Search Results - "Eynon, N."

Exercise training and DNA methylation in humans by Voisin, S., Eynon, N., Yan, X., Bishop, D. J.

“…The response to exercise training (trainability) has been shown to have a strong heritable component. There is growing evidence suggesting that traits such as…”
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DNA methylation across the genome in aged human skeletal muscle tissue and muscle-derived cells: the role of HOX genes and physical activity by Turner, D. C., Gorski, P. P., Maasar, M. F., Seaborne, R. A., Baumert, P., Brown, A. D., Kitchen, M. O., Erskine, R. M., Dos-Remedios, I., Voisin, S., Eynon, N., Sultanov, R. I., Borisov, O. V., Larin, A. K., Semenova, E. A., Popov, D. V., Generozov, E. V., Stewart, C. E., Drust, B., Owens, D. J., Ahmetov, I. I., Sharples, A. P.

“…Skeletal muscle tissue demonstrates global hypermethylation with age. However, methylome changes across the time-course of differentiation in aged human muscle…”
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Osteocalcin and its forms respond similarly to exercise in males and females by Hiam, D., Landen, S., Jacques, M., Voisin, S., Alvarez-Romero, J., Byrnes, E., Chubb, P., Levinger, I., Eynon, N.

“…Acute exercise increases osteocalcin (OC), a marker of bone turnover, and in particular the undercarboxylated form (ucOC). Males and females differ in baseline…”
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Genetics Variants associated with Anterior Cruciate Ligament injury in Australia, South Africa, and Japan by Alvarez, J., Eynon, N., Hiam, D., Jaques, M., Seale, K., Voisin, S.

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ACTN3 R577X polymorphism and Israeli top-level athletes by Eynon, N, Duarte, J A, Oliveira, J, Sagiv, M, Yamin, C, Meckel, Y, Goldhammer, E

“…A common genetic variation in the alpha-actinin-3 ( ACTN3) gene causes a replacement of an arginine (R) with a premature stop codon (X) at amino-acid 577…”
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Genetic and environmental factors influencing muscle and bone health by Kouw, I., Levinger, I., Eynon, N., Parr, E., Iuliano, S.

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A “human knockout” model to investigate the influence of the α-actinin-3 protein on exercise-induced mitochondrial adaptations by Papadimitriou, I. D., Eynon, N., Yan, X., Munson, F., Jacques, M., Kuang, J., Voisin, S., North, K. N., Bishop, D. J.

“…Research in α-actinin-3 knockout mice suggests a novel role for α-actinin-3 as a mediator of cell signalling. We took advantage of naturally-occurring human…”
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Investigating the influence of mtDNA and nuclear encoded mitochondrial variants on high intensity interval training outcomes by Harvey, N. R., Voisin, S., Lea, R. A., Yan, X., Benton, M. C., Papadimitriou, I. D., Jacques, M., Haupt, L. M., Ashton, K. J., Eynon, N., Griffiths, L. R.

“…Mitochondria supply intracellular energy requirements during exercise. Specific mitochondrial haplogroups and mitochondrial genetic variants have been…”
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Genetic variants associated with exercise performance in both moderately trained and highly trained individuals by Harvey, N. R., Voisin, S., Dunn, P. J., Sutherland, H., Yan, X., Jacques, M., Papadimitriou, I. D., Haseler, L. J., Ashton, K. J., Haupt, L. M., Eynon, N., Griffiths, L. R.

“…Adaptation to exercise training is a complex trait that may be influenced by genetic variants. We identified 36 single nucleotide polymorphisms (SNPs) that had…”
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Genomic haplotype within the Peroxisome Proliferator-Activated Receptor Delta (PPARD) gene is associated with elite athletic status by Maciejewska-Karlowska, A., Hanson, E. D., Sawczuk, M., Cieszczyk, P., Eynon, N.

“…Peroxisome proliferator‐activated receptor delta (PPARδ; encoded by the PPARD gene) plays a role in energy metabolism and mitochondrial function. We have…”
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Is there an interaction between BDKRB2−9/+9 and GNB3 C825T polymorphisms and elite athletic performance? by Eynon, N., Meckel, Y., Alves, A. J., Nemet, D., Eliakim, A.

“…The −9 deletion allele in the BDKRB2 −9/+9 polymorphism was associated previously with improved endurance performance. We compared the frequency distribution…”
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PGC-related gene variants and elite endurance athletic status in a Chinese cohort: A functional study by He, Z-H., Hu, Y., Li, Y-C., Gong, L-J., Cieszczyk, P., Maciejewska-Karlowska, A., Leonska-Duniec, A., Muniesa, C. A., Marín-Peiro, M., Santiago, C., Garatachea, N., Eynon, N., Lucia, A.

“…This study aims to examine the association between proliferator‐activated receptor γ (PGC)‐gene family‐related single nucleotide polymorphisms (SNPs) and elite…”
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The C allele in NOS3 -786 T/C polymorphism is associated with elite soccer player's status by Eynon, N, Ruiz, J R, Yvert, T, Santiago, C, Gómez-Gallego, F, Lucia, A, Birk, R

“…The NOS3-786 T/C polymorphism (rs2070744) is a candidate to explain individual variations in sports related phenotypes. We determined the genotype and allele…”
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Is there an ACE ID - ACTN3 R577X polymorphisms interaction that influences sprint performance? by Eynon, N, Alves, A J, Yamin, C, Sagiv, M, Duarte, J A, Oliveira, J, Ayalon, M, Goldhammer, E, Meckel, Y

“…Functional R577X (rs.1815739) and ID (rs.5186) polymorphisms in the alpha-actinin-3 ( ACTN3) and the angiotensin converting enzyme (ACE) genes, respectively,…”
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GNB3 C825T Polymorphism and elite athletic status: A replication study with two ethnic groups by Ruiz, J R, Eynon, N, Meckel, Y, Fiuza-Luces, C, Santiago, C, Gómez-Gallego, F, Oliveira, J, Lucia, A

“…We aimed to replicate the original findings by Eynon et al. showing an association between the T allele of the GNB3 C825T polymorphism and elite endurance…”
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Supraglottitis and abscess formation by Gillett, D, Eynon-Lewis, N J

“…This case series report aims to raise awareness of the association between supraglottic infection and abscess formation, which has been rarely documented. We…”
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THE GSTP1 c.313A>G POLYMORPHISM MODULATES THE CARDIORESPIRATORY RESPONSE TO AEROBIC TRAINING by Zarebska, A, Jastrzebski, Z, Kaczmarczyk, M, Ficek, K, Maciejewska-Karlowska, A, Sawczuk, M, Leońska-Duniec, A, Krol, P, Cieszczyk, P, Zmijewski, P, Eynon, N

“…The GSTP1 c.313A>G polymorphism is a candidate to explain some of the individual differences in cardiorespiratory fitness phenotypes' responses to aerobic…”
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GNAS A-1121G variant is associated with improved diastolic dysfunction in response to exercise training in heart failure patients by Alves, A J, Goldhammer, E, Ribeiro, F, Eynon, N, Ben-Zaken Cohen, S, Duarte, J A, Viana, J L, Sagiv, M, Oliveira, J

“…β1-adrenergic receptors (ADRB1) and Gαs proteins (GNAS) play important roles in the regulation of cardiac function. The present study sought to investigate…”
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Is otalgia a suitable symptom to be managed by Pharmacy First? by Lakhani, R., Eynon-Lewis, N.

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CK-MM gene polymorphism does not influence the blood CK activity levels after exhaustive eccentric exercise by Yamin, C, Oliveira, J, Meckel, Y, Eynon, N, Sagiv, M, Ayalon, M, Alves, A J, Duarte, J A

“…Gene variants, such as creatine kinase (CK) polymorphisms, have been suggested to explain the inter-individual blood CK response to eccentric exercise…”
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