Search Results - "Expert opinion on biological therapy"

Platelet-rich plasma for the treatment of knee osteoarthritis: an expert opinion and proposal for a novel classification and coding system by Kon, Elizaveta, Di Matteo, Berardo, Delgado, Diego, Cole, Brian J, Dorotei, Andrea, Dragoo, Jason L, Filardo, Giuseppe, Fortier, Lisa A, Giuffrida, Alberto, Jo, Chris H, Magalon, Jeremy, Malanga, Gerard A, Mishra, Allan, Nakamura, Norimasa, Rodeo, Scott A, Sampson, Steven, Sánchez, Mikel

“…Platelet-rich plasma (PRP) is able to modulate the joint environment by reducing the inflammatory distress and promoting tissue anabolism. Therefore, it has…”
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TRUCKs: the fourth generation of CARs by Chmielewski, Markus, Abken, Hinrich

“…Adoptive cell therapy of malignant diseases takes advantage of the cellular immune system to recognize and destroy cancer cells. This is impressively…”
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Emerging trends and new developments in regenerative medicine: a scientometric update (2000 - 2014) by Chen, Chaomei, Dubin, Rachael, Kim, Meen Chul

“…Our previous scientometric review of regenerative medicine provides a snapshot of the fast-growing field up to the end of 2011. The new review identifies…”
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An overview of antimicrobial peptides and the latest advances in their development by Sierra, Josep M, Fusté, Ester, Rabanal, Francesc, Vinuesa, Teresa, Viñas, Miguel

“…The recent dramatic increase in the incidence of antimicrobial resistance has been recognized by organizations such as the United Nations and World Health…”
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Diabetic retinopathy: a complex pathophysiology requiring novel therapeutic strategies by Whitehead, Michael, Wickremasinghe, Sanjeewa, Osborne, Andrew, Van Wijngaarden, Peter, Martin, Keith R

“…Diabetic retinopathy (DR) is the leading cause of vision loss in the working age population of the developed world. DR encompasses a complex pathology, and one…”
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Emerging trends in regenerative medicine: a scientometric analysis in CiteSpace by Chen, Chaomei, Hu, Zhigang, Liu, Shengbo, Tseng, Hung

“…Regenerative medicine involves research in a number of fields and disciplines such as stem cell research, tissue engineering and biological therapy in general…”
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Inflammatory cytokines: from discoveries to therapies in IBD by Marafini, Irene, Sedda, Silvia, Dinallo, Vincenzo, Monteleone, Giovanni

“…: Although the etiology of inflammatory bowel diseases (IBD) remains unknown, accumulating evidence suggests that the intestinal tissue damage in these…”
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Stem cell therapies for wound healing by Kosaric, Nina, Kiwanuka, Harriet, Gurtner, Geoffrey C

“…Aberrant wound healing is a significant healthcare problem, posing a substantial burden on patients, their families, and the healthcare system. Existing…”
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An update on therapies for the treatment of diabetes-induced osteoporosis by Mohsin, Sahar, Baniyas, May Myh, AlDarmaki, Reem Smh, Tekes, Kornélia, Kalász, Huba, Adeghate, Ernest A

“…: Currently, 424 million people aged between 20 and 79 years worldwide are diabetic. More than 25% of adults aged over 65 years in North America have Type 2…”
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Modern use of 5-aminosalicylic acid compounds for ulcerative colitis by Le Berre, Catherine, Roda, Giulia, Nedeljkovic Protic, Marijana, Danese, Silvio, Peyrin-Biroulet, Laurent

“…: For 30 years, 5-aminosalicylic acid (5-ASA) has been the backbone of therapeutic management in patients with ulcerative colitis (UC). In the biologic era, it…”
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Current challenges in biotherapeutic particles manufacturing by Moleirinho, Mafalda G, Silva, Ricardo J S, Alves, Paula M, Carrondo, Manuel J T, Peixoto, Cristina

“…: The development of novel complex biotherapeutics led to new challenges in biopharmaceutical industry. The potential of these particles has been demonstrated…”
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Recent advances in gelatin-based therapeutics by Echave, Mari Carmen, Hernáez-Moya, Raquel, Iturriaga, Leire, Pedraz, José Luis, Lakshminarayanan, Rajamani, Dolatshahi-Pirouz, Alireza, Taebnia, Nayere, Orive, Gorka

“…Biomaterials have provided a wide range of exciting opportunities in tissue engineering and regenerative medicine. Gelatin, a collagen-derived natural…”
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Advances in the formation, use and understanding of multi-cellular spheroids by Achilli, Toni-Marie, Meyer, Julia, Morgan, Jeffrey R

“…Developing in vitro models for studying cell biology and cell physiology is of great importance to the fields of biotechnology, cancer research, drug…”
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New frontiers in personalized medicine in psoriasis by Camela, Elisa, Potestio, Luca, Fabbrocini, Gabriella, Ruggiero, Angelo, Megna, Matteo

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Sacituzumab govitecan, a novel, third-generation, antibody-drug conjugate (ADC) for cancer therapy by Goldenberg, David M, Sharkey, Robert M

“…We describe a new, third-generation of antibody-drug conjugates (ADCs) having a high drug payload against topoisomerase I, important for DNA function, and…”
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Mesenchymal stem cell derived secretome and extracellular vesicles for acute lung injury and other inflammatory lung diseases by Monsel, Antoine, Zhu, Ying-Gang, Gudapati, Varun, Lim, Hyungsun, Lee, Jae W

“…Acute respiratory distress syndrome is a major cause of respiratory failure in critically ill patients. Despite extensive research into its pathophysiology,…”
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Therapeutic potential of mesenchymal stem/stromal cell-derived secretome and vesicles for lung injury and disease by Liu, Airan, Zhang, Xiwen, He, Hongli, Zhou, Li, Naito, Yoshifumi, Sugita, Shinji, Lee, Jae-Woo

“…: The acute respiratory distress syndrome (ARDS) is a devastating clinical condition common in patients with respiratory failure. Based largely on numerous…”
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Treating psoriasis in the elderly: biologics and small molecules by Megna, Matteo, Potestio, Luca, Fabbrocini, Gabriella, Camela, Elisa

“…Psoriasis prevalence in the elderly is growing. It is estimated that 15% of elderly psoriasis patients suffer from moderate-to-severe disease, thus requiring…”
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Half-life extended biotherapeutics by Kontermann, Roland E

“…Many of the biotherapeutics approved or under development suffer from a short half-life necessitating frequent applications in order to maintain a therapeutic…”
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Antibody-drug conjugates (ADCs) delivering pyrrolobenzodiazepine (PBD) dimers for cancer therapy by Hartley, John A

“…The rationally designed pyrrolobenzodiazepine (PBD) dimers emerged around ten years ago as a new class of drug component for antibody-drug conjugates (ADC)…”
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