia of DNA Elements (ENCODE) Project aims to identify all functional elements in the human genome sequence. The pilot phase of the Project is…”
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Initial sequencing and comparative analysis of the mouse genome
Published in Nature (London) (05-12-2002)“…The sequence of the mouse genome is a key informational tool for understanding the contents of the human genome and a key experimental tool for biomedical…”
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14
Kaluza-Klein Monopole and 5-brane Effective Actions
Published in Fortschritte der Physik (01-01-2000)“…We review the construction of the Kaluza‐Klein monopole of the Type IIA theory in the most general case of a massive background, as well as its relation via…”
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The Ensembl automatic gene annotation system
Published in Genome research (01-05-2004)“…As more genomes are sequenced, there is an increasing need for automated first-pass annotation which allows timely access to important genomic information. The…”
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An overview of Ensembl
Published in Genome research (01-05-2004)“…Ensembl (http://www.ensembl.org/) is a bioinformatics project to organize biological information around the sequences of large genomes. It is a comprehensive…”
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Integrative annotation of 21,037 human genes validated by full-length cDNA clones
Published in PLoS biology (01-06-2004)“…The human genome sequence defines our inherent biological potential; the realization of the biology encoded therein requires knowledge of the function of each…”
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ASTD: The Alternative Splicing and Transcript Diversity database
Published in Genomics (San Diego, Calif.) (01-03-2009)“…The Alternative Splicing and Transcript Diversity database (ASTD) gives access to a vast collection of alternative transcripts that integrate transcription…”
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Co-evolution of the branch site and SR proteins in eukaryotes
Published in Trends in genetics (01-12-2008)“…Serine–arginine-rich (SR) proteins are essential for splicing in metazoans but are absent in yeast. By contrast, many fungi have SR protein homologs with…”
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ESTGenes: alternative splicing from ESTs in Ensembl
Published in Genome research (01-05-2004)“…We describe a novel algorithm for deriving the minimal set of nonredundant transcripts compatible with the splicing structure of a set of ESTs mapped on a…”
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